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Akademický článek

Central nervous system progression in advanced non–small cell lung cancer patients with EGFR mutations in response to first-line treatment with two EGFR-TKIs, gefitinib and erlotinib: a comparative study

Autor: Meng-Xia Li, Hao He, Zhi-Hua Ruan, Yu-Xi Zhu, Rong-Qing Li, Xiao He, Bao-Hua Lan, Zhi-Min Zhang, Guo-Dong Liu, Hua-Liang Xiao, Yan Wu, Bo Zhu, Ge Wang, Zhen-Zhou Yang

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)

Abstract Background Central nervous system (CNS) brain metastasis of advanced non-small cell lung cancer (NSCLC) patients confers a worse quality of life and prognosis. The efficacy comparison of two first-generation epidermal growth factor receptor

Externí odkaz: https://doaj.org/article/0bc162c5ca1e4caa8aee00e10ad55199

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Genistein promotes ionizing radiation-induced cell death by reducing cytoplasmic Bcl-xL levels in non-small cell lung cancer

Autor: Xiaojuan Lian, Yan Wu, Guo-Dong Liu, Zhimin Zhang, Ge Wang, Bao-Hua Lan, Mengxia Li, Feng Jin, Zhenzhou Yang, Hao He, Cheng-Xiong Xu, Guiyin Sun

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)

Genistein (GEN) has been previously reported to enhance the radiosensitivity of cancer cells; however, the detailed mechanisms remain unclear. Here, we report that GEN treatment inhibits the cytoplasmic distribution of Bcl-xL and increases nuclear Bc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c024c4a40e48b1d15717ee566c0624
https://doi.org/10.1038/s41598-017-18755-3

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Autor: Ge Wang, Yu-Xi Zhu, Zhi-Hua Ruan, Zhimin Zhang, Xiao He, Guo-Dong Liu, Hua-Liang Xiao, Hao He, Bo Zhu, Zhenzhou Yang, Mengxia Li, Rong-Qing Li, Bao-Hua Lan, Yan Wu

Publikováno v: BMC Cancer
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)

Background Central nervous system (CNS) brain metastasis of advanced non-small cell lung cancer (NSCLC) patients confers a worse quality of life and prognosis. The efficacy comparison of two first-generation epidermal growth factor receptor (EGFR) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c168f62dd8ea05b1b907ec9b088aa4d
http://europepmc.org/articles/PMC5379522

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