Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Bao Le-Vinh"'
Autor:
Nguyet-Minh Nguyen Le, Sarah Zsák, Bao Le-Vinh, Julian David Friedl, Gergely Kali, Patrick Knoll, Hartwig Wolfram Seitter, Alexandra Koschak, Andreas Bernkop-Schnürch
Publikováno v:
ACS Applied Materials & Interfaces. 14:44981-44991
This study aimed to develop phosphatase-responsive ζ potential converting nanocarriers utilizing polyphosphate-coated cell-penetrating peptide (CPP)-decorated nanoemulsions (NEs) as a novel gene delivery system to retinal cells.Poly-l-lysine (PLL) w
Autor:
Julian David Friedl, Christian Steinbring, Bao Le-Vinh, Andreas Bernkop-Schnürch, Richard Wibel
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 163:109-119
We aim to prepare a size-shifting nanocarrier for site-targeting mucosal drug delivery that can penetrate through mucus gel layer and remain close to the absorption membrane. As nanocarriers can be engineered to penetrate mucus but they can also back
Autor:
Andreas Bernkop-Schnürch, Bao Le-Vinh, Nguyet-Minh Nguyen Le, Christian Steinbring, Barbara Matuszczak, Aamir Jalil
Publikováno v:
Journal of Colloid and Interface Science. 587:279-289
Aim It was the aim of this study to develop a zeta potential changing drug delivery system by decorating lipid-based nanocarriers with a polycationic cell penetrating peptide (CPP) and subsequently masking these cationic substructures with polyphosph
Autor:
Doris E. Braun, Bao Le-Vinh, Julian David Friedl, Andreas Bernkop-Schnürch, Martina Tribus, Arne Matteo Jörgensen
Publikováno v:
Journal of Colloid and Interface Science. 584:684-697
Four solidification methods for self-emulsifying drug delivery systems (SEDDS) were compared to evaluate the impact of solidification on storage stability of an incorporated protein. Papain was loaded in SEDDS via hydrophobic ion pairing (HIP). Liqui
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Akademický článek
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Publikováno v:
Acta biomaterialia. 144
Hydrophobic ion pairing is a promising strategy to raise the lipophilic character of therapeutic peptides and proteins. In past studies, docusate, an all-purpose surfactant with a dialkyl sulfosuccinate structure, showed highest potential as hydropho
Autor:
Nguyet-Minh Nguyen Le, Bao Le-Vinh, Julian David Friedl, Aamir Jalil, Gergely Kali, Andreas Bernkop-Schnürch
Publikováno v:
Carbohydrate polymers. 282
To prepare new polycationic pullulan derivatives exhibiting highly mucoadhesive and sustained drug release properties.Hydroxy groups of pullulan were activated with mesyl chloride followed by conjugation with low-molecular weight polyamines. Pullulan
Autor:
Andreas Bernkop-Schnürch, Imran Nazir, Barbara Matuszczak, Nguyet-Minh Nguyen Le, Bao Le-Vinh
Publikováno v:
International Journal of Biological Macromolecules. 133:647-655
Mucus permeation, mucoadhesion and cell membrane interaction are properties that a drug carrier needs to deliver macromolecule compounds through the mucus barrier and inside epithelial cells effectively. Herein, we prepared micelles from phosphorylat
Autor:
Andreas Bernkop-Schnürch, Flavia Laffleur, Thi Nhu Quynh Phan, Sergey Zaichik, Bao Le-Vinh, Ruba Ismail
Publikováno v:
ACS biomaterials scienceengineering. 6(9)
The aim of this study was to evaluate the potential of n-octadecyl sulfate (SOS) as a counterion for hydrophobic ion pairing (HIP) with exenatide—a potent glucagon-like peptide-1 (GLP-1) analogue i...