Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Bao-Zhong Wang"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Enhancing influenza vaccine cross-protection is imperative to alleviate the significant public health burden of influenza. Heterologous sequential immunization may synergize diverse vaccine formulations and routes to improve vaccine potency
Externí odkaz:
https://doaj.org/article/2efe9602ec3047b2939e8ead92772ce7
Autor:
Chunhong Dong, Bao-Zhong Wang
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105172- (2024)
Externí odkaz:
https://doaj.org/article/0013b0c6c81540c9a275b607242f967d
Publikováno v:
Viruses, Vol 16, Iss 1, p 120 (2024)
mRNA-based vaccine technology has been significantly developed and enhanced, particularly highlighted by the authorization of mRNA vaccines for addressing the COVID-19 pandemic. Various biomaterials are developed in nano-scales and applied as mRNA va
Externí odkaz:
https://doaj.org/article/40e591f61755413486da13e4db5986a6
Autor:
Wandi Zhu, Lai Wei, Chunhong Dong, Ye Wang, Joo Kim, Yao Ma, Gilbert X. Gonzalez, Bao-Zhong Wang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 421-437 (2022)
Increasing preclinical and clinical results have demonstrated that mRNA vaccines efficiently prevent infectious diseases and are safe in animal models and humans. In this study, we fabricated a multivalent influenza mRNA lipid nanoparticle (LNP) vacc
Externí odkaz:
https://doaj.org/article/13e2101a7c6940d088ca27f0046f8e01
Autor:
Jeeva Subbbiah, Judy Oh, Ki-Hye Kim, Chong Hyun Shin, Bo Ryoung Park, Noopur Bhatnagar, Yu-Jin Jung, Youri Lee, Bao-Zhong Wang, Baik-Lin Seong, Sang-Moo Kang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 38-51 (2022)
Hemagglutinin (HA) stem-based vaccines have limitations in providing broad and effective protection against cross-group influenza viruses, despite being a promising universal vaccine target. To overcome the limited cross-protection and low efficacy b
Externí odkaz:
https://doaj.org/article/42facb3c8ddd484f95cf6fb57fc832aa
Autor:
Jeeva Subbiah, Judy Oh, Ki-Hye Kim, Chong-Hyun Shin, Bo Ryoung Park, Noopur Bhatnagar, Baik-Lin Seong, Bao-Zhong Wang, Sang-Moo Kang
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-15 (2022)
Abstract We developed a new chimeric M2e and H3 hemagglutinin (HA) stalk protein vaccine (M2e-H3 stalk) by genetic engineering of modified H3 stalk domain conjugated with conserved M2e epitopes to overcome the drawbacks of low efficacy by monomeric d
Externí odkaz:
https://doaj.org/article/211fd908db21495fb4fa0e4bc3f9c49e
Autor:
Shuang-Guo Zhu, Zheng-Guo Cheng, Hai-Hong Yin, Rui Zhou, Yu-Miao Yang, Jing Wang, Hao Zhu, Wei Wang, Bao-Zhong Wang, Wen-Bo Li, Hong-Yan Tao, You-Cai Xiong
Publikováno v:
BMC Plant Biology, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background The tradeoff between negative and positive interactions of facilitated species and facilitators may depend on the degree of resource availability in agroecosystems. However, the rhizospheric mechanisms driving trade-offs that occu
Externí odkaz:
https://doaj.org/article/64193a7263e44161aa0f1935a69e130e
Autor:
Wei Wang, Meng-Ying Li, Rui Zhou, Fei Mo, Bao-Zhong Wang, Li Zhu, Hong-Yan Tao, Ying Zhu, Wen-Li Wang, Ze-Ying Zhao, You-Cai Xiong
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105773- (2023)
Summary: We investigated a nature-based solution (NbS) via incorporating biocrust into alfalfa-maize intercropping system to test carbon sequestration in seriously eroded agricultural soils. Field investigation showed that the NbS (moss-dominated bio
Externí odkaz:
https://doaj.org/article/b826bd75e6414261accce261c4df698f
Autor:
Noopur Bhatnagar, Ki-Hye Kim, Jeeva Subbiah, Sakinah Muhammad-Worsham, Bo Ryoung Park, Rong Liu, Phillip Grovenstein, Bao-Zhong Wang, Sang-Moo Kang
Publikováno v:
Vaccines, Vol 11, Iss 7, p 1209 (2023)
With concerns about the efficacy of repeat annual influenza vaccination, it is important to better understand the impact of priming vaccine immunity and develop an effective vaccination strategy. Here, we determined the impact of heterologous prime-b
Externí odkaz:
https://doaj.org/article/31e1c05891a348caac930c57c05ae5d9
Autor:
Ki-Hye Kim, Zhuo Li, Noopur Bhatnagar, Jeeva Subbiah, Bo Ryoung Park, Chong Hyun Shin, Peter Pushko, Bao-Zhong Wang, Sang-Moo Kang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010755 (2022)
Annual influenza vaccination is recommended to update the variable hemagglutinin antigens. Here, we first designed a virus-like particle (VLP) displaying consensus multi-neuraminidase (NA) subtypes (cN1, cN2, B cNA) and M2 ectodomain (M2e) tandem rep
Externí odkaz:
https://doaj.org/article/5cbcb50a5b714910805518f33b6eb762