Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Baptiste Dupont"'
Autor:
Magalie Penaud-Budloo, Emilie Lecomte, Quentin Lecomte, Simon Pacouret, Frédéric Broucque, Aurélien Guy-Duché, Jean-Baptiste Dupont, Laurence Jeanson-Leh, Cécile Robin, Véronique Blouin, Eduard Ayuso, Oumeya Adjali
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101305- (2024)
With more than 130 clinical trials and 8 approved gene therapy products, adeno-associated virus (AAV) stands as one of the most popular vehicles to deliver therapeutic DNA in vivo. One critical quality attribute analyzed in AAV batches is the presenc
Externí odkaz:
https://doaj.org/article/042640a504cc42909af1d623d410fa67
Autor:
Martin Jeannerot, Morvan Ouisse, Vincent Lanfranchi, Jean‐Baptiste Dupont, Emeline Sadoulet‐Reboul
Publikováno v:
IET Electric Power Applications, Vol 15, Iss 12, Pp 1666-1677 (2021)
Abstract This study presents a sensitivity analysis methodology used for electric motor design. This innovative approach evaluates both global effects of parameter variations in their design range and of parameter deviations in their tolerance interv
Externí odkaz:
https://doaj.org/article/149c1699d2284790bdd8ec35b4a8600f
Autor:
Alec ST Smith, Shawn M Luttrell, Jean-Baptiste Dupont, Kevin Gray, Daniel Lih, Jacob W Fleming, Nathan J Cunningham, Sofia Jepson, Jennifer Hesson, Julie Mathieu, Lisa Maves, Bonnie J Berry, Elliot C Fisher, Nathan J Sniadecki, Nicholas A Geisse, David L Mack
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Engineered muscle tissues represent powerful tools for examining tissue level contractile properties of skeletal muscle. However, limitations in the throughput associated with standard analysis methods limit their utility for longitudinal study, high
Externí odkaz:
https://doaj.org/article/565ad4a21c544b2c9f25e7a2e203b886
Autor:
Virginie Mournetas, Emmanuelle Massouridès, Jean‐Baptiste Dupont, Etienne Kornobis, Hélène Polvèche, Margot Jarrige, Alan R.L. Dorval, Maxime R.F. Gosselin, Antigoni Manousopoulou, Spiros D. Garbis, Dariusz C. Górecki, Christian Pinset
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 209-232 (2021)
Abstract Background Duchenne muscular dystrophy (DMD) causes severe disability of children and death of young men, with an incidence of approximately 1/5000 male births. Symptoms appear in early childhood, with a diagnosis made mostly around 4 years
Externí odkaz:
https://doaj.org/article/ea187c682a4e4ab7b9410427b1c72de3
Autor:
Sonia, Assil, Pierre-Adrien, Bolze, Myriam, Boukhali, Carine, Cariou, Lise, Chauveau, Nicolas, Chuvin, Kévin, Dhondt, Antoine, Ducuing, Jean-Baptiste, Dupont, Clément, Grandin, Guillaume, Jarre, Juliette, Le Douce, Diane, Lebrun, Franc Ois-Xavier, Lechenet, Natascha, Luther, Milica, Milivojevic, Éléonore, Pérès, Émilie, Plantamura, Amélien, Sanlaville, Aurélien, Schwob, Maxime, Seggio, Jean-Emmanuel, Serre, Pierre-Alain, Thiébaut, Samantha, Tirmarche, Kizito-Tshitoko, Tshilenge, Céline, Vandamme, Pauline, Verlhac, Jennifer, Vinera, Renaud, Mahieux, Chloé, Journo
Publikováno v:
Virologie (Montrouge, France). 15(4)
Viruses represent an important cause of cancer in humans: infections are estimated to account for close to one cancer case out of five.With the ongoing discovery of new infectious agents, this number should be raising in the near future. In 2006, the
Terrorist attacks have nowadays become an important issue for the structural design of constructions such as bridges. Indeed, during the last decades, the increase in the number of terrorist attacks has resulted in the loss of many human lives and so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbf9a6dbcddbe1d747db45fbb1d36a5
https://hdl.handle.net/2078.1/265462
https://hdl.handle.net/2078.1/265462
Autor:
Emilie Lecomte, Benoît Tournaire, Benjamin Cogné, Jean-Baptiste Dupont, Pierre Lindenbaum, Mélanie Martin-Fontaine, Frédéric Broucque, Cécile Robin, Matthias Hebben, Otto-Wilhelm Merten, Véronique Blouin, Achille François, Richard Redon, Philippe Moullier, Adrien Léger
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 4, Iss C (2015)
Recent successful clinical trials with recombinant adeno-associated viral vectors (rAAVs) have led to a renewed interest in gene therapy. However, despite extensive developments to improve vector-manufacturing processes, undesirable DNA contaminants
Externí odkaz:
https://doaj.org/article/741f46340a074fda945084019638521d
Autor:
Jean-Baptiste Dupont, Benoit Tournaire, Christophe Georger, Béatrice Marolleau, Laurence Jeanson-Leh, Mireille Ledevin, Pierre Lindenbaum, Emilie Lecomte, Benjamin Cogné, Laurence Dubreil, Thibaut Larcher, Bernard Gjata, Laetitia Van Wittenberghe, Caroline Le Guiner, Magalie Penaud-Budloo, Richard O Snyder, Philippe Moullier, Adrien Léger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Preclinical gene therapy strategies using recombinant adeno-associated virus (AAV) vectors in animal models of Duchenne muscular dystrophy have shown dramatic phenotype improvements, but long-lasting efficacy remains questionable. It is believed that
Externí odkaz:
https://doaj.org/article/846a902b7ddb4553bb393762ce9f0d6f
Autor:
Jean-Baptiste Dupont
Publikováno v:
Molecular Therapy
Molecular Therapy, Cell Press, 2021, 29 (8), pp.2389-2390. ⟨10.1016/j.ymthe.2021.07.007⟩
Mol Ther
Molecular Therapy, Cell Press, 2021, 29 (8), pp.2389-2390. ⟨10.1016/j.ymthe.2021.07.007⟩
Mol Ther
Omics analyses are powerful methods to obtain an integrated view of complex biological processes, disease progression, or therapy efficiency. However, few studies have compared different disease forms and different therapy strategies to define the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01df3cb768cd334492a8ddd505ef0f4
https://www.hal.inserm.fr/inserm-03331174
https://www.hal.inserm.fr/inserm-03331174
Autor:
Céline Leteur, Margot Jarrige, Jérôme Polentes, Hélène Polvèche, Denis Furling, Cécile Martinat, Christian Pinset, Alexandre Carteron, Julie Tahraoui-Bories, Jean-Paul Concordet, Antoine Mérien, Michel Cailleret, Jean-Baptiste Dupont
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Human Molecular Genetics, 2022, 31 (1), pp.41-56. ⟨10.1093/hmg/ddab218⟩
Alternative splicing has emerged as a fundamental mechanism for the spatiotemporal control of development. A better understanding of how this mechanism is regulated has the potential not only to elucidate fundamental biological principles, but also t