Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Baohe Guan"'
Publikováno v:
Organicbiomolecular chemistry. 18(48)
(-)-Homo-renieramycin G and its twenty derivatives were prepared from l-tyrosine methyl ester via a multi-step route. Their cytotoxicities were tested against four human cancer cell lines (A549, HeLa, KB and BGC-823). (-)-Renieramycin G and (-)-homo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e9dd81c26c4b9dcd064c947fc144eb1
https://pubmed.ncbi.nlm.nih.gov/33300542
https://pubmed.ncbi.nlm.nih.gov/33300542
Publikováno v:
Tetrahedron Letters. 59:3029-3032
A novel and facile synthesis of l -5-hydroxy-2,4-methoxy-3-methylphenylalanine derivatives, which are the key coupling partners for the asymmetric total synthesis of natural bistetrahydroisoquinoline alkaloids, is realized starting from l -tyrosine w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::080647f8125a2daf5740149292b30e31
https://doi.org/10.1016/j.tetlet.2018.07.003
https://doi.org/10.1016/j.tetlet.2018.07.003
Publikováno v:
Organicbiomolecular chemistry. 18(2)
Two series of novel hexacyclic skeletons and their thirty-four derivatives were prepared from l-tryptophan and l-DOPA. The cytotoxicities of these compounds were tested against four human cancer cell lines HCT-116, HepG2, BGC-823 and A2780. Compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be486d45f18a4be9045da6c79d87b07
https://pubmed.ncbi.nlm.nih.gov/31782476
https://pubmed.ncbi.nlm.nih.gov/31782476
Publikováno v:
Tetrahedron. 72:4346-4354
The total synthesis of (±)-parthenolide and (±)-7-epi-parthenolide starting from readily available limonene has been achieved with high stereoselectivity. The key synthetic features include (i) a ring expansion reaction, Oxy-Cope rearrangement to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::949ae262ed31358574e5c39a174d17d7
https://doi.org/10.1016/j.tet.2016.05.074
https://doi.org/10.1016/j.tet.2016.05.074
Publikováno v:
Tetrahedron. 71:4296-4303
(−)-Renieramycin G, a marine antitumor natural product, is a typical member of the bis-tetrahydroisoquinoline alkaloid family. In this paper, an efficient protocol of asymmetric total synthesis of its three stereoisomers, (+)-renieramycin G, 11,13-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9186b71dc584f0cbeff39dfe9cc92cc3
https://doi.org/10.1016/j.tet.2015.04.064
https://doi.org/10.1016/j.tet.2015.04.064
Publikováno v:
ChemInform. 43
A series of (-)-saframycin A analogues (I) are prepared from L-tyrosine in 24 steps and evaluated for their in vitro cytotoxicity against a panel of ten human tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5af148421420c38d697e4c987531c94d
https://doi.org/10.1002/chin.201230221
https://doi.org/10.1002/chin.201230221
Publikováno v:
European journal of medicinal chemistry. 49
(-)-Saframycin A and its nineteen analogues were prepared from L-tyrosine in 24 steps, and their structures were confirmed through NMR and HRMS. The cytotoxicities of these compounds were tested against HCT-8, BEL-7402, Ketr3, A2780, MCF-7, A549, BGC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a63f4fc6f80ba1e3e29b243bc826202
https://pubmed.ncbi.nlm.nih.gov/22284268
https://pubmed.ncbi.nlm.nih.gov/22284268
Publikováno v:
The Journal of organic chemistry. 76(13)
The asymmetric total synthesis of (−)-saframycin A, a natural antitumor product of the tetrahydroisoquinoline antitumor antibiotics family, has been accomplished by employing l-tyrosine as the starting chiral building block in 24 steps for the long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7b5f94e088645d70378a7905d33112e
https://pubmed.ncbi.nlm.nih.gov/21612294
https://pubmed.ncbi.nlm.nih.gov/21612294
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(5)
(−)-Renieramycin G and fifteen C-22 analogs were prepared employing l -tyrosine as the chiral starting material. These analogs, along with (−)-renieramycin G itself, were evaluated in vitro for cytotoxicity against HCT-8, BEL-7402, A2780, MCF-7,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecbf2b3a3bfd753f4b079857c5ad441
https://pubmed.ncbi.nlm.nih.gov/21295980
https://pubmed.ncbi.nlm.nih.gov/21295980