Two unequally redundant 'helper' immune receptor families mediate Arabidopsis thaliana intracellular 'sensor' immune receptor functions.

Autor: Svenja C Saile, Pierre Jacob, Baptiste Castel, Lance M Jubic, Isai Salas-Gonzáles, Marcel Bäcker, Jonathan D G Jones, Jeffery L Dangl, Farid El Kasmi

Publikováno v: PLoS Biology, Vol 18, Iss 9, p e3000783 (2020)

Plant nucleotide-binding (NB) leucine-rich repeat (LRR) receptor (NLR) proteins function as intracellular immune receptors that perceive the presence of pathogen-derived virulence proteins (effectors) to induce immune responses. The 2 major types of

Externí odkaz: https://doaj.org/article/25740e6b33934ccf94e170740340136c

Generation of inheritable A-to-G transitions using adenine base editing and NG-PAM Cas9 in Arabidopsis thaliana

Autor: Yi Yun Tan, Yin Yin Liew, Baptiste Castel, Yizhong Zhang, Sang-Tae Kim, Eunyoung Chae

CRISPR/Cas9 technology is an important tool for functional genomics and crop improvement. It can be used to generate mutations at precise positions in the genome. Base editors consist of deaminase components and Cas9 to specify the type of mutation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1753d56a4b317f6b14711c3e97db4a17
https://doi.org/10.1101/2022.06.07.495175

Nucleocytoplasmic trafficking during immunity

Autor: Eunyoung Chae, Baptiste Castel

Publikováno v: Molecular plant. 14(10)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a69308d5f6cb711c749c7fd5c335383d
https://pubmed.ncbi.nlm.nih.gov/34400336

Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida recognition specificities

Autor: Shanshan Wang, Eric B. Holub, Baptiste Castel, Volkan Cevik, Oliver J. Furzer, Amey Redkar, Sebastian Fairhead, Jonathan D. G. Jones

SummaryThe oomycete Albugo candida causes white rust of Brassicaceae, including vegetable and oilseed crops, and wild relatives such as Arabidopsis thaliana. Novel White Rust Resistance (WRR)-genes from Arabidopsis enable new insights into plant/para

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb5a1afad32245cec760678efdd9a122
https://doi.org/10.1101/2021.03.29.437434

Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants

Autor: Zane Duxbury, Hailong Guo, Shanshan Wang, Maud Bernoux, Baptiste Castel, Xiaoxiao Zhang, Peter N. Dodds, Russell E. Vance, Jonathan D. G. Jones, Sung Un Huh, J. Chen, Pok N. Ngou, Pingtao Ding, Jeannette L. Tenthorey, Lanxi Hu, Yan Ma, Panagiotis N. Moschou, Craig MacKenzie, Lionel Hill

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (31), pp.18832-18839. ⟨10.1073/pnas.2001185117⟩
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (31), pp.18832-18839. ⟨10.1073/pnas.2001185117⟩

Significance Animal NLRs form wheel-like structures called inflammasomes upon perception of pathogen-associated molecules. The induced proximity of the signaling domains at the center of the wheel is hypothesized to recruit caspases for the first ste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97857fcafb402adca32a74778b9f318
https://pub.epsilon.slu.se/18742/