Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Bao‐ye Sun"'
Autor:
Zhu‐tao Wang, Ruo‐yu Guan, Wei Gan, Zhang‐fu Yang, Bao‐ye Sun, Jing‐fang Wu, Dai Zhang, Guo‐qiang Sun, Xu‐kang Gao, Jin‐long Huang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Yong Yi, Bo Hu, Shuang‐Jian Qiu
Publikováno v:
Cancer Medicine, Vol 13, Iss 23, Pp n/a-n/a (2024)
ABSTRACT Background and Aims The immune microenvironment (IME) plays a crucial role in the progression of hepatocellular carcinoma (HCC). In HCC, the IME is often compromised by hepatitis B virus (HBV) infection, chronic inflammation, and fibrosis. B
Externí odkaz:
https://doaj.org/article/29758f7b7ba446a18cd6235d48291ea7
Autor:
Bao-Ye Sun, Zhu-Tao Wang, Ke-Zhu Chen, Yang Song, Jing-Fang Wu, Dai Zhang, Guo-Qiang Sun, Jian Zhou, Jia Fan, Bo Hu, Yong Yi, Shuang-Jian Qiu
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Lymph node metastasis (LNM) facilitates distant tumor colonization and leads to the high mortality in patients with intrahepatic cholangiocarcinoma (ICC). However, it remains elusive how ICC cells subvert immune surveillance within the prima
Externí odkaz:
https://doaj.org/article/d15404389ca7490597ad2e74e888929d
Autor:
Pei-Yun Zhou, Cheng Zhou, Wei Gan, Zheng Tang, Bao-Ye Sun, Jin-Long Huang, Gao Liu, Wei-Ren Liu, Meng-Xin Tian, Xi-Fei Jiang, Han Wang, Chen-Yang Tao, Yuan Fang, Wei-Feng Qu, Run Huang, Gui-Qi Zhu, Cheng Huang, Xiu-Tao Fu, Zhen-Bin Ding, Qiang Gao, Jian Zhou, Ying-Hong Shi, Yong Yi, Jia Fan, Shuang-Jian Qiu
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Primary liver cancer (PLC) poses a leading threat to human health, and its treatment options are limited. Meanwhile, the investigation of homogeneity and heterogeneity among PLCs remains challenging. Here, using single-cell RNA sequencing, s
Externí odkaz:
https://doaj.org/article/7116ab23faf54dce9c04956d710085f8
Autor:
Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain. In this study, we aim to investigate the r
Externí odkaz:
https://doaj.org/article/a2269dc43b3847e68049b1b8e6e359b4
Autor:
Bao-Ye Sun, Pei-Yi Gu, Ruo-Yu Guan, Cheng Zhou, Jian-Wei Lu, Zhang-Fu Yang, Chao Pan, Pei-Yun Zhou, Ya-Ping Zhu, Jia-Rui Li, Zhu-Tao Wang, Shan-Shan Gao, Wei Gan, Yong Yi, Ye Luo, Shuang-Jian Qiu
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Preoperative prediction of microvascular invasion (MVI) is critical for treatment strategy making in patients with hepatocellular carcinoma (HCC). We aimed to develop a deep learning (DL) model based on preoperative dynamic contra
Externí odkaz:
https://doaj.org/article/ce22ab6ca8394d6da70330f907ccbe6d
Autor:
Yong Yi, Bao-Ye Sun, Jia-Lei Weng, Cheng Zhou, Chen-Hao Zhou, Ming-Hao Cai, Jing-Yun Zhang, Hong Gao, Jian Sun, Jian Zhou, Jia Fan, Ning Ren, Shuang-Jian Qiu
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
PurposeWe aimed to investigate the feasibility of lenvatinib plus anti-PD-1 therapy as a conversion therapy for initially unresectable hepatocellular carcinoma (HCC).MethodsPatients with initially unresectable HCC who received combined lenvatinib and
Externí odkaz:
https://doaj.org/article/72ff8f762ff5481cb862750cec2995d5
Autor:
Gao Liu, Jian Sun, Zhang-Fu Yang, Cheng Zhou, Pei-Yun Zhou, Ruo-Yu Guan, Bao-Ye Sun, Zhu-Tao Wang, Jian Zhou, Jia Fan, Shuang-Jian Qiu, Yong Yi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-19 (2021)
Abstract Cancer-associated fibroblasts (CAFs) are commonly acquired activated extracellular matrix (ECM)-producing myofibroblasts, a phenotypes with multiple roles in hepatic fibrogenesis and carcinogenesis via crosstalk with cohabitating stromal/can
Externí odkaz:
https://doaj.org/article/672cada69bfa4dc6aea47f0c86c60221
Autor:
Bao-Ye Sun, Cheng Zhou, Ruo-Yu Guan, Gao Liu, Zhang-Fu Yang, Zhu-Tao Wang, Wei Gan, Jian Zhou, Jia Fan, Yong Yi, Shuang-Jian Qiu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
PurposeTo dissect the tumor ecosystem following immune checkpoint blockades (ICBs) in intrahepatic cholangiocarcinoma (ICC) at a single-cell level.MethodsSingle-cell RNA sequencing (scRNA-seq) data of 10 ICC patients for the ICB clinical trial were e
Externí odkaz:
https://doaj.org/article/d23645731d5e411dbefe13360590565c
Autor:
Cheng Zhou, Zhang-Fu Yang, Bao-Ye Sun, Yong Yi, Zheng Wang, Jian Zhou, Jia Fan, Wei Gan, Ning Ren, Shuang-Jian Qiu
Publikováno v:
Journal of Hepatocellular Carcinoma. 10:697-712
Cheng Zhou,1,* Zhang-Fu Yang,1,* Bao-Ye Sun,1,* Yong Yi,1 Zheng Wang,1 Jian Zhou,1 Jia Fan,1 Wei Gan,1 Ning Ren,1,2 Shuang-Jian Qiu1 1Department of Liver Surgery and Transplantation & Key Laboratory of Carcinogenesis and Cancer Invasion (
Autor:
Shuang-Jian Qiu, Ruo-Yu Guan, Jian Sun, Cheng Zhou, Jia Fan, Bao-Ye Sun, Gao Liu, Jian Zhou, Zhu-Tao Wang, Pei-Yun Zhou, Zhang-Fu Yang, Yong Yi
Publikováno v:
Digestive and Liver Disease. 54:692-700
Background Brahma-related gene 1 (BRG1) is essential for embryogenesis and cellular metabolism. A deficiency of BRG1 in vivo decreases lipid droplets, but the molecular mechanism underlying its role in lipid metabolism associated with hepatocellular