Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Bao Shi Wang"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1121-1130 (2019)
Four series of total 35 new pyrazolo[4,3-d]pyrimidine compounds were designed, synthesized and evaluated for their inhibitory activity against LPS-induced NO production in RAW264.7 macrophages. Among them, compound 4e was found to be the most potent
Externí odkaz:
https://doaj.org/article/45c9708374ce451b9e875c9665bee3a8
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The lack of biomarkers greatly limits the diagnosis and treatment of major depressive disorder (MDD). Endogenous L-carnitine (LC) and its derivative acetyl-L-carnitine (ALC) play antidepressant roles by improving brain energy metabolism, regulating n
Externí odkaz:
https://doaj.org/article/c3f7e4379c84474691504281b8b1fc91
Autor:
Jun Liang, Yaru Liu, Xinhua Liu, Quan Xia, Qingrong Xia, Chenchen Yang, Bao-Shi Wang, Jiequan Wang
Publikováno v:
International journal of biological macromolecules. 163
Telomeres, protective DNA-protein complexes at the end of eukaryotic linear chromosomes, play pivotal roles in the maintenance of genomic stability during cell division. When telomeres are severely shortened, cells stop dividing and die, consequently
Publikováno v:
Journal of Industrial Microbiology and Biotechnology. 44:75-88
In this study, we constructed an l-methionine-producing recombinant strain from wild-type Escherichia coli W3110 by metabolic engineering. To enhance the carbon flux to methionine and derepression met regulon, thrBC, lysA, and metJ were deleted in tu
Autor:
Ming Ming Liu, Xin Huang, Xin Hua Liu, Liu Zeng Chen, Ming Ming Jiao, Wen Jian Tang, Bao Shi Wang, Jing Bo Shi
Publikováno v:
Journal of medicinal chemistry. 62(8)
In order to discover novel anti-inflammatory agents for treatment of arthritis and based on preliminary structure–activity relationships, four series (A–D) of total 90 new pyrazolo[4,3-d]pyrimidine compounds were designed and synthesized. All the
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1121-1130 (2019)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Four series of total 35 new pyrazolo[4,3-d]pyrimidine compounds were designed, synthesized and evaluated for their inhibitory activity against LPS-induced NO production in RAW264.7 macrophages. Among them, compound 4e was found to be the most potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b2d936e02dc97080fdd38d34948ab3
Publikováno v:
Advanced Materials Research. :1267-1271
In recent years, the phenomenon of vehicle overload in highway transportation is more and more serious. The three-dimensional dynamic FEM was adopted and a three-dimensional simulative model for asphalt pavement with subgrade based on cross-anisotrop