Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Bao-chun Jiang"'
Autor:
Fei-Fei Xu, Ling-Chi Kong, De-Li Cao, Bi-Xiao Ding, Qiong Wu, Yuan-Cheng Ding, Hao Wu, Bao-Chun Jiang
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 122-137 (2022)
Trigeminal neuropathic pain (TNP) arises due to peripheral nerve injury, the mechanisms underlying which are little known. The altered gene expression profile in sensory ganglia is critical for neuropathic pain generation and maintenance. We, therefo
Externí odkaz:
https://doaj.org/article/f051e82132754d55b4c63f1e80d60689
Autor:
Yu Zou, Xue-Hui Bai, Ling-Chi Kong, Fei-Fei Xu, Ting-Yu Ding, Peng-Fei Zhang, Fu-Lu Dong, Yue-Juan Ling, Bao-Chun Jiang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Histone lysine crotonylation (KCR), a novel epigenetic modification, is important in regulating a broad spectrum of biological processes and various diseases. However, whether KCR is involved in neuropathic pain remains to be elucidated. We found KCR
Externí odkaz:
https://doaj.org/article/cbe42e32ee464b3ab887d44c5f824a79
Autor:
Longfei Ma, Yangyuxin Huang, Fengjiang Zhang, Dave Schwinn Gao, Na Sun, Jinxuan Ren, Suyun Xia, Jia Li, Xinyi Peng, Lina Yu, Bao-Chun Jiang, Min Yan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Nerve injury-induced gene expression change in the spinal cord is critical for neuropathic pain genesis. RNA N6-methyladenosine (m6A) modification represents an additional layer of gene regulation. We showed that spinal nerve ligation (SNL) upregulat
Externí odkaz:
https://doaj.org/article/f26008b260c5478084ee950279bd9e2b
Publikováno v:
Neurobiology of Disease, Vol 79, Iss , Pp 100-110 (2015)
Chemotherapy drugs such as vincristine can produce painful peripheral neuropathy for which is still lack of effective treatment. Recent studies have demonstrated that neuroinflammation plays an important role in the pathogenesis of neuropathic pain.
Externí odkaz:
https://doaj.org/article/b7d849b73bc640158b41618ddf15789a
Publikováno v:
Bio-Protocol, Vol 7, Iss 1 (2017)
Primary afferents of sensory neurons mainly terminate in the spinal cord dorsal horn, which has an important role in the integration and modulation of sensory-related signals. Primary culture of mouse spinal dorsal horn neuron (SDHN) is useful for st
Externí odkaz:
https://doaj.org/article/d0cdcbab541b4b26951c5b1569fd3579
Autor:
De-bing YU, Min-li YU, Fei LIN, Bao-chun JIANG, Li-na YANG, Si-yu WANG, Ying ZHAO, Zheng-chao WNAG
Publikováno v:
Journal of Integrative Agriculture, Vol 13, Iss 5, Pp 1058-1064 (2014)
Recent reports have demonstrated that follicular atresia is initiated or caused by granulosa cell apoptosis followed by theca cell degeneration in mammalian ovaries, but the mechanism of follicular atresia is still to be elucidated. Therefore, our pr
Externí odkaz:
https://doaj.org/article/96628f6d67714b16a02c5cb9554169da
Autor:
De-bing YU, Bao-chun JIANG, Jing GONG, Fu-lu DONG, Ying-lin LU, Hui-jie YUE, Zheng-chao WANG, Wen-xing DU, An-yuan GUO
Publikováno v:
Journal of Integrative Agriculture, Vol 12, Iss 1, Pp 136-146 (2013)
MicroRNAs (miRNAs), which post-transcriptionally regulate gene expression by binding to the 3′ untranslated region of mRNAs to either inhibit or enhance translation, are involved in diverse biological processes. The use of high-throughput Solexa se
Externí odkaz:
https://doaj.org/article/8d9e1cd6a3f5430db1c4dbabbbfcfc50
Autor:
Haojia Li, Hongguang Bao, Jiayue Du, Yanan Shen, Yanna Si, Yuan Zhang, Tao Shan, Bao-Chun Jiang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-16 (2021)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Cognitive deficits are common in patients with sepsis. Previous studies in sepsis-associated encephalopathy (SAE) implicated the C-X-C chemokine receptor type (CXCR) 5. The present study used a mouse model of SAE to examine whether CXCR5 d
Autor:
Bao‐Chun Jiang, Ting‐Yu Ding, Chang‐Yun Guo, Xue‐Hui Bai, De‐Li Cao, Xiao‐Bo Wu, Wei‐Lin Sha, Ming Jiang, Long‐Jun Wu, Yong‐Jing Gao
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(27)
Peripheral nerve injury-induced spinal microglial proliferation plays a pivotal role in neuropathic pain. So far, key intracellular druggable molecules involved in this process are not identified. The nuclear factor of activated T-cells (NFAT1) is a
Publikováno v:
Journal of Pain Research. 13:3195-3206
Background Currently, medical treatment of inflammatory pain is limited by a lack of safe and effective therapies. Triptonide (TPN), a major component of Tripterygium wilfordii Hook.f. with low toxicity, has been shown to have good anti-inflammatory