BmooMPα-I, a Metalloproteinase Isolated from Bothrops moojeni Venom, Reduces Blood Pressure, Reverses Left Ventricular Remodeling and Improves Cardiac Electrical Conduction in Rats with Renovascular Hypertension.

Autor: Estrada JEC; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.; Laboratory of Hemostasis and Venoms, Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, RJ, Brazil., Rodrigues KE; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil., Maciel A; Center of Study of Biomolecules Applied in Medicine (CEBio), Oswaldo Cruz Foundation (Fiocruz Rondônia), Federal University of Rondônia, Porto Velho 76812-245, RO, Brazil., Bannwart CM; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil., Dias WF; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil., Hamoy M; Laboratory of Pharmacology and Toxicology of Natural Products, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil., Zingali RB; Laboratory of Hemostasis and Venoms, Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, RJ, Brazil., Soares AM; Center of Study of Biomolecules Applied in Medicine (CEBio), Oswaldo Cruz Foundation (Fiocruz Rondônia), Federal University of Rondônia, Porto Velho 76812-245, RO, Brazil.; São Lucas University Center, Porto Velho 76805-846, RO, Brazil., Ribeiro CHMA; Laboratory of Hematology, Faculty of Pharmacy, Institute of Health Science, Federal University of Pará, Belém 66075-110, PA, Brazil., Gerlach RF; Department of Basic and Oral Biology, Faculty of Dentistry of Ribeirao Preto, University of São Paulo (FORP/USP), Ribeirao Preto 14040-904, SP, Brazil., Monteiro MC; Laboratory of Clinical Immunology and Oxidative Stress, Pharmacy Faculty, Institute of Health Science, Federal University of Pará, Belém 66075-110, PA, Brazil., Prado AF; Laboratory of Pharmacology and Toxicology of Cardiovascular System, Institute of Biological Sciences, Federal University of Pará, Belém 66075-110, PA, Brazil.

Publikováno v: Toxins [Toxins (Basel)] 2022 Nov 05; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 05.

Aqueous Coriandrum sativum L. extract promotes neuroprotection against motor changes and oxidative damage in rat progeny after maternal exposure to methylmercury.

Autor: Rodrigues KE; Neuroscience and Cellular Biology Post Graduation Program, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., de Oliveira FR; Neuroscience and Cellular Biology Post Graduation Program, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil; Bromatology and Quality Control Laboratory, Health and Biological Sciences Department, Federal University of Amapa (UNIFAP), Macapa, Ap, Brazil., Barbosa BRC; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., Paraense RSO; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., Bannwart CM; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., Pinheiro BG; Behavioral and Inflammatory Pharmacology Laboratory, Health Sciences Institute, Pharmacy College, Federal University of Para, Belem, PA, Brazil., Botelho AS; Chemical Analysis Laboratory, Museum Paraense Emílio Goeldi, Belem, PA, Brazil., Muto NA; Amazonian Bioactive Compounds Valorization Center, Federal University of Para, Belem, PA, Brazil., do Amarante CB; Chemical Analysis Laboratory, Museum Paraense Emílio Goeldi, Belem, PA, Brazil., Hamoy M; Natural Products' Toxicology and Pharmacology Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., Macchi BM; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., Maia CDSF; Behavioral and Inflammatory Pharmacology Laboratory, Health Sciences Institute, Pharmacy College, Federal University of Para, Belem, PA, Brazil., do Prado AF; Structural Biology Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil., do Nascimento JLM; Neuroscience and Cellular Biology Post Graduation Program, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil; Molecular and Cellular Neurochemistry Laboratory, Biological Sciences Institute, Federal University of Para, Belem, PA, Brazil; National Institute of Science and Technology in Neuroimmunomodulation (INCT-NIM), Rio de Janeiro, RJ, Brazil; Pharmaceutical Sciences Post Graduation Program, Health and Biological Sciences Department, Federal University of Amapa (UNIFAP), Macapa, Ap, Brazil. Electronic address: jlmn@ufpa.br.

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2019 Nov; Vol. 133, pp. 110755. Date of Electronic Publication: 2019 Aug 10.