Výsledky vyhledávání - "Bankole Osuntokun"

High- and Low-Dose Oral Delayed-Release Mesalamine in Children With Mild-to-Moderately Active Ulcerative Colitis

Autor: Sanja Kolaček, Preston M. Dunnmon, Harland S. Winter, Eduardo Ibarguen-Secchia, Bankole Osuntokun, Melvin B. Heyman, Manoj Shah, Maciej Kaczmarski, J Antonio Quiros, Bruce R. Yacyshyn, Jaroslaw Kierkus, Barbara Iwańczak, Piotr Krzeski

Publikováno v: Journal of Pediatric Gastroenterology and Nutrition

Objective: The aim of the study was to assess the safety and efficacy of high- and low-dose oral, delayed-release mesalamine in a randomized, double-blind, active control study of children with mild-to-moderately active ulcerative colitis. Methods: P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395d52da545dc78169d68aa4e80efe0f
https://doi.org/10.1097/mpg.0000000000000530

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A Randomized Controlled Trial of Growth Hormone in Active Pediatric Crohn Disease

Autor: Edgar T. Ballard, Erin Bonkowski, Ramona Bezold, Cade M. Nylund, David J Klein, Rebecca Carey, Lee A. Denson, Margaret H. Collins, Mi-Ok Kim, Tara Willson, M. Susan Moyer, Bankole Osuntokun, Dandan Li

Publikováno v: Journal of Pediatric Gastroenterology & Nutrition. 51:130-139

Growth hormone (GH) may reduce symptoms and improve growth in Crohn disease (CD). The effect on mucosal inflammation is not known. We hypothesized that GH would improve both clinical and mucosal disease activity and stimulate linear growth in pediatr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497ad57348ae30403acc18c53d272b61
https://doi.org/10.1097/mpg.0b013e3181c992d6

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Signal Transducer and Activator of Transcription 5b Promotes Mucosal Tolerance in Pediatric Crohn's Disease and Murine Colitis

Autor: Bankole Osuntokun, Stuart J. Frank, Xiaonan Han, Kimberly Loesch, Nancy M. Benight, Lee A. Denson

Publikováno v: The American Journal of Pathology. 169:1999-2013

Growth hormone (GH) regulates anabolic metabolism via activation of the STAT5b transcription factor and reduces mucosal inflammation in colitis. Peroxisome proliferator-activated receptor (PPAR) gamma suppresses mucosal inflammation and is regulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a50230db1ef599e0ee9ca3379ab442
https://doi.org/10.2353/ajpath.2006.060186

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Clinical trials in pediatrics: The drug delivery dimension☆

Autor: Bankole Osuntokun

Publikováno v: Advanced Drug Delivery Reviews. 58:90-105

The medical and drug delivery devices needs of children are quite different and unique when compared to that of adults. The practice of off label use and modification of adult devices for pediatric use is widespread. Attendant risk and adverse effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dfc347552325318386a7eb12c64921
https://doi.org/10.1016/j.addr.2005.12.004

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Tumour necrosis factor alpha blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis

Autor: Kimberly Loesch, Bankole Osuntokun, Nancy M. Benight, Lee A. Denson, Stuart J. Frank, Xiaonan Han

Publikováno v: Gut. 56(1)

Neutralisation of tumour necrosis factor alpha (TNFalpha) restores systemic growth hormone function in patients with Crohn's disease, and induces mucosal healing. Anabolic effects of growth hormone depend on activation of the STAT5 transcription fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c107872bab44edec7e5a5675658d4a8
https://pubmed.ncbi.nlm.nih.gov/16777921

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