Exercise Prevents Memory Impairment Induced by Arsenic Exposure in Mice: Implication of Hippocampal BDNF and CREB.

Autor: Bao-Fei Sun, Qing-Qing Wang, Zi-Jiang Yu, Yan Yu, Chao-Lun Xiao, Chao-Sheng Kang, Guo Ge, Yan Linghu, Jun-De Zhu, Yu-Mei Li, Qiang-Ming Li, Shi-Peng Luo, Dang Yang, Lin Li, Wen-Yan Zhang, Guang Tian

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0137810 (2015)

High concentrations of arsenic, which can be occasionally found in drinking water, have been recognized as a global health problem. Exposure to arsenic can disrupt spatial memory; however, the underlying mechanism remains unclear. In the present stud

Externí odkaz: https://doaj.org/article/9e46dd650fe04ccdb2d781c2c0af45df

MicroRNA-92a Targets SERTAD3 and Regulates the Growth, Invasion, and Migration of Prostate Cancer Cells via the P53 Pathway

Autor: Shuo Zhang, Zi-Jiang Yu, Bao-Fei Sun, Heng Luo, Gui-Zhong Hou, Jia Yu

Publikováno v: OncoTargets and Therapy. 13:5495-5514

Background The miR-17-92 cluster, consisting of six mature miRNAs including miR-17, miR-18a, miR-19a, miR-19b, miR-20a, and miR-92a, plays a key role in the tumorigenesis and development of various cancers. The dysregulation of the cluster correlates

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c90c2e59b633d69e6822ee425325541a
https://doi.org/10.2147/ott.s249168

Effects of Edaravone on Functional Recovery of a Rat Model with Spinal Cord Injury Through Induced Differentiation of Bone Marrow Mesenchymal Stem Cells into Neuron-Like Cells

Autor: Yu-Mei Li, Laibing Liu, Bao-Fei Sun, Chao-Lun Xiao, Lin Li, Zijiang Yu, Yan Yu, Shi-Peng Luo

Publikováno v: Cellular reprogramming. 23(1)

Edaravone can induce differentiation of bone marrow mesenchymal stem cells (BMSCs) into neuron-like cells and replace lost cells by transplanting neuron-like cells to repair spinal cord injury (SCI). In this study, BMSCs were derived from the bone ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93372efc1a7d4d60862a0857deda939e
https://pubmed.ncbi.nlm.nih.gov/33400610

Expression, regulation and mechanism of action of the miR-17-92 cluster in tumor cells (Review)

Autor: Xu-Hui Zhu, Zi-Jiang Yu, Xing-Hui Wang, Xiao-Dong Zhang, Heng Luo, Li-li Fang, Bao-Fei Sun

Publikováno v: International Journal of Molecular Medicine

MicroRNAs (miRNAs), a class of short, single-stranded non-coding RNAs, regulate and control gene expression in eukaryotes by degrading mRNA at the post-transcriptional level. Regulation by miRNAs involves a plethora of biological processes, such as c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4ab7bdeef5890eefed33fc5b1e1b8f
https://doi.org/10.3892/ijmm.2017.3164

Potent Inhibition of miR-34b on Migration and Invasion in Metastatic Prostate Cancer Cells by Regulating the TGF-β Pathway

Autor: Shuo Zhang, Hai-bo Yuan, Zi-Jiang Yu, Li-li Fang, Jing Chen, Heng Luo, Bao-Fei Sun, Li-rong Huang

Publikováno v: International Journal of Molecular Sciences; Volume 18; Issue 12; Pages: 2762
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 18, Iss 12, p 2762 (2017)

The importance of miRNAs in the progression of prostate cancer (PCa) has further been supported by the finding that miRNAs have been identified as potential oncogenes or tumor suppressors in PCa. Indeed, in eukaryotes, miRNAs have been found to regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26d5cdf3285215399aa3413a1414d6c
https://doi.org/10.3390/ijms18122762