Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Baofeng Lian"'
Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma
Autor:
Xu Yang, Baofeng Lian, Nan Zhang, Junyu Long, Yiran Li, Jingnan Xue, Xiangqi Chen, Yunchao Wang, Yanyu Wang, Ziyu Xun, Mingjian Piao, Chenpei Zhu, Shanshan Wang, Huishan Sun, Zhijian Song, Leilei Lu, Xiaowei Dong, Aodi Wang, Wenjin Liu, Jie Pan, Xiaorong Hou, Mei Guan, Li Huo, Jie Shi, Haohai Zhang, Jinxue Zhou, Zhenhui Lu, Yilei Mao, Xinting Sang, Liqun Wu, Xiaobo Yang, Kai Wang, Haitao Zhao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Microsatellite instability-high (MSI-H) is a unique genomic status in many cancers. However, its role in the genomic features and immunotherapy in cholangiocarcinoma (CCA) is unclear. This study aimed to systematically investigate
Externí odkaz:
https://doaj.org/article/e96e78be7cfb426197e9dec8e4c18944
Autor:
Mengxuan Zhu, Erbao Chen, Shan Yu, Chen Xu, Yiyi Yu, Xin Cao, Wei Li, Pengfei Zhang, Yan Wang, Baofeng Lian, Shuirong Zhang, Yueting Qu, Lujia Huang, Weiwei Shi, Yuehong Cui, Li Qian, Tianshu Liu
Publikováno v:
Cancer Communications, Vol 42, Iss 10, Pp 1032-1035 (2022)
Externí odkaz:
https://doaj.org/article/55f6bdecef79400b8d7d9d59896349ec
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Diabetic nephropathy (DN) affects about 40% of diabetes mellitus (DM) patients and is the leading cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) all over the world, especially in high- and middle-income c
Externí odkaz:
https://doaj.org/article/e1674ed7ea50403ca604d0f69f4bb078
Autor:
Wei Li, Jian Yu, Baofeng Lian, Han Sun, Jing Li, Menghuan Zhang, Ling Li, Yixue Li, Qian Liu, Lu Xie
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118672 (2015)
Traditionally top-down method was used to identify prognostic features in cancer research. That is to say, differentially expressed genes usually in cancer versus normal were identified to see if they possess survival prediction power. The problem is
Externí odkaz:
https://doaj.org/article/18391823e6ca41fc9290afe73caeccd0
Autor:
Shuyuan Wang, Wei Li, Baofeng Lian, Xinyi Liu, Yan Zhang, Enyu Dai, Xuexin Yu, Fanlin Meng, Wei Jiang, Xia Li
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125222 (2015)
Over the past decades, studies have reported that the combinatorial regulation of transcription factors (TFs) and microRNAs (miRNAs) is essential for the appropriate execution of biological events and developmental processes. Dysregulations of these
Externí odkaz:
https://doaj.org/article/8ae7e4f6ef8b4b89a0325ff794c9789d
Autor:
Yuannv Zhang, Zhaoping Qiu, Lin Wei, Ruqi Tang, Baofeng Lian, Yingjun Zhao, Xianghuo He, Lu Xie
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100854 (2014)
BACKGROUND: Recently, a number of studies have performed genome or exome sequencing of hepatocellular carcinoma (HCC) and identified hundreds or even thousands of mutations in protein-coding genes. However, these studies have only focused on a limite
Externí odkaz:
https://doaj.org/article/d05075f4918043b08c9793edbe0716c9
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98653 (2014)
BACKGROUND: Transcriptional regulatory network (TRN) is used to study conditional regulatory relationships between transcriptional factors and genes. However few studies have tried to integrate genomic variation information such as copy number variat
Externí odkaz:
https://doaj.org/article/926c6739a77643c4abc1449c20daa5eb
Autor:
Xu Yang, Baofeng Lian, Yiran Li, Jinnan Xue, Yunchao Wang, Yanyu Wang, Ziyu Xun, Nan Zhang, Huishan Sun, Junyu Long, Zhijian Song, Leilei Lu, Jie Pan, Lin Zhao, Mei Guan, Xiaobo Yang, Yilei Mao, Xinting Sang, Kai Wang, Hai-Tao Zhao
Publikováno v:
Journal of Clinical Oncology. 40:4101-4101
4101 Background: Microsatellite instability-high (MSI-H) status is a unique genomic state with encouraging effects of PD-1-based therapy in patients with advanced cancer. Cholangiocarcinoma is often driven by genetic mutations. However, the genomic c
Autor:
Hao Zeng, Xuejing Zhong, Wenxin Liu, Baofeng Liang, Xueyi Xue, Nong Yu, Dongbo Xu, Xiaojie Wang, Shuangming Lin
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeThe aim to assess treatment failure in patients with stage III colon cancer who underwent radical surgery and was analyzed using the nomogram.MethodsClinical factors and survival outcomes for stage III colon cancer patients registered in the S
Externí odkaz:
https://doaj.org/article/3bff8e1a54d24f5d8544701adce30872
Autor:
Jing Gao, Wenwen Huang, Hui Feng, Cheng Zhang, Kai Wang, Sai Ge, Weiwei Shi, Zhongwu Li, Songhui Zhao, Jiafu Ji, Rui-Hua Xu, Baofeng Lian, Lin Shen
Publikováno v:
Aging (Albany NY)
RhoA is a member of the RHO family GTPases and is associated with essential functions in gastric cancer. In this study, we identified a gastric cancer biomarker, termed the "regulation of RhoA activity panel" (RRAP). Patients with gastric cancer from