Zobrazeno 1 - 10 of 514 pro vyhledávání: '"Baohua Gu"'
1
Akademický článek
The effects of Fc fusion protein glucagon-like peptide-1 and glucagon dual receptor agonist with different receptor selectivity in vivo studies
Autor: Peng Jiang, Ying Zeng, Wen Yang, Lijia Li, Linjun Zhou, Lin Xiao, Yong Li, Baohua Gu, Xiaoping Li, Jing Li, Wenjia Li, Linfeng Guo
Publikováno v: Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116485- (2024)
Background: Glucagon-like peptide-1 (GLP-1)/glucagon (GCG) dual receptor agonists with different receptor selectivity are under investigation and have shown significant improvement in both weight loss and glycemic control, but the optimal potency rat
Externí odkaz: https://doaj.org/article/21f59b07d324420e89ec620439353ab1
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2
Akademický článek
DemethylationThe Other Side of the Mercury Methylation Coin: A Critical Review
Autor: Tamar Barkay, Baohua Gu
Publikováno v: ACS Environmental Au, Vol 2, Iss 2, Pp 77-97 (2021)
Externí odkaz: https://doaj.org/article/032ff0c636b0451b8caf55f217771e5a
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3
Akademický článek
Long-term warming in a Mediterranean-type grassland affects soil bacterial functional potential but not bacterial taxonomic composition
Autor: Ying Gao, Junjun Ding, Mengting Yuan, Nona Chiariello, Kathryn Docherty, Chris Field, Qun Gao, Baohua Gu, Jessica Gutknecht, Bruce A. Hungate, Xavier Le Roux, Audrey Niboyet, Qi Qi, Zhou Shi, Jizhong Zhou, Yunfeng Yang
Publikováno v: npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Climate warming is known to impact ecosystem composition and functioning. However, it remains largely unclear how soil microbial communities respond to long-term, moderate warming. In this study, we used Illumina sequencing and microarrays (
Externí odkaz: https://doaj.org/article/2130ba16ccb64cbabf95e5d7bd86d5ff
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4
Akademický článek
Mechanistic Modeling of Microtopographic Impacts on CO2 and CH4 Fluxes in an Alaskan Tundra Ecosystem Using the CLM‐Microbe Model
Autor: Yihui Wang, Fengming Yuan, Fenghui Yuan, Baohua Gu, Melanie S. Hahn, Margaret S. Torn, Daniel M. Ricciuto, Jitendra Kumar, Liyuan He, Donatella Zona, David A. Lipson, Robert Wagner, Walter C. Oechel, Stan D. Wullschleger, Peter E. Thornton, Xiaofeng Xu
Publikováno v: Journal of Advances in Modeling Earth Systems, Vol 11, Iss 12, Pp 4288-4304 (2019)
Abstract Spatial heterogeneities in soil hydrology have been confirmed as a key control on CO2 and CH4 fluxes in the Arctic tundra ecosystem. In this study, we applied a mechanistic ecosystem model, CLM‐Microbe, to examine the microtopographic impa
Externí odkaz: https://doaj.org/article/dfa8c097fba54973bd3e4fac7df54323
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7
Akademický článek
Temporal, Spatial, and Temperature Controls on Organic Carbon Mineralization and Methanogenesis in Arctic High-Centered Polygon Soils
Autor: Taniya Roy Chowdhury, Erin C. Berns, Ji-Won Moon, Baohua Gu, Liyuan Liang, Stan D. Wullschleger, David E. Graham
Publikováno v: Frontiers in Microbiology, Vol 11 (2021)
Warming temperatures in continuous permafrost zones of the Arctic will alter both hydrological and geochemical soil conditions, which are strongly linked with heterotrophic microbial carbon (C) cycling. Heterogeneous permafrost landscapes are often d
Externí odkaz: https://doaj.org/article/2d631d0664b5432083b4011cfa1750f5
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8
Akademický článek
A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis
Autor: Qi Pan, Shushan Lin, Yu Li, Liang Liu, Xiaoping Li, Xianglei Gao, Jiangyu Yan, Baohua Gu, Xiaofeng Chen, Wenjia Li, Xinfa Tang, Chao Chen, Lixin Guo
Publikováno v: EBioMedicine, Vol 63, Iss , Pp 103202- (2021)
Background: Fibroblast growth factor 21 (FGF21) has become a promising therapeutic target for metabolic diseases such as type 2 diabetes (T2D), obesity and non-alcoholic steatohepatitis. However, the clinical application of natural FGF21 molecule is
Externí odkaz: https://doaj.org/article/7e596c8625a2436db136e1239e8fa2dd
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