Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Barak W. Gunter"'
Autor:
Laura B. Teal, Robert W. Gould, Michael Bubser, Robert T. Matthews, Danny G. Winder, Aaron T. Garrison, Madeline G. Ragland, Thomas M. Bridges, Craig W. Lindsley, Carrie K. Jones, Barak W. Gunter
Publikováno v:
ACS Chemical Neuroscience. 10:3740-3750
Opioid use disorder (OUD) is a debilitating neuropsychiatric condition characterized by compulsive opioid use, dependence, and repeated relapse after periods of abstinence. Given the high risk of d...
Autor:
Carlos Zgheib, Mazen Kurdi, Fouad A Zouein, Barak W Gunter, Brian A Stanley, Joe Zgheib, Damian G Romero, S Bruce King, Nazareno Paolocci, George W Booz
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43313 (2012)
We previously showed that oxidative stress inhibits leukemia inhibitory factor (LIF) signaling by targeting JAK1, and the catalytic domains of JAK 1 and 2 have a cysteine-based redox switch. Thus, we postulated that the NO sibling and thiophylic comp
Externí odkaz:
https://doaj.org/article/689f91502ad44631a8a6a0d03f648800
Autor:
Nicholas J. Brandon, Mark E. Duggan, Colleen M. Niswender, Jacob Ball, Barak W. Gunter, Michael Bubser, Carrie K. Jones, Michael D. Grannan, P. Jeffrey Conn, Thomas M. Bridges, Craig W. Lindsley, Michael W. Wood, Robert W. Gould, Jürgen Wess
Publikováno v:
Neuropharmacology. 128:492-502
Although selective activation of the M1 muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of neuropsychiatric disorders, recent evidence suggests that enhancing M4 mAChR function can also
Autor:
Kevin M. McGowan, Craig W. Lindsley, Barak W. Gunter, Michael Bubser, Carrie K. Jones, Robert W. Gould
Publikováno v:
Addiction Biology. 23:1106-1116
Cocaine use disorder (CUD) remains a debilitating health problem in the United States for which there are no Food and Drug Administration-approved treatment options. Accumulating anatomical and electrophysiological evidence indicates that the muscari
Autor:
Robert W, Gould, Barak W, Gunter, Michael, Bubser, Robert T, Matthews, Laura B, Teal, Madeline G, Ragland, Thomas M, Bridges, Aaron T, Garrison, Danny G, Winder, Craig W, Lindsley, Carrie K, Jones
Publikováno v:
ACS Chem Neurosci
Opioid Use Disorder (OUD) is a debilitating neuropsychiatric condition characterized by compulsive opioid use, dependence, and repeated relapse after periods of abstinence. Given the high risk of developing OUD following prescription opioid use, the
Autor:
Ian A. Paul, Craig A. Stockmeier, Martin O. Bohlen, Barak W. Gunter, Quentin Henry, Muhammad S. Riaz
Publikováno v:
Physiology & Behavior. 152:128-134
Exposure to unpredictable chronic mild stress (CUS) is a commonly used protocol in rats that is reported to evoke antidepressant-reversible behaviors such as loss of preference for a sweetened water solution which is taken as an analog of the anhedon
Publikováno v:
Pharmacology Biochemistry and Behavior. 137:53-59
Benzodiazepines are positive allosteric modulators of the GABAA receptor and are prescribed as anxiolytics, hypnotics, and anticonvulsants. While these drugs clearly have clinical value, their use is associated with unwanted side effects such as seda
Cognitive enhancement and antipsychotic-like activity following repeated dosing with the selective M
Autor:
Robert W, Gould, Michael D, Grannan, Barak W, Gunter, Jacob, Ball, Michael, Bubser, Thomas M, Bridges, Jurgen, Wess, Michael W, Wood, Nicholas J, Brandon, Mark E, Duggan, Colleen M, Niswender, Craig W, Lindsley, P Jeffrey, Conn, Carrie K, Jones
Publikováno v:
Neuropharmacology. 128
Although selective activation of the M(1) muscarinic acetylcholine receptor (mAChR) subtype has been shown to improve cognitive function in animal models of neuropsychiatric disorders, recent evidence suggests that enhancing M(4) mAChR function can a
Autor:
Barak W, Gunter, Robert W, Gould, Michael, Bubser, Kevin M, McGowan, Craig W, Lindsley, Carrie K, Jones
Publikováno v:
Addiction biology. 23(5)
Cocaine use disorder (CUD) remains a debilitating health problem in the United States for which there are no FDA-approved treatment options. Accumulating anatomical and electrophysiological evidence indicates that the muscarinic acetylcholine recepto
Publikováno v:
Psychopharmacology. 233(17)
Benzodiazepines are effective anxiolytics, hypnotics, and anticonvulsants but unwanted side effects, including abuse potential, limit their use. A possible strategy to increase the therapeutic index of this drug class is to combine benzodiazepines wi