Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Baosheng Chen"'
Autor:
Chao Zheng, Takuya Toyonaga, Baosheng Chen, LaShae Nicholson, William Mennie, Michael Liu, Joshua Spurrier, Kristin Deluca, Stephen M. Strittmatter, Richard E. Carson, Yiyun Huang, Zhengxin Cai
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionSynapse loss is one of the hallmarks of Alzheimer's disease (AD) and is associated with cognitive decline. In this study, we tested [18F]SDM-16, a novel metabolically stable SV2A PET imaging probe, in the transgenic APPswe/PS1dE9 (APP/PS1
Externí odkaz:
https://doaj.org/article/8e0dd44d63344551bb7b3a0f877d6b96
Autor:
Jishui Zhang, Wenhao Lv, Yagang Liu, Weihua Fu, Baosheng Chen, Qiutong Ma, Xin Gao, Xiuxia Cui
Publikováno v:
Balkan Medical Journal, Vol 38, Iss 6, Pp 331-340 (2021)
Externí odkaz:
https://doaj.org/article/0f2fa1ab94d4403fa74289f21afd6937
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Poly (ADP-ribose) polymerases (PARPs) constitute of 17 members that are associated with divergent cellular processes and play a crucial role in DNA repair, chromatin organization, genome integrity, apoptosis, and inflammation. Multiple lines of evide
Externí odkaz:
https://doaj.org/article/a61caba4081d44d7831f539705decd51
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Long non-coding RNAs exert vital roles in several types of cancer. The objective of this study was to explore the role of LINC_00355 in gastric cancer (GC) progression and its potential mechanism. Methods The expression levels of
Externí odkaz:
https://doaj.org/article/74bd1660d15b4d76a2f22bdb96c45461
Autor:
Baosheng Chen, Bernadette Marquez-Nostra, Erika Belitzky, Takuya Toyonaga, Jie Tong, Yiyun Huang, Zhengxin Cai
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The successful development and translation of PET imaging agents targeting β-amyloid plaques and hyperphosphorylated tau tangles have allowed for in vivo detection of these hallmarks of Alzheimer’s disease (AD) antemortem. Amyloid and tau PET have
Externí odkaz:
https://doaj.org/article/b7ce46781f354419a7158f69d0a251aa
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3434-3442 (2010)
The previous studies in our laboratory revealed that seven cysteine mutants of apolipoprotein A-I (apoA-I) have different structural features and biological activities in vitro and in vivo. To investigate the potential cardioprotective effects of apo
Externí odkaz:
https://doaj.org/article/b3e3242cd89645538cf64f849134e4c2
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 8, Pp 1640-1645 (2008)
HDL has been shown to be able to neutralize the toxicity of lipopolysaccharide (LPS). Our previous study (J. Lipid Res. 2005. 46: 1303–1311) characterized the properties of secondary structure and in vitro functions of different cysteine mutants of
Externí odkaz:
https://doaj.org/article/317a7afdbf92476aa86359c0b45f71db
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 6, Pp 1303-1311 (2005)
Apolipoprotein A-IMilano (A-IM) (R173C), a natural mutant of human apolipoprotein A-I (apoA-I), and five other cysteine variants of apoA-I at residues 52 (S52C), 74 (N74C), 107 (K107C), 129 (G129C), and 195 (K195C) were generated. Cysteine residues w
Externí odkaz:
https://doaj.org/article/54a3afd5843f452b9c86f02ca1c61c2f
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75473 (2013)
The protein N-Myc downstream-regulated gene 1 (NDRG1) is implicated in the regulation of cell proliferation, differentiation, and cellular stress response. NDRG1 is expressed in primary human trophoblasts, where it promotes cell viability and resista
Externí odkaz:
https://doaj.org/article/344514a853374a408a375a8ad1ceff1c
Autor:
Yunlong Wang, Shulai Lu, Xinde Li, Na Du, Yunbo Sun, Jinyan Xing, Xinting Pan, Baosheng Chen, Zhimin Miao
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51327 (2012)
Our previous studies showed that recombinant high-density lipoprotein (rHDL) rHDL74 exhibited higher anti-inflammatory capabilities compared to wild-type rHDL (rHDLwt), while rHDL228 showed hyper-proinflammation. In this paper, we further investigate
Externí odkaz:
https://doaj.org/article/4d396d9e520745528d3fa2314694bd3b