Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Barak Raveh"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
T cells respond swiftly, specifically, sensitively, and robustly to cognate antigens presented on the surface of antigen presenting cells. Existing microscopic models capture various aspects of early T-cell antigen receptor (TCR) signaling at the mol
Externí odkaz:
https://doaj.org/article/4e1d1ac003e945119cd4ea87e79a26aa
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18934 (2011)
Flexible peptides that fold upon binding to another protein molecule mediate a large number of regulatory interactions in the living cell and may provide highly specific recognition modules. We present Rosetta FlexPepDock ab-initio, a protocol for si
Externí odkaz:
https://doaj.org/article/ba64ffc8d22344e9bef42e750d34b527
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 2, p e1000295 (2009)
Proteins are active, flexible machines that perform a range of different functions. Innovative experimental approaches may now provide limited partial information about conformational changes along motion pathways of proteins. There is therefore a ne
Externí odkaz:
https://doaj.org/article/32573e12464a40a8a863bffe9bd70563
Autor:
Toshiya Kozai, Javier Fernandez-Martinez, Trevor van Eeuwen, Paola Gallardo, Larisa E. Kapinos, Adam Mazur, Wenzhu Zhang, Jeremy Tempkin, Radhakrishnan Panatala, Maria Delgado-Izquierdo, Barak Raveh, Andrej Sali, Brian T. Chait, Liesbeth M. Veenhoff, Michael P. Rout, Roderick Y. H. Lim
Nuclear pore complexes (NPCs) mediate nucleocytoplasmic transport of specific macromolecules while impeding the exchange of unsolicited material. However, key aspects of this gating mechanism remain controversial. To address this issue, we determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c479bc774ff96fe6fb7c8fe212cc3b23
https://doi.org/10.1101/2023.03.31.535055
https://doi.org/10.1101/2023.03.31.535055
Autor:
Ion Andreu, Ignasi Granero-Moya, Nimesh R. Chahare, Kessem Clein, Marc Molina-Jordán, Amy E. M. Beedle, Alberto Elosegui-Artola, Juan F. Abenza, Leone Rossetti, Xavier Trepat, Barak Raveh, Pere Roca-Cusachs
Publikováno v:
Nature Cell Biology
Mechanical force controls fundamental cellular processes in health and disease, and increasing evidence shows that the nucleus both experiences and senses applied forces. Such forces can lead to the nuclear translocation of proteins, but whether forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc150cdc63f4bc3d723eacdf662fd89f
https://hdl.handle.net/2117/383728
https://hdl.handle.net/2117/383728
The pancreatic islet (islet of Langerhans) is a mini-organ comprising several thousand endocrine cells, functioning jointly to maintain normoglycemia. Cellular networks within an islet were shown to influence its function in health and disease, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec36a3211c27ae6ee995916fe7a2d54
https://doi.org/10.1101/2021.11.07.467656
https://doi.org/10.1101/2021.11.07.467656
Autor:
Liping Sun, Carl Kesselman, Jitin Singla, Kala Bharath, Dongqing Zheng, Raymond C. Stevens, Kate L. White, Angdi Li, Andrej Sali, Jeremy O. B. Tempkin, Nicholas A. Graham, Barak Raveh, Tanmoy Sanyal, Chenxi Wang, Jihui Zhao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 35
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Comprehensive modeling of a whole cell requires an integration of vast amounts of information on various aspects of the cell and its parts. To divide and conquer this task, we introduce Bayesian metamodeling, a general approach to modeling complex sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4745692c5dba536cbf01a37c1bf3e3e0
https://doi.org/10.1073/pnas.2104559118
https://doi.org/10.1073/pnas.2104559118
Autor:
Alberto Elosegui-Artola, Amy E. M. Beedle, Xavier Trepat, Ion Andreu, Ignasi Granero, Pere Roca-Cusachs, Barak Raveh, Nimesh Chahare, Kessem Clein, Marc Molina Jordan
Mechanical force controls fundamental cellular processes in health and disease, and increasing evidence shows that the nucleus both experiences and senses applied forces. Here we show that nuclear forces differentially control passive and facilitated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b998ee28702876e73bf3cf540bdc9a81
https://doi.org/10.1101/2021.07.23.453478
https://doi.org/10.1101/2021.07.23.453478
Autor:
Riccardo Pellarin, Ilona Nudelman, Zhiheng Yu, Brian T. Chait, Joanna A. Hogan, Brian D. Slaughter, Javier Fernandez-Martinez, Seung Joong Kim, Jennifer L. Gerton, Charles H. Greenberg, Rosemary Williams, Paula Upla, Barak Raveh, Steven J. Ludtke, Ignacia Echeverria, David L. Stokes, Andrej Sali, Azraa S. Chaudhury, John D. Aitchison, Wenzhu Zhang, Manjunatha Shivaraju, Jay R. Unruh, Thurston Herricks, Christopher W. Akey, Erica Y. Jacobs, Ilan E. Chemmama, Yi Shi, Martin F. Jarrold, Roxana Mironska, Michael P. Rout, M. Jason de la Cruz, Junjie Wang
Publikováno v:
Nature
Nature, Nature Publishing Group, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, Nature Publishing Group, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nature, 2018, 555 (7697), pp.475-482. ⟨10.1038/nature26003⟩
Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have impeded a full structural and functional elucidation. Here we determined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf1df4e9114f902daba1f64b28db9fe
https://doi.org/10.1038/nature26003
https://doi.org/10.1038/nature26003
Autor:
Jack Maguire, Ragul Gowthaman, Marion F. Sauer, Georg Kuenze, Tanja Kortemme, Benjamin Basanta, Indigo Chris King, Jens Meiler, Rhiju Das, Ora Schueler-Furman, Nicholas A. Marze, Brandon Frenz, Christoffer Norn, Julia Koehler Leman, Jason W. Labonte, Kala Bharath Pilla, Lei Shi, Sergey Lyskov, Brian D. Weitzner, Nir London, Karen R. Khar, Jaume Bonet, Nawsad Alam, Andreas Scheck, Alexander M. Sevy, Lars Malmström, Thomas Huber, Christopher Bystroff, Lior Zimmerman, Lorna Dsilva, Bruno E. Correia, Roland L. Dunbrack, Sergey Ovchinnikov, Rocco Moretti, Scott Horowitz, Phil Bradley, Frank DiMaio, Noah Ollikainen, Brian Kuhlman, Jeffrey J. Gray, Melanie L. Aprahamian, Andrew Leaver-Fay, Santrupti Nerli, Brian Koepnick, Xingjie Pan, Manasi A. Pethe, Andrew M. Watkins, Summer B. Thyme, Enrique Marcos, Vikram Khipple Mulligan, Hahnbeom Park, Po-Ssu Huang, David K. Johnson, Daniel-Adriano Silva, Patrick Barth, Shannon Smith, Caleb Geniesse, Jason K. Lai, Patrick Conway, Amelie Stein, Jeliazko R. Jeliazkov, David Baker, Dominik Gront, Kalli Kappel, Firas Khatib, Robert Kleffner, Brian J. Bender, Richard Bonneau, Kyle A. Barlow, Joseph H. Lubin, Shourya S. Roy Burman, Nikolaos G. Sgourakis, Yuval Sedan, Ryan E. Pavlovicz, Kristin Blacklock, Seth Cooper, Barak Raveh, Alisa Khramushin, John Karanicolas, Justin B. Siegel, Sharon L. Guffy, Brian G. Pierce, Alex Ford, Darwin Y. Fu, Orly Marcu, Gideon Lapidoth, Brian Coventry, René M. de Jong, Shane O’Conchúir, Thomas W. Linsky, William R. Schief, Rebecca F. Alford, Scott E. Boyken, Sagar D. Khare, Maria Szegedy, Ray Yu-Ruei Wang, Steven M. Lewis, Hamed Khakzad, Timothy M. Jacobs, Frank D. Teets, Lukasz Goldschmidt, Daisuke Kuroda, Steffen Lindert, P. Douglas Renfrew, Yifan Song, Jared Adolf-Bryfogle, Michael S. Pacella, Aliza B. Rubenstein
Publikováno v:
Nat Methods
The Rosetta software for macromolecular modeling, docking and design is extensively used in laboratories worldwide. During two decades of development by a community of laboratories at more than 60 institutions, Rosetta has been continuously refactore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c561276e840d68005d2aab06fb9642da
https://pubmed.ncbi.nlm.nih.gov/32483333
https://pubmed.ncbi.nlm.nih.gov/32483333