Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Baptiste Fours"'
Publikováno v:
Organic Process Research & Development. 22:321-327
The results of our process development studies to synthesize the methanol solvate of (S)-omeprazole potassium salt (1) through the enantioselective oxidation of pyrmetazole (2) using (1R)-(−)-10-camphorsulfonyloxaziridine (3) are reported. Optical
Publikováno v:
Faraday Discussions
Faraday Discussions, Royal Society of Chemistry, 2015, 179, pp.475-488. ⟨10.1039/C4FD00222A⟩
Faraday Discussions, Royal Society of Chemistry, 2015, 179, pp.475-488. ⟨10.1039/C4FD00222A⟩
Rimonabant monohydrate can be dehydrated at 100 °C or above with complete loss of structural information; in this case the amorphous material can lead to nucleation and crystal growth. The water molecules can also be removed by a smooth process belo
Autor:
Julien Mahieux, Luc Quere, Luc Aerts, Gérard Coquerel, Eric Schenkel, Nicolas Couvrat, Baptiste Fours, Yohann Cartigny
Publikováno v:
International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2016, 515 (1-2), pp.702-707. ⟨10.1016/j.ijpharm.2016.11.003⟩
International Journal of Pharmaceutics, Elsevier, 2016, 515 (1-2), pp.702-707. ⟨10.1016/j.ijpharm.2016.11.003⟩
Brivaracetam, or (2S)-2-[(4R)-2-oxo-4-propyl-pyrrolidin-1-yl] butanamide, is an active pharmaceutical ingredient designed for the treatment of epilepsy. During the development of the IV administration mode, a liquid-liquid miscibility gap has been ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72acd17ddd05efaa6f8243fbef813aef
https://hal-normandie-univ.archives-ouvertes.fr/hal-01928640
https://hal-normandie-univ.archives-ouvertes.fr/hal-01928640
Autor:
Fabrizia Grepioni, Luc Quere, Gérard Coquerel, Geraldine Longfils, Sandrine Rome, Luc Aerts, Johan Wouters, Dario Braga, Saverio Nanna, Baptiste Fours
Publikováno v:
CrystEngComm
CrystEngComm, Royal Society of Chemistry, 2014, 16 (26), pp.5887-5896. ⟨10.1039/C4CE00409D⟩
CrystEngComm, Royal Society of Chemistry, 2014, 16 (26), pp.5887-5896. ⟨10.1039/C4CE00409D⟩
Mechanochemical and solution based reactions of solid brivaracetam (BRV) and seletracetam (SEL), antiepileptic drugs from UCB's pipeline, with the inorganic salts MgCl2 and CaCl2, yield ionic co-crystals with changed or improved physico-chemical prop