Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Bao Q. Vuong"'
Autor:
Ophélie A. Martin, Morgane Thomas, Marie Marquet, Charlotte Bruzeau, Armand Garot, Mylène Brousse, Sébastien Bender, Claire Carrion, Jee Eun Choi, Bao Q. Vuong, Patricia J. Gearhart, Robert W. Maul, Sandrine Le Noir, Eric Pinaud
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntoductionTwo scaffold/matrix attachment regions (5’- and 3’-MARsEµ) flank the intronic core enhancer (cEµ) within the immunoglobulin heavy chain locus (IgH). Besides their conservation in mice and humans, the physiological role of MARsEµ is
Externí odkaz:
https://doaj.org/article/1ce217207e1e471da5b5f04499b868f6
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
B cells play a significant role in the adaptive immune response by secreting immunoglobulins that can recognize and neutralize foreign antigens. They develop from hematopoietic stem cells, which also give rise to other types of blood cells, such as m
Externí odkaz:
https://doaj.org/article/5ec685babf1f46b2b66f1e75b1d160d2
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
B cells produce high-affinity immunoglobulins (Igs), or antibodies, to eliminate foreign pathogens. Mature, naïve B cells expressing an antigen-specific cell surface Ig, or B cell receptor (BCR), are directed toward either an extrafollicular (EF) or
Externí odkaz:
https://doaj.org/article/815460ea5a0f4de5adc1162fef54a890
Publikováno v:
J Immunol
Class-switch recombination (CSR) produces secondary Ig isotypes and requires activation-induced cytidine deaminase (AID)–dependent DNA deamination of intronic switch regions within the IgH (Igh) gene locus. Noncanonical repair of deaminated DNA by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce0fb413e84b381b8c35910d6ff1009
https://doi.org/10.4049/jimmunol.2200590
https://doi.org/10.4049/jimmunol.2200590
Autor:
Lucie Fallone, Guilhem Lalle, Manuela Pereira-Abrantes, Emily Sible, Marie-Cécile Michallet, Bao Q. Vuong, Uzma Ayesha Hasan
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8a6909f51840febe74d3d1f065ecce
https://pubmed.ncbi.nlm.nih.gov/36469848
https://pubmed.ncbi.nlm.nih.gov/36469848
Autor:
Ophélie Martin, Morgane Thomas, Marie Marquet, Armand Garot, Mylène Brousse, Sébastien Bender, Claire Carrion, Jee Eun Choi, Bao Q. Vuong, Patricia J. Gearhart, Robert W. Maul, Sandrine Le Noir, Eric Pinaud
Two scaffold/matrix attachment regions (5’- and 3’-MARsEμ) flank the intronic core enhancer (cEμ) within the immunoglobulin heavy chain locus (IgH). Besides their conservation in mice and humans, the physiological role ofMARsEμis still unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d86731fe2f482f125c044b4971157098
https://doi.org/10.1101/2022.08.15.503996
https://doi.org/10.1101/2022.08.15.503996
Class switch recombination (CSR) produces secondary immunoglobulin isotypes and requires AID-dependent DNA deamination of intronic switch (S) regions within the immunoglobulin heavy chain (Igh) gene locus. Non-canonical repair of deaminated DNA by mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b72986ce416743fc8056773d90463abb
https://doi.org/10.1101/2022.07.28.501875
https://doi.org/10.1101/2022.07.28.501875
Autor:
Shan Zha, Ryan M. Smolkin, Bao Q. Vuong, Laura Nicolas, Montserrat Cols, Jayanta Chaudhuri, Keith C. Fernandez, William T. Yewdell, Wei-Feng Yen
Publikováno v:
J Immunol
The DNA damage response protein ATM has long been known to influence class switch recombination in ex vivo–cultured B cells. However, an assessment of B cell–intrinsic requirement of ATM in humoral responses in vivo was confounded by the fact tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fe7eca026a8a1630f2b9c296e71c08
https://doi.org/10.4049/jimmunol.1801033
https://doi.org/10.4049/jimmunol.1801033
Autor:
Emily Sible, Mary Attaway, Giuseppe Fiorica, Jee Eun Choi, Tzippora Chwat-Edelstein, Lyric Haughton, Donna Bedasee, Bao Q. Vuong
Publikováno v:
The Journal of Immunology. 208:112.14-112.14
Class switch recombination (CSR) produces secondary immunoglobulin isotypes and requires AID-dependent DNA deamination of intronic switch (S) regions within the immunoglobulin heavy chain gene locus. Non-canonical repair of deaminated DNA by mismatch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5a1bbc10c65a32db8555ce1e155ff79
https://doi.org/10.4049/jimmunol.208.supp.112.14
https://doi.org/10.4049/jimmunol.208.supp.112.14
Publikováno v:
The Journal of Immunology. 208:112.08-112.08
During a humoral immune response, B cells produce alternative immunoglobulin isotypes (IgG, IgA, IgE) through class switch recombination (CSR). Initiation of CSR requires AID-mediated deamination of switch (S) regions in the immunoglobulin heavy chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c3c6d81229ea5c0a947225939ba3b5b
https://doi.org/10.4049/jimmunol.208.supp.112.08
https://doi.org/10.4049/jimmunol.208.supp.112.08