Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bao-Guo Huang"'
Autor:
John J. Shay, Hyacinthe Yarabe, Duane E. Rudisill, Bao-Guo Huang, Clive Pemberton, Matthew R. Powers, Hanna Reda G, Ann Marie Gelormini, Juan A Gamboa, James H. Peers, Kubiak Gregory G
Publikováno v:
Organic Process Research & Development. 15:1040-1045
The development of a scalable process for 3-arylsulfanyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid amides (1), potent casein kinase I inhibitors, is described. The rapid identification of suitabl...
Publikováno v:
Carbohydrate Research. 311:165-169
The chemical synthesis of beta-D-Gal-(1-->3)-6-O-SO3Na-beta-D-GlcNAc-(1-->6)-alpha-D-Man-O-+ ++C6H4NO2 (1) and beta-D-Gal-(1-->3)-6-O-SO3Na-beta-D-GlcNAc-(1-->2)-alpha-D-Man-OMe (2) is reported using a key glycosyl donor, phenyl O-(2,3,4,6-tetra-O-ac
Autor:
Rakesh K. Jain, Andrea Koenig, Bao-Guo Huang, Robert D. Locke, L Matta Khushi, Ajit Varki, Conrad F. Piskorz, Hui-Ling Han
Publikováno v:
Glycobiology. 8:707-717
The selectins interact in important normal and pathological situations with certain sialylated, fucosylated glycoconjugate ligands containing sialyl Lewisx(Neu5Acalpha2-3Galbeta1-4(Fucalpha1-3)GlcN Ac). Much effort has gone into the synthesis of sial
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1157-1160
Stereoselective syntheses of 3-O-sulfo and 3-O-sialyl LewisX analogs 1 and 2 were accomplished. Compound 1 showed greater inhibitory activity than the natural ligand sialyl LewisX against P and L-selectin.
Publikováno v:
ChemInform. 25
Publikováno v:
ChemInform. 25
The preparation of acetyl alkyl disulfides 2, which are key intermediates for the synthesis of alkyl hydrodisulfides 1, from disulfides is described. Disulfides are oxidized to sulfinothioic acid S-esters (thiosulfinates) which thioalkylate thioaceti
Publikováno v:
ChemInform. 28
Autor:
Bao-Guo Huang, M. Bobek
Publikováno v:
ChemInform. 29
7-(6-amino-6-deoxy- β - d -glucofuranosyl)-5-cyanopyrrolo[2,3- d ]pyrimidine ( 22 ) and 7-(3-aminomethyl-3-deoxy- β - d -allofuranosyl)-5-cyanopyrrolo[2,3- d ]pyrimidine ( 28 ) were synthesized by sequentially coupling silylated 4-amino-6-bromo-5-c
Publikováno v:
ChemInform. 30
Publikováno v:
The Journal of Organic Chemistry. 59:3227-3229