Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Bao-Qing Gao"'
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Precise calling of promiscuous adenosine-to-inosine RNA editing sites from transcriptomic datasets is hindered by DNA mutations and sequencing/mapping errors. Here, we present a stepwise computational framework, called DEMINING, to distingui
Externí odkaz:
https://doaj.org/article/f250557117004a70885cf075c934198f
Autor:
Wenwen Zhao, Jifang Li, Xiao Wang, Wei Xu, Bao‐Qing Gao, Jiangchao Xiang, Yaofeng Hou, Wei Liu, Jing Wu, Qilian Qi, Jia Wei, Xiaoyu Yang, Lu Lu, Li Yang, Jia Chen, Bei Yang
Publikováno v:
MedComm, Vol 4, Iss 5, Pp n/a-n/a (2023)
Abstract The spike protein of SARS‐CoV‐2 hijacks the host angiotensin converting enzyme 2 (ACE2) to meditate its entry and is the primary target for vaccine development. Nevertheless, SARS‐CoV‐2 keeps evolving and the latest Omicron subvarian
Externí odkaz:
https://doaj.org/article/3f1cdc1af3d747359d28a9e3408e69b3
Autor:
Youkui Huang, Bao-Qing Gao, Quan Meng, Liang-Zhong Yang, Xu-Kai Ma, Hao Wu, Yu-Hang Pan, Li Yang, Dong Li, Ling-Ling Chen
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-35 (2023)
Abstract Background Understanding gene transcription and mRNA-protein (mRNP) dynamics in single cells in a multicellular organism has been challenging. The catalytically dead CRISPR-Cas13 (dCas13) system has been used to visualize RNAs in live cells
Externí odkaz:
https://doaj.org/article/9d3d709cfeea4ef89cf67df80011130b
Autor:
Xiaosa Li, Lina Zhou, Bao-Qing Gao, Guangye Li, Xiao Wang, Ying Wang, Jia Wei, Wenyan Han, Zixian Wang, Jifang Li, Runze Gao, Junjie Zhu, Wenchao Xu, Jing Wu, Bei Yang, Xiaodong Sun, Li Yang, Jia Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Prime editors can mediate all twelve types of base substitutions and small insertions or deletions in living cells but its efficiency remains low. Here the authors introduce same-sense mutations into pegRNAs to increase base-editing efficiency and th
Externí odkaz:
https://doaj.org/article/63feadad23c44c5db5815b59a02b9ad1
Publikováno v:
Cell Insight, Vol 1, Iss 4, Pp 100044- (2022)
Visualizing RNA dynamics is important for understanding RNA function. Catalytically dead (d) CRISPR-Cas13 systems have been established to image and track RNAs in living cells, but efficient dCas13 for RNA imaging is still limited. Here, we analyzed
Externí odkaz:
https://doaj.org/article/d9e8406defa640bb834ade3d22577e70