Výsledky vyhledávání - "Bao K. Huynh"

In Vitro Tests for Aerosol Deposition. VI: Realistic Testing with Different Mouth–Throat Models and In Vitro—In Vivo Correlations for a Dry Powder Inhaler, Metered Dose Inhaler, and Soft Mist Inhaler

Autor: Anubhav Kaviratna, Michael Hindle, Xiangyin Wei, Renishkumar Delvadia, Dennis Sandell, Peter R. Byron, Bao K. Huynh

Publikováno v: Journal of Aerosol Medicine and Pulmonary Drug Delivery. 31:358-371

Background: In vitro-in vivo correlations (IVIVC) for lung deposition may be established by testing inhalers in vitro with realistic mouth-throat (MT) models and inhalation profiles (IP). This study was designed to compare the currently available MT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::53cbac1d64d9f6fe7c40dd52a897bdc4
https://doi.org/10.1089/jamp.2018.1454

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The Development and Validation of an In Vitro Airway Model to Assess Realistic Airway Deposition and Drug Permeation Behavior of Orally Inhaled Products Across Synthetic Membranes

Autor: Paul M. Young, Daniela Traini, Bao K. Huynh, Dale Farkas, P. Worth Longest, Michael Hindle

Publikováno v: Journal of aerosol medicine and pulmonary drug delivery. 31(2)

Current in vitro approaches to assess lung deposition, dissolution, and cellular transport behavior of orally inhaled products (OIPs) have relied on compendial impactors to collect drug particles that are likely to deposit in the airway; however, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8119d115f9bf043c0eb426cb1fcd9461
https://pubmed.ncbi.nlm.nih.gov/28880765

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