Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Baoxi Zhang"'
Autor:
Zhipeng Wang, Qi Li, Qi An, Lixiang Gong, Shiying Yang, Baoxi Zhang, Bin Su, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du
Publikováno v:
Natural Products and Bioprospecting, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract With various potential health-promoting bioactivities, genistein has great prospects in treatment of a series of complex diseases and metabolic syndromes such as cancer, diabetes, cardiovascular diseases, menopausal symptoms and so on. Howev
Externí odkaz:
https://doaj.org/article/81ba1ca4e0d847b2aa6525e1d3b7c3e1
Autor:
Yifei Xie, Lixiang Gong, Yue Tao, Baoxi Zhang, Li Zhang, Shiying Yang, Dezhi Yang, Yang Lu, Guanhua Du
Publikováno v:
Molecules, Vol 29, Iss 10, p 2208 (2024)
Ligustrazine (TMP) is the main active ingredient extracted from Rhizoma Chuanxiong, which is used in the treatment of cardiovascular and cerebrovascular diseases, with the drawback of being unstable and readily sublimated. Cocrystal technology is an
Externí odkaz:
https://doaj.org/article/cb0039b07ad1435bb1b6ab979511cbe5
Autor:
Yeyang Wang, Baoxi Zhang, Wenwen Wang, Penghui Yuan, Kun Hu, Li Zhang, Dezhi Yang, Yang Lu, Guanhua Du
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 94 (2024)
Matrine (MAT), a natural Chinese herbal medicine, has a unique advantage in the treatment of various chronic diseases. However, its low melting point, low bioavailability, and high dosage restrict its subsequent development into new drugs. In this st
Externí odkaz:
https://doaj.org/article/2dea8402691f4905a1dfad78deab4c90
Publikováno v:
ACS Omega, Vol 7, Iss 10, Pp 8906-8918 (2022)
Externí odkaz:
https://doaj.org/article/7dba008a35094527957a76fd980e881e
Autor:
Hongmei Yu, Li Zhang, Meiju Liu, Dezhi Yang, Guorong He, Baoxi Zhang, Ningbo Gong, Yang Lu, Guanhua Du
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1349 (2023)
To improve the solubility and dissolution rate of the BCS class II drug ketoconazole, five novel solid forms in 1:1 stoichiometry were obtained upon liquid-assisted grinding, slurry, and slow evaporation methods in the presence of coformers, namely,
Externí odkaz:
https://doaj.org/article/c63d37ab872c4141bc815a9061de98a8
Autor:
Mingchao Yu, Meidai Liang, Qi An, Wenwen Wang, Baoxi Zhang, Shiying Yang, Jian Zhou, Xiuying Yang, Dezhi Yang, Li Zhang, Guanhua Du, Yang Lu
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1196 (2023)
This study aimed to develop an effective treatment for diabetes and diabetic complications, based on the advantage complementary strategy of drug–drug salt, by designing and synthesizing the multicomponent molecular salts containing metformin (MET)
Externí odkaz:
https://doaj.org/article/803d75d149c44855864d411b5932726f
Publikováno v:
Natural Products and Bioprospecting, Vol 10, Iss 4, Pp 187-200 (2020)
Abstract Mangiferin is a compound with many pharmacological activities and exists in many natural products. Anhydrous and hydrate of mangiferin have been reported separately in two literatures, but the polymorphism of this compound has not been reali
Externí odkaz:
https://doaj.org/article/25f5b732fb7e4bf2b3f9f718d993270b
Autor:
Yuanyuan Zhao, Yiwei Liu, Zhenghai Zhang, Yacong Cao, Hailong Yu, Wenwen Ma, Baoxi Zhang, Risheng Wang, Jie Gao, Lihao Wang
Publikováno v:
BMC Plant Biology, Vol 20, Iss 1, Pp 1-8 (2020)
Abstract Background Colletotrichum species are the causal agents of anthracnose, a major disease affecting the yield and quality of pepper (Capsicum spp.). Colletotrichum scovillei is widespread in China, has strong pathogenicity and drug resistance,
Externí odkaz:
https://doaj.org/article/0a61ab3e65c547dcaaa2d510a0ac7e57
Publikováno v:
Natural Products and Bioprospecting, Vol 10, Iss 2, Pp 67-75 (2020)
Abstract Salvianolic acid A (Sal A), a water-soluble ingredient in Danshen, has various biological activities. Sal A and its impurities have similar physical and chemical properties, as well as strong reducibility; therefore, they are difficult to pr
Externí odkaz:
https://doaj.org/article/e3f20d58bd324bfa95c1d81815e43dc6
Autor:
Hongmei Yu, Baoxi Zhang, Meiju Liu, Wenhui Xing, Kun Hu, Shiying Yang, Guorong He, Ningbo Gong, Guanhua Du, Yang Lu
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2486 (2022)
To modulate the physicochemical properties of fluconazole (FLZ), a multifunctional antifungal drug, the crystal engineering technique was employed. In this paper, five novel cocrystal hydrates of FLZ with a range of phenolic acids from the GRAS list,
Externí odkaz:
https://doaj.org/article/e8f394c080e648408712321f46210db3