Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Baohu Ji"'
Autor:
Layne N. Rodden, Christian Rummey, Yi Na Dong, Sarah Lagedrost, Sean Regner, Alicia Brocht, Khalaf Bushara, Martin B. Delatycki, Christopher M. Gomez, Katherine Mathews, Sarah Murray, Susan Perlman, Bernard Ravina, S. H. Subramony, George Wilmot, Theresa Zesiewicz, Alessandra Bolotta, Alain Domissy, Christine Jespersen, Baohu Ji, Elisabetta Soragni, Joel M. Gottesfeld, David R. Lynch
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Introduction: Friedreich ataxia (FRDA) is a recessive neurodegenerative disease characterized by progressive ataxia, dyscoordination, and loss of vision. The variable length of the pathogenic GAA triplet repeat expansion in the FXN gene in part expla
Externí odkaz:
https://doaj.org/article/fc3b8365f48643339b44ac26a1d1ebf4
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 909-918 (2015)
Background: Psychiatric disorders are common mental disorders without a pathological biomarker. Classic genetic studies found that an extra X chromosome frequently causes psychiatric symptoms in patients with either Klinefelter syndrome (XXY) or Trip
Externí odkaz:
https://doaj.org/article/0610770e644e42a080924c889dfba8ca
Publikováno v:
PeerJ, Vol 5, p e3905 (2017)
Small interference RNA has been widely used to suppress gene expression. Three different short hairpin RNAs (shRNAs) against dopamine D1 receptor (Drd1), driven by mouse U6 promoter in self-complementary AAV8 vector (scAAV8), were used to silence mou
Externí odkaz:
https://doaj.org/article/7c1deccb23d34e69a80903ef822ef8d4
Autor:
Xudong Liu, Linghan Gao, Aman Zhao, Rui Zhang, Baohu Ji, Lei Wang, Yonglan Zheng, Bingfang Zeng, Robert K Valenzuela, Lin He, Jie Ma
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94201 (2014)
Brachydactyly type A2 (BDA2, MIM 112600) is characterized by the deviation and shortening of the middle phalange of the index finger and the second toe. Using genome-wide linkage analysis in a Chinese BDA2 family, we mapped the maximum candidate inte
Externí odkaz:
https://doaj.org/article/64c91133def34476980aeea02e673a1a
Autor:
Baohu Ji, Xin Wang, Antonio Pinto-Duarte, Minjung Kim, Sorana Caldwell, Jared W Young, Margarita M Behrens, Terrence J Sejnowski, Mark A Geyer, Xianjin Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66327 (2013)
It has been well established that schizophrenia patients display impaired NMDA receptor (NMDAR) functions as well as exacerbation of symptoms in response to NMDAR antagonists. Abnormal NMDAR signaling presumably contributes to cognitive deficits whic
Externí odkaz:
https://doaj.org/article/77e8d804cf70467182373a88e38469a2
Autor:
Liya Sun, Juan Li, Kejun Zhou, Ming Zhang, Jinglei Yang, Yang Li, Baohu Ji, Zhao Zhang, Hui Zhu, Lun Yang, Guang He, Linghan Gao, Zhiyun Wei, Kejian Wang, Xue Han, Weiqing Liu, Liwen Tan, Yihua Yu, Lin He, Chunling Wan
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60598 (2013)
BACKGROUND: Although a number of proteins and genes relevant to schizophrenia have been identified in recent years, few are known about the exact metabolic pathway involved in this disease. Our previous proteomic study has revealed the energy metabol
Externí odkaz:
https://doaj.org/article/aa9e1a9497f34f0a9976ceb949407917
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32043 (2012)
The analysis of co-localized protein expression in a tissue section is often conducted with immunofluorescence histochemical staining which is typically visualized in localized regions. On the other hand, chromogenic immunohistochemical staining, in
Externí odkaz:
https://doaj.org/article/1c9169d2654645ea953feb30cc22b721
Autor:
Xianjin Zhou, Jared W. Young, Baohu Ji, Jordy van Enkhuizen, Benjamin Z Roberts, Molly A. Kwiatkowski
Publikováno v:
Eur Neuropsychopharmacol
Bipolar disorder (BD) is a severe mental illness affecting 2% of the global population. Current pharmacotherapies provide incomplete symptom remediation, highlighting the need for novel therapeutics. BD is characterized by fluctuations between mania
Publikováno v:
Behavioural Brain Research. 323:100-110
Dopamine (DA) is required for reinforcement learning. Hence, disruptions in DA signaling may contribute to the learning deficits associated with psychiatric disorders. The DA D1 receptor (D1R) has been linked to learning and is a target for cognitive
Autor:
Rui Zhang, Shemin Lu, James V. Luck, John R. Kelsoe, Jianfeng Yao, Brian Chin, Baohu Ji, Jie Ma, Peng Xu
Publikováno v:
Inflammation Research. 64:405-414
A number of studies have reported an association of GDF5 with osteoarthritis (OA) but have produced some divergent findings and their interpretation may not be straightforward.We investigated the association between GDF5 and OA using meta-analytic te