Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Baoyou Fan"'
Autor:
Ning Ran, Wenxiang Li, Renjie Zhang, Caorui Lin, Jianping Zhang, Zhijian Wei, Zonghao Li, Zhongze Yuan, Min Wang, Baoyou Fan, Wenyuan Shen, Xueying Li, Hengxing Zhou, Xue Yao, Xiaohong Kong, Shiqing Feng
Publikováno v:
Bioactive Materials, Vol 25, Iss , Pp 766-782 (2023)
Spinal cord injury (SCI) causes motor, sensory and automatic impairment due to rarely axon regeneration. Developing effective treatment for SCI in the clinic is extremely challenging because of the restrictive axonal regenerative ability and disconne
Externí odkaz:
https://doaj.org/article/57c6cf815e774e76a778eae999127c20
Autor:
Guangjin Gu, Bin Zhu, Jie Ren, Xiaomeng Song, Baoyou Fan, Han Ding, Jun Shang, Heng Wu, Junjin Li, Hongda Wang, Jinze Li, Zhijian Wei, Shiqing Feng
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Background Inflammatory response is an essential part of secondary injury after spinal cord injury (SCI). During this period, the injury may be exacerbated through the release of a large number of inflammatory factors and the polarization of
Externí odkaz:
https://doaj.org/article/9bab62fc345b40d997a40d9b8d0dcd83
Autor:
Wenxiang Li, Xiaoqing Zhao, Rong Zhang, Xinjie Liu, Zhangyang Qi, Yang Zhang, Weiqi Yang, Yilin Pang, Chenxi Zhao, Baoyou Fan, Ning Ran, Jiawei Zhang, Xiaohong Kong, Shiqing Feng, Xue Yao
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 11, Pp 2474-2481 (2023)
Maintaining the integrity of the blood-spinal cord barrier is critical for the recovery of spinal cord injury. Ferroptosis contributes to the pathogenesis of spinal cord injury. We hypothesized that ferroptosis is involved in disruption of the blood-
Externí odkaz:
https://doaj.org/article/8749af201fbd4db99fe00bece8f127f5
Autor:
Chenxi Zhao, Tiangang Zhou, Xiaoqing Zhao, Yilin Pang, Wenxiang Li, Baoyou Fan, Ming Li, Xinjie Liu, Lei Ma, Jiawei Zhang, Chao Sun, Wenyuan Shen, Xiaohong Kong, Xue Yao, Shiqing Feng
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Nafamostat mesylate (nafamostat, NM) is an FDA-approved serine protease inhibitor that exerts anti-neuroinflammation and neuroprotective effects following rat spinal cord injury (SCI). However, clinical translation of nafamostat h
Externí odkaz:
https://doaj.org/article/94572d5f6dff451bb1df2e908584aad4
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-26 (2022)
Abstract Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level and imposes a considerable burden on patients, families, and society. Repair of the injured spinal cord has been recognized as a global medical chall
Externí odkaz:
https://doaj.org/article/814e48888119479abbad5d43b5daa6c3
Publikováno v:
Journal of Orthopaedic Translation, Vol 31, Iss , Pp 33-40 (2021)
Spinal cord injury (SCI) is a disastrous situation that affects many patients worldwide. A profound understanding of the pathology and etiology of SCI is of great importance in inspiring new therapeutic concepts and treatment. In recent years, exosom
Externí odkaz:
https://doaj.org/article/a1f0efeec9c24935bab0a5063232f309
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
N6-methyladenosine (m6A), an essential post-transcriptional modification in eukaryotes, is closely related to the development of pathological processes in neurological diseases. Notably, spinal cord injury (SCI) is a serious traumatic disease of the
Externí odkaz:
https://doaj.org/article/49e3b20640c54e54b06de7f6ee7bc348
Autor:
Xue Yao, Chao Sun, Baoyou Fan, Chenxi Zhao, Yan Zhang, Huiquan Duan, Yilin Pang, Wenyuan Shen, Bo Li, Xu Wang, Chang Liu, Hengxing Zhou, Xiaohong Kong, Shiqing Feng
Publikováno v:
Journal of Orthopaedic Translation, Vol 26, Iss , Pp 74-83 (2021)
Background/objective: Spinal cord injury (SCI) severely and irreversibly damages the central nervous system. Neurotropin (NTP), a nonprotein extract obtained from inflamed rabbit skin inoculated with vaccinia virus, is a drug that has been used for m
Externí odkaz:
https://doaj.org/article/3e539d40df0449e786716d0ce3b7ddd8
Autor:
Yilin Pang, Xinjie Liu, Xu Wang, Xuelian Shi, Lei Ma, Yan Zhang, Tiangang Zhou, Chenxi Zhao, Xu Zhang, Baoyou Fan, Jian Hao, Wenxiang Li, Xiaoqing Zhao, Rong Zhang, Songlin Zhou, Xiaohong Kong, Shiqing Feng, Xue Yao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The FDA-approved drug edaravone has a neuroprotective effect on spinal cord injury (SCI) and many other central nervous system diseases. However, its molecular mechanism remains unclear. Since edaravone is a lipid peroxidation scavenger, we hypothesi
Externí odkaz:
https://doaj.org/article/363bfdce926d45d6a8d5a997ba3d3780
Autor:
Baoyou Fan, Zhijian Wei, Xue Yao, Guidong Shi, Xin Cheng, Xianhu Zhou, Hengxing Zhou, Guangzhi Ning, Xiaohong Kong, Shiqing Feng
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Spinal cord injury (SCI), for which there currently is no cure, is a heavy burden on patient physiology and psychology. The microenvironment of the injured spinal cord is complicated. According to our previous work and the advancements in SCI researc
Externí odkaz:
https://doaj.org/article/3e596153fdde4d1398cadaca30702f3a