Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Barak Reicher"'
Autor:
Chen Ankri, Oren Hershkovitz, Liat Hershkovitz, Meital Brami, Ronnie Levy, Hadar Sarig, Einat Souli, Barak Reicher, Veronique Amor-Baroukh, Dror Mevorach, Abraham Nyska
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 426 (2024)
Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed
Externí odkaz:
https://doaj.org/article/484daee91bb9477a925e671ae104f69b
Autor:
Peter Vernon van Heerden, Avraham Abutbul, Ahmad Naama, Shlomo Maayan, Nassar Makram, Akiva Nachshon, Kamal abu Jabal, Oren Hershkovitz, Lior Binder, Yehudit Shabat, Barak Reicher, Dror Mevorach
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundHyper-inflammatory immune response, a hallmark of severe COVID-19, is associated with increased mortality. Acute respiratory distress syndrome (ARDS) is a common manifestation. We undertook two phase I/II studies in five and then 16 subject
Externí odkaz:
https://doaj.org/article/e29d0b2a646945f09b490ac645c1c130
Autor:
Peter Vernon van Heerden, Avraham Abutbul, Sigal Sviri, Eitan Zlotnick, Ahmad Nama, Sebastian Zimro, Raja el-Amore, Yehudit Shabat, Barak Reicher, Batla Falah, Dror Mevorach
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundSepsis has no proven specific pharmacologic treatment and reported mortality ranges from 30%–45%. The primary aim of this phase IB study was to determine the safety profile of Allocetra™-OTS (early apoptotic cell) infusion in subjects p
Externí odkaz:
https://doaj.org/article/30396d5741914c408c571672bf123aa2
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce995546510b19c2f47e39ce2a9ea39
https://doi.org/10.1136/jitc-2022-sitc2022.1380
https://doi.org/10.1136/jitc-2022-sitc2022.1380
Autor:
Ronen Beeri, Ran Eliaz, Barak Reicher, Dror Mevorach, Netanel Karbian, Raja el-Amore, Avraham Abutbul
Publikováno v:
Cell Death and Disease, Vol 11, Iss 7, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Sepsis has no proven pharmacologic treatment other than appropriate antibiotic agents, fluids, vasopressors as needed, and possibly corticosteroids. It is generally initiated mainly by the simultaneous recognition by various components of the innate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3048860fa8a84c1cfa0aa99ac6b4c2
http://link.springer.com/article/10.1038/s41419-020-02748-8
http://link.springer.com/article/10.1038/s41419-020-02748-8
Publikováno v:
Journal of Clinical Oncology. 40:2532-2532
2532 Background: Chimeric antigen receptor (CAR) T cells can activate an immune response to a cancer-specific antigen but is less effective in solid tumors. Immune check point inhibitors (ICI) revolutionized the treatment of solid tumors, however, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02ec30df1578985201f90ed01b7b0955
https://doi.org/10.1200/jco.2022.40.16_suppl.2532
https://doi.org/10.1200/jco.2022.40.16_suppl.2532
Autor:
Batla Falah, Yehudit Shabat, Raja el-Amore, Sigal Sviri, Barak Reicher, Avraham Abutbul, Ahmad Nama, Sebastian Zimro, Peter Vernon van Heerden, Dror Mevorach, Eithan Zlotnik
SummaryBackgroundSepsis has no proven specific pharmacologic treatment. Reported mortality in sepsis ranges from 30%–45%. This study was designed to determine the safety preliminary efficacy of allogenic apoptotic cells administered for immunomodul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54f4c865825f8d81ef648d710545839a
https://doi.org/10.1101/2020.12.03.20242586
https://doi.org/10.1101/2020.12.03.20242586
Autor:
Noah Joseph, Shlomi Jakubowicz, Orly Perl, Mira Barda-Saad, Maor H. Pauker, Inbal Wortzel, Barak Reicher, Elad Noy
Publikováno v:
Journal of Biological Chemistry. 289:34503-34519
T cell antigen receptor (TCR) engagement has been shown to activate pathways leading to actin cytoskeletal polymerization and reorganization, which are essential for lymphocyte activation and function. Several actin regulatory proteins were implicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a420f2e881f19a6da6eda436bb6573
https://doi.org/10.1074/jbc.m114.591685
https://doi.org/10.1074/jbc.m114.591685
Autor:
Barak Reicher, Sophia Fried, Elad Noy, Guy Biber, Batel Sabag, Noah Joseph, Mira Barda-Saad, Omer Levy
Publikováno v:
Scientific Reports
WASp family Verprolin-homologous protein-2 (WAVE2), a member of the Wiskott-Aldrich syndrome protein (WASp) family of actin nucleation promoting factors, is a central regulator of actin cytoskeleton polymerization and dynamics. Multiple signaling pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ed1b7836784ee29c289769489c363b
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1838(2):557-568
During T cell activation, the engagement of a T cell with an antigen-presenting cell (APC) results in rapid cytoskeletal rearrangements and a dramatic increase of intracellular calcium (Ca(2+)) concentration, downstream to T cell antigen receptor (TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d269360b46472b3a0ee4fbbda9a220f6