Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Baptiste Panthu"'
Autor:
Zoé Daverio, Maxime Kolkman, Johan Perrier, Lexane Brunet, Nadia Bendridi, Corinne Sanglar, Marie-Agnès Berger, Baptiste Panthu, Gilles J. P. Rautureau
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Lactate accumulation and acidification in tumours are a cancer hallmark associated with the Warburg effect. Lactic acidosis correlates with cancer malignancy, and the benefit it offers to tumours has been the subject of numerous hypotheses.
Externí odkaz:
https://doaj.org/article/8cd5baad18be4c728dc663eda9f56d24
Autor:
Eva Drevet Mulard, Sylvie Guibert, Anne Mey, Camille Lefevre, Marie-Agnès Chauvin, Claudie Pinteur, Marie-Ambre Monet, Murielle Godet, Anne-Marie Madec, Béatrice Morio, Jennifer Rieusset, Gilles J. P. Rautureau, Baptiste Panthu
Publikováno v:
Nutrients, Vol 16, Iss 6, p 803 (2024)
Obesity is a risk factor for many diseases, such as type 2 diabetes and cardiovascular diseases. In line with the need for precision medicine, the search for biomarkers reporting the progression of obesity- and diet-associated disorders is urgent. We
Externí odkaz:
https://doaj.org/article/2e03d4a1762245e48582051a3ea6aa91
Autor:
Matthieu Leuillier, Thomas Duflot, Séverine Ménoret, Hind Messaoudi, Zoubir Djerada, Déborah Groussard, Raphaël G.P. Denis, Laurence Chevalier, Ahmed Karoui, Baptiste Panthu, Pierre-Alain Thiébaut, Isabelle Schmitz-Afonso, Séverine Nobis, Cynthia Campart, Tiphaine Henry, Camille Sautreuil, Serge H. Luquet, Olivia Beseme, Catherine Féliu, Hélène Peyret, Lionel Nicol, Jean-Paul Henry, Sylvanie Renet, Paul Mulder, Debin Wan, Laurent Tesson, Jean-Marie Heslan, Angéline Duché, Sébastien Jacques, Frédéric Ziegler, Valéry Brunel, Gilles J.P. Rautureau, Christelle Monteil, Jean-Luc do Rego, Jean-Claude do Rego, Carlos Afonso, Bruce Hammock, Anne-Marie Madec, Florence Pinet, Vincent Richard, Ignacio Anegon, Christophe Guignabert, Christophe Morisseau, Jérémy Bellien
Publikováno v:
Journal of Advanced Research, Vol 43, Iss , Pp 163-174 (2023)
Introduction: Although the physiological role of the C-terminal hydrolase domain of the soluble epoxide hydrolase (sEH-H) is well investigated, the function of its N-terminal phosphatase activity (sEH-P) remains unknown. Objectives: This study aimed
Externí odkaz:
https://doaj.org/article/ae3d2c7efa674a65a28617072bd9a0df
Autor:
Johan Perrier, Margaux Nawrot, Anne-Marie Madec, Karim Chikh, Marie-Agnès Chauvin, Christian Damblon, Julia Sabatier, Charles H. Thivolet, Jennifer Rieusset, Gilles J. P. Rautureau, Baptiste Panthu
Publikováno v:
Nutrients, Vol 15, Iss 22, p 4791 (2023)
Progressive decline in pancreatic beta-cell function is central to the pathogenesis of type 2 diabetes (T2D). Here, we explore the relationship between the beta cell and its nutritional environment, asking how an excess of energy substrate leads to a
Externí odkaz:
https://doaj.org/article/341a53787e7045499d77bf2dda2c0387
Autor:
Nannan Wu, Xuan-Nhi Nguyen, Li Wang, Romain Appourchaux, Chengfei Zhang, Baptiste Panthu, Henri Gruffat, Chloé Journo, Sandrine Alais, Juliang Qin, Na Zhang, Kevin Tartour, Frédéric Catez, Renaud Mahieux, Theophile Ohlmann, Mingyao Liu, Bing Du, Andrea Cimarelli
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011176 (2023)
[This corrects the article DOI: 10.1371/journal.ppat.1008093.].
Externí odkaz:
https://doaj.org/article/eda1ced904054856aebe7c69698f4dc6
Autor:
Gabriel Therizols, Zeina Bash-Imam, Baptiste Panthu, Christelle Machon, Anne Vincent, Julie Ripoll, Sophie Nait-Slimane, Mounira Chalabi-Dchar, Angéline Gaucherot, Maxime Garcia, Florian Laforêts, Virginie Marcel, Jihane Boubaker-Vitre, Marie-Ambre Monet, Céline Bouclier, Christophe Vanbelle, Guillaume Souahlia, Elise Berthel, Marie Alexandra Albaret, Hichem C. Mertani, Michel Prudhomme, Martin Bertrand, Alexandre David, Jean-Christophe Saurin, Philippe Bouvet, Eric Rivals, Théophile Ohlmann, Jérôme Guitton, Nicole Dalla Venezia, Julie Pannequin, Frédéric Catez, Jean-Jacques Diaz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Different mechanisms have been reported to explain resistance to chemotherapy in cancer. Here, the authors show that the chemotherapeutic drug 5-fluorouracil alters the function of ribosomes to promote pro-survival gene translation leading to chemoth
Externí odkaz:
https://doaj.org/article/8864c0c71ca844a0835d6a8c1a22dd59
Autor:
G. J. P. Rautureau, B. Morio, S. Guibert, C. Lefevre, J. Perrier, A. Alves, M. A. Chauvin, C. Pinteur, M. A. Monet, M. Godet, A. M. Madec, J. Rieusset, A. Mey, Baptiste Panthu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Obesity is associated with both chronic and acute respiratory illnesses, such as asthma, chronic obstructive pulmonary disease (COPD) or increased susceptibility to infectious diseases. Anatomical but also systemic and local metabolic altera
Externí odkaz:
https://doaj.org/article/148fabfed23f4120bb75b285e1db733a
Autor:
Laure Perrin-Cocon, Pierre-Olivier Vidalain, Clémence Jacquemin, Anne Aublin-Gex, Keedrian Olmstead, Baptiste Panthu, Gilles Jeans Philippe Rautureau, Patrice André, Piotr Nyczka, Marc-Thorsten Hütt, Nivea Amoedo, Rodrigue Rossignol, Fabian Volker Filipp, Vincent Lotteau, Olivier Diaz
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Many cancers fuel their rapid growth by replacing glucokinase with its higher affinity isoenzyme, hexokinase 2 (HK2), making HK2 an attractive drug target. In this study, Perrin-Cocon and Vidalain et al. use CRISPR/Cas-9 gene editing to reverse this
Externí odkaz:
https://doaj.org/article/a519b0af2fba49868394944910f843d0
Publikováno v:
Cancers, Vol 15, Iss 5, p 1417 (2023)
Lactic acidosis, a hallmark of solid tumour microenvironment, originates from lactate hyperproduction and its co-secretion with protons by cancer cells displaying the Warburg effect. Long considered a side effect of cancer metabolism, lactic acidosis
Externí odkaz:
https://doaj.org/article/f1e8dbfbdc514f2fa8b8027507b4ab4b
Autor:
Anaïs Alves, Frédéric Lamarche, Rémy Lefebvre, Eva Drevet Mulard, Arthur Bassot, Stéphanie Chanon, Emmanuelle Loizon, Claudie Pinteur, Aline Maria Nunes de Lira Gomes Bloise, Murielle Godet, Gilles J. P. Rautureau, Baptiste Panthu, Béatrice Morio
Publikováno v:
Nutrients, Vol 15, Iss 1, p 96 (2022)
Interactions between mitochondria and the endoplasmic reticulum, known as MAMs, are altered in the liver in obesity, which contributes to disruption of the insulin signaling pathway. In addition, the plasma level of glycine is decreased in obesity, a
Externí odkaz:
https://doaj.org/article/1caf037b23b34c5eb14f69c6d72b6137