A three-antigen Plasmodium falciparum DNA prime-Adenovirus boost malaria vaccine regimen is superior to a two-antigen regimen and protects against controlled human malaria infection in healthy malaria-naïve adults.

Autor: Sklar MJ; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Maiolatesi S; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Patterson N; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Sedegah M; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Limbach K; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Teneza-Mora N; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Chuang I; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Hollis-Perry KM; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Banania JG; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Guzman I; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Ganeshan H; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Reyes S; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Hollingdale MR; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Wong M; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Lindstrom A; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Reyes A; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Alcorta Y; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Garver L; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America., Bankard K; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Belmonte A; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Belmonte M; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Huang J; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Gowda K; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Inoue S; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Velasco R; Naval Medical Research Center, Silver Spring, Maryland, United States of America.; Henry M. Jackson Foundation, Bethesda, Maryland, United States of America., Bergmann-Leitner E; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America., Hutter J; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Lee T; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Adams N; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Chaudhury S; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America., Hunt D; Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America., Tamminga C; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Berrie E; University of Oxford, Oxford, United Kingdom., Bellamy D; University of Oxford, Oxford, United Kingdom., Bittaye M; University of Oxford, Oxford, United Kingdom., Ewer K; University of Oxford, Oxford, United Kingdom., Diggs C; United States Agency for International Development (USAID), Washington, DC, United States of America., Soisson LA; United States Agency for International Development (USAID), Washington, DC, United States of America., Lawrie A; University of Oxford, Oxford, United Kingdom., Hill A; University of Oxford, Oxford, United Kingdom., Richie TL; Naval Medical Research Center, Malaria Department, Silver Spring, Maryland, United States of America., Villasante E; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Epstein JE; Naval Medical Research Center, Silver Spring, Maryland, United States of America., Duplessis CA; Naval Medical Research Center, Silver Spring, Maryland, United States of America.

Publikováno v: PloS one [PLoS One] 2021 Sep 08; Vol. 16 (9), pp. e0256980. Date of Electronic Publication: 2021 Sep 08 (Print Publication: 2021).