Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Baochang Lai"'
Autor:
Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108722- (2024)
Summary: Epigenetic regulation of heart development remains incompletely understood. Here we show that LSD1, a histone demethylase, plays a crucial role in regulating cardiomyocyte proliferation during heart development. Cardiomyocyte-specific deleti
Externí odkaz:
https://doaj.org/article/ed296fea56c44464b7407d08e4463311
Autor:
Jia Liu, Xiong Du, Qinyu Yao, Tingting Jiang, Qi Cui, Xinya Xie, Ziwei Zhao, Baochang Lai, Nanping Wang, Lei Xiao
Publikováno v:
Journal of Functional Foods, Vol 99, Iss , Pp 105306- (2022)
Smoking is an independent risk factor for the cardiovascular diseases. Nicotine, a major component of tobacco, is responsible for the impaired endothelial-dependent vasorelaxation in smokers. Procyanidin B2 (PCB2), a natural flavonoid, has been repor
Externí odkaz:
https://doaj.org/article/d43af47eb9a841e5afa90d78d1423fc2
Autor:
Qinyu Yao, Jia Liu, Qi Cui, Tingting Jiang, Xinya Xie, Xiong Du, Ziwei Zhao, Baochang Lai, Lei Xiao, Nanping Wang
Publikováno v:
Nutrients, Vol 14, Iss 18, p 3871 (2022)
Hyperlipidemia with high blood levels of free fatty acids (FFA) is the leading cause of non-alcoholic steatohepatitis. CCN1 is a secreted matricellular protein that drives various cellular functions, including proliferation, migration, and differenti
Externí odkaz:
https://doaj.org/article/6346f477bf244063b5f518dafa2315f5
Procyanidin B2 Attenuates Nicotine-Induced Hepatocyte Pyroptosis through a PPARγ-Dependent Mechanism
Autor:
Jia Liu, Qinyu Yao, Xinya Xie, Qi Cui, Tingting Jiang, Ziwei Zhao, Xiong Du, Baochang Lai, Lei Xiao, Nanping Wang
Publikováno v:
Nutrients, Vol 14, Iss 9, p 1756 (2022)
Procyanidin B2 (PCB2), a natural flavonoid, has been demonstrated to exert anti-oxidation and anti-inflammatory effects on hepatic diseases. Increasing evidence shows the hepatoxicity of nicotine. However, whether PCB2 protects against nicotine-induc
Externí odkaz:
https://doaj.org/article/5bb3a4364bc0480784d615e37591a47f
Stachydrine protects eNOS uncoupling and ameliorates endothelial dysfunction induced by homocysteine
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-10 (2018)
Abstract Background Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular diseases (CVDs). Stachydrine (STA) is an active component in Chinese motherwort Leonurus heterophyllus sweet, which has been widely used for gynecologica
Externí odkaz:
https://doaj.org/article/9df8d8883e5c42e4b258793799f56293
Autor:
Ying Tian, Chunmiao Yang, Qinyu Yao, Lei Qian, Jia Liu, Xinya Xie, Wen Ma, Xin Nie, Baochang Lai, Lei Xiao, Nanping Wang
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Procyanidins, a subclass of flavonoids found in commonly consumed foods, possess potential anti-inflammatory activity. Manipulation of M1/M2 macrophage homeostasis is an effective strategy for the treatment of metabolic inflammatory diseases. The obj
Externí odkaz:
https://doaj.org/article/f8c360b4abdb4c69983701d5438cd6ee
Publikováno v:
Aging. 14:5590-5610
Protein tyrosine phosphatase, non-receptor type 11 (PTPN11) is a multifunctional tyrosine phosphatase and has a significant part in many types of tumors. As of yet, neither the expression profile of PTPN11 nor its significance in pan-cancer diagnosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3194a8b875efbfb87f72e8f701ef3040
https://doi.org/10.18632/aging.204171
https://doi.org/10.18632/aging.204171
Autor:
Xinye Yao, Yanbo Xue, Qiang Ma, Yajun Bai, Pu Jia, Yiman Zhang, Baochang Lai, Shuting He, Qiong Ma, Junbo Zhang, Hongyan Tian, Qian Yin, Xiaohui Zheng, Xiaopu Zheng
Publikováno v:
European Journal of Pharmacology. 952:175805
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::618397daa324c8a18192944430f3b829
https://doi.org/10.1016/j.ejphar.2023.175805
https://doi.org/10.1016/j.ejphar.2023.175805
Autor:
Qinyu, Yao, Jia, Liu, Qi, Cui, Tingting, Jiang, Xinya, Xie, Xiong, Du, Ziwei, Zhao, Baochang, Lai, Lei, Xiao, Nanping, Wang
Publikováno v:
Nutrients. 14(18)
Hyperlipidemia with high blood levels of free fatty acids (FFA) is the leading cause of non-alcoholic steatohepatitis. CCN1 is a secreted matricellular protein that drives various cellular functions, including proliferation, migration, and differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56c366000a6b27bd801a8fd698506808
https://pubmed.ncbi.nlm.nih.gov/36145246
https://pubmed.ncbi.nlm.nih.gov/36145246
Autor:
Qinyu, Yao, Qi, Cui, Jia, Liu, Xinya, Xie, Tingting, Jiang, Haodong, Wang, Ziwei, Zhao, Wenfei, Zhao, Xiong, Du, Baochang, Lai, Lei, Xiao, Nanping, Wang
Publikováno v:
The Journal of biological chemistry. 299(1)
Hyperlipidemia characterized by high blood levels of free fatty acids (FFAs) is important for the progression of inflammatory cardiovascular diseases. Integrin β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::001022b05c34fa6f1da9ff427fe26ef0
https://pubmed.ncbi.nlm.nih.gov/36470423
https://pubmed.ncbi.nlm.nih.gov/36470423