Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bao-Shi Wang"'
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The lack of biomarkers greatly limits the diagnosis and treatment of major depressive disorder (MDD). Endogenous L-carnitine (LC) and its derivative acetyl-L-carnitine (ALC) play antidepressant roles by improving brain energy metabolism, regulating n
Externí odkaz:
https://doaj.org/article/c3f7e4379c84474691504281b8b1fc91
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1121-1130 (2019)
Four series of total 35 new pyrazolo[4,3-d]pyrimidine compounds were designed, synthesized and evaluated for their inhibitory activity against LPS-induced NO production in RAW264.7 macrophages. Among them, compound 4e was found to be the most potent
Externí odkaz:
https://doaj.org/article/45c9708374ce451b9e875c9665bee3a8
Autor:
Jun Liang, Yaru Liu, Xinhua Liu, Quan Xia, Qingrong Xia, Chenchen Yang, Bao-Shi Wang, Jiequan Wang
Publikováno v:
International journal of biological macromolecules. 163
Telomeres, protective DNA-protein complexes at the end of eukaryotic linear chromosomes, play pivotal roles in the maintenance of genomic stability during cell division. When telomeres are severely shortened, cells stop dividing and die, consequently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595f5cebff01692d15db153bd2b12705
https://pubmed.ncbi.nlm.nih.gov/32673712
https://pubmed.ncbi.nlm.nih.gov/32673712
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 44:75-88
In this study, we constructed an l-methionine-producing recombinant strain from wild-type Escherichia coli W3110 by metabolic engineering. To enhance the carbon flux to methionine and derepression met regulon, thrBC, lysA, and metJ were deleted in tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f4f1af7cddde6a9e87ef98b62e679a
https://doi.org/10.1007/s10295-016-1870-3
https://doi.org/10.1007/s10295-016-1870-3
Autor:
Ming Ming Liu, Xin Huang, Xin Hua Liu, Liu Zeng Chen, Ming Ming Jiao, Wen Jian Tang, Bao Shi Wang, Jing Bo Shi
Publikováno v:
Journal of medicinal chemistry. 62(8)
In order to discover novel anti-inflammatory agents for treatment of arthritis and based on preliminary structure–activity relationships, four series (A–D) of total 90 new pyrazolo[4,3-d]pyrimidine compounds were designed and synthesized. All the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466ccab20aeb7f60af3a5f29e6787a3b
https://pubmed.ncbi.nlm.nih.gov/30925056
https://pubmed.ncbi.nlm.nih.gov/30925056
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1121-1130 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Four series of total 35 new pyrazolo[4,3-d]pyrimidine compounds were designed, synthesized and evaluated for their inhibitory activity against LPS-induced NO production in RAW264.7 macrophages. Among them, compound 4e was found to be the most potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b2d936e02dc97080fdd38d34948ab3
Publikováno v:
Advanced Materials Research. :1267-1271
In recent years, the phenomenon of vehicle overload in highway transportation is more and more serious. The three-dimensional dynamic FEM was adopted and a three-dimensional simulative model for asphalt pavement with subgrade based on cross-anisotrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f64950dfe82a81859d1ca256874115c0
https://doi.org/10.4028/www.scientific.net/amr.671-674.1267
https://doi.org/10.4028/www.scientific.net/amr.671-674.1267
Publikováno v:
Applied Mechanics and Materials. 307:308-311
Punch forming is widely used in many fields such as car industry, aviation, and mechanical industry. Along with the new requirement such as velocity, efficiency, costing of punch forming, there is more and more failure appearance. For example, fractu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce30252f2db7dc214b0ef61233ef1a92
https://doi.org/10.4028/www.scientific.net/amm.307.308
https://doi.org/10.4028/www.scientific.net/amm.307.308