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CF102 for the Treatment of Hepatocellular Carcinoma: A Phase I/II, Open-Label, Dose-Escalation Study
Autor:
Pnina Fishman, Ofer Benjaminov, William D Kerns, Barak Singer, Salomon M. Stemmer, Motti Farbstein, Renana Petoka, Sara Bar Yehuda, Noa Beatrice Ciuraru, Gal Medalia, Sari Fishman, Shira Cohen, Zivit Harpaz, Michael H Silverman
Publikováno v:
The Oncologist. 18:25-26
Background. The A3 adenosine receptor (A3AR) is overexpressed in the tumor and in the peripheral blood mononuclear cells of patients with hepatocellular carcinoma (HCC). The orally active drug candidate CF102, an A3AR agonist, induces apoptosis of HC