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Autor:
Yufeng Zhao, He Sihao, Sixu Chen, Qin Hao, Lei Yang, Zong Zhaowen, Bao Quanwei, Jiazhi Yang, Daocheng Liu
Publikováno v:
BMC Musculoskeletal Disorders, Vol 21, Iss 1, Pp 1-13 (2020)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background Fractures in older men are not uncommon and need to be healed as soon as possible to avoid related complications. Anti-osteoporotic drugs targeting Wnt/β-catenin and PTH (parathyroid hormone) to promote fracture healing have become an imp
Autor:
Yufeng Zhao, Sixu Chen, Lei Yang, Jiazhi Yang, Daocheng Liu, He Sihao, Zong Zhaowen, Qin Hao, Bao Quanwei
Publikováno v:
Science progress. 104(2)
To investigate whether activating the Wnt/β-catenin signalling pathway differentially promotes fracture healing in aged and adult individuals. CatnbTM2Kem, Catnblox(ex3) and wild-type adult and aged mice were used in this study. The femur was electr
Autor:
Yufeng Zhao, Bao Quanwei, Sixu Chen, Lei Yang, Daocheng Liu, Jiazhi Yang, Zong Zhaowen, He Sihao, Qin Hao
Publikováno v:
Clinical and Experimental Pharmacology & Physiology
Summary Parathyroid hormone (PTH) and agents related to the manipulation of Wnt/β‐catenin signalling are two promising anabolic anti‐osteoporotic therapies that have been shown to promote the healing of bone fractures. Now, it is widely accepted
Autor:
Yufeng Zhao, Daocheng Liu, Bao Quanwei, Zong Zhaowen, Qin Hao, Lei Yang, Huayu Liu, He Sihao, Sixu Chen
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 12, Pp 1-14 (2018)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
Type 1 diabetes mellitus (T1DM) is a pathological condition associated with osteopenia. WNT/β-catenin signaling is implicated in this process. Trabecular and cortical bone respond differently to WNT/β-catenin signaling in healthy mice. We investiga
Publikováno v:
Military medicine. 185(9-10)
Introduction For combatants without systematic medical education experience (CSMEE), it is necessary to participate in first-aid on the battlefield, but currently there is no effective training curriculum for CSMEE in Chinese military. Materials and
Publikováno v:
Biochemical and biophysical research communications. 525(2)
Bone marrow adipose tissue (BMAT) has recently been found to induce osteoclastogenesis by secreting RANKL. Although Type 1 diabetes mellitus (T1DM) has been reported to be associated with increased BMAT and bone loss, little is known about the relati
Autor:
Zong Zhaowen, Yue Shen, Bao Quanwei, Qin Hao, Daocheng Liu, Jianquan Feng, Ang Li, Huayu Liu, Junfeng Li, Sixu Chen
Publikováno v:
Cell and Tissue Research. 374:263-273
In recent years, several studies have found that the disruption of type IA receptor of bone morphogenetic proteins (BMPR1A) could increase bone mass. However, whether disruption of BMPR1A could have an effect on bone quality and bone strength is curr
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Akademický článek
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