Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Baoli Hu"'
Publikováno v:
Toxics, Vol 12, Iss 6, p 419 (2024)
Arsenic (As) contamination of surface water has become a global concern, especially for the third world countries, and it is imperative to develop advanced materials and an effective treatment method to address the issue. In this paper, iron doped ZI
Externí odkaz:
https://doaj.org/article/90fee9a96013446988c6a8abfc64bc6b
Autor:
Sanjay K. Singh, Yan Wang, Ahmed Habib, Mamindla Priyadarshini, Chowdari V. Kodavali, Apeng Chen, Wencai Ma, Jing Wang, N. U. Farrukh Hameed, Baoli Hu, Gregory N. Fuller, Scott M. Kulich, Nduka Amankulor, Rivka R. Colen, Lincoln A. Edwards, Pascal O. Zinn
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Glioblastoma (GBM) is fatal and the study of therapeutic resistance, disease progression, and drug discovery in GBM or glioma stem cells is often hindered by limited resources. This limitation slows down progress in both drug discovery and patient su
Externí odkaz:
https://doaj.org/article/14b70cbfdcae49adb6619b89be2df058
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102049- (2023)
Summary: Understanding the glioblastoma (GBM) immune microenvironment and development of clinical treatment drugs rely on suitable preclinical GBM models. Here, we present a protocol to establish syngeneic orthotopic glioma mouse models. We also desc
Externí odkaz:
https://doaj.org/article/3c206ee7b98a469e817eea6b1b057479
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Gliomas have an extremely poor prognosis in both adult and pediatric patient populations as these tumors are known to grow aggressively and respond poorly to standard of care treatment. Currently, treatment for gliomas involves surgical resection fol
Externí odkaz:
https://doaj.org/article/f97bc495a12d459e9499e56fd4c3e8aa
Autor:
Deepavali Chakravarti, Baoli Hu, Xizeng Mao, Asif Rashid, Jiexi Li, Jun Li, Wen-ting Liao, Elizabeth M. Whitley, Prasenjit Dey, Pingping Hou, Kyle A. LaBella, Andrew Chang, Guocan Wang, Denise J. Spring, Pingna Deng, Di Zhao, Xin Liang, Zhengdao Lan, Yiyun Lin, Sharmistha Sarkar, Christopher Terranova, Yonathan Lissanu Deribe, Sarah E. Blutt, Pablo Okhuysen, Jianhua Zhang, Eduardo Vilar, Ole Haagen Nielsen, Andrew Dupont, Mamoun Younes, Kalyani R. Patel, Noah F. Shroyer, Kunal Rai, Mary K. Estes, Y. Alan Wang, Alison A. Bertuch, Ronald A. DePinho
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
How telomere dysfunction is directly linked to inflammation in humans is currently unclear. Here the authors reveal that telomere dysfunction drives activation of the YAP1 transcription factor, up-regulating the pro inflammatory factor, pro-IL-18 thu
Externí odkaz:
https://doaj.org/article/b5a35bee98a746039f8bae5793248657
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 4284-4292 (2019)
LncRNA LINC01518 was previously reported to be upregulated in oesophageal squamous cell carcinoma (ESCC) tissues compared with normal tissues. However, there are no previous studies concerning the specific function and molecular mechanism of LINC0151
Externí odkaz:
https://doaj.org/article/5314954ddc1a4021ae6a137b151b9b5c
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 47, Iss 1, Pp 3410-3416 (2019)
Background Non-small-cell lung carcinoma (NSCLC) is the most common type of lung cancer. Circular RNA ZFR (circZFR) is an identified circular RNA (circRNA) that is correlated with cancer progression. However, the role of circZFR in NSCLC remains unkn
Externí odkaz:
https://doaj.org/article/e8861be776894f38a52b78a187a6c7d8
Autor:
Zhuolun Shen, Yufei Xiang, Sandra Vergara, Apeng Chen, Zhengyun Xiao, Ulises Santiago, Changzhong Jin, Zhe Sang, Jiadi Luo, Kong Chen, Dina Schneidman-Duhovny, Carlos Camacho, Guillermo Calero, Baoli Hu, Yi Shi
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103014- (2021)
Summary: Therapeutic and diagnostic efficacies of small biomolecules and chemical compounds are hampered by suboptimal pharmacokinetics. Here, we developed a repertoire of robust and high-affinity antihuman serum albumin nanobodies (NbHSA) that can b
Externí odkaz:
https://doaj.org/article/e246d8f7b3d242118398e3256a1ec787
Autor:
Itay Raphael, Rajeev Kumar, Lauren H. McCarl, Karsen Shoger, Lin Wang, Poorva Sandlesh, Chaim T. Sneiderman, Jordan Allen, Shuyan Zhai, Marissa Lynn Campagna, Alexandra Foster, Tullia C. Bruno, Sameer Agnihotri, Baoli Hu, Brandyn A. Castro, Frank S. Lieberman, Alberto Broniscer, Aaron A. Diaz, Nduka M. Amankulor, Dhivyaa Rajasundaram, Ian F. Pollack, Gary Kohanbash
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glioblastoma (GBM) remains an aggressive brain tumor with a high rate of mortality. Immune checkpoint (IC) molecules are expressed on tumor infiltrating lymphocytes (TILs) and promote T cell exhaustion upon binding to IC ligands expressed by the tumo
Externí odkaz:
https://doaj.org/article/aec74bbb1c6b4bd1b658f3f136f5b61d
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Cancer is a disease mainly caused by somatic genome alterations (SGAs) that perturb cellular signalling systems. Furthermore, the combination of pathway aberrations in a tumour defines its disease mechanism, and distinct disease mechanisms u
Externí odkaz:
https://doaj.org/article/edd3506aa54e4a72847c9a111af4d6ee