Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Bangwei Ding"'
Autor:
Xiao Wang, Justin A. Newman, Aaron M. Whittaker, Heather C. Johnson, Teresa Andreani, Kevin M. Maloney, Niki R. Patel, Mark A. Huffman, Mark McLaughlin, Bangwei Ding
Publikováno v:
Chemistry – A European Journal. 26:14118-14123
A 5-step enantioselective synthesis of the potent anti-HIV nucleoside islatravir is reported. The highly efficient route was enabled by a novel enantioselective alkynylation of an α,β-unsaturated ketone, a unique ozonolysis-dealkylation cascade in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ad69882d0d18454dffc9164ce24b67
https://doi.org/10.1002/chem.202003091
https://doi.org/10.1002/chem.202003091
Autor:
Mark Weisel, Hongming Li, Teresa Andreani, Christopher C. Nawrat, Aaron M. Whittaker, David M. Tschaen, Mark A. Huffman, Ryan D. Cohen, Mark McLaughlin, Bangwei Ding
Publikováno v:
Organic letters. 22(6)
A stereoselective nine-step synthesis of the potent HIV nucleoside reverse transcriptase translocation inhibitor (NRTTI) islatravir (EfdA, MK-8591) from 2-deoxyribose is described. Key findings include a diastereodivergent addition of an acetylide nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e04dea89c93801ec7898043b5b4056f
https://pubmed.ncbi.nlm.nih.gov/32108487
https://pubmed.ncbi.nlm.nih.gov/32108487
Autor:
Aaron M. Whittaker, Teresa Andreani, Niki R. Patel, Mark A. Huffman, Bangwei Ding, Heather C. Johnson, Kevin M. Maloney, Justin A. Newman, Mark McLaughlin, Xiao Wang
Publikováno v:
Chemistry – A European Journal. 26:14023-14023
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53eae7bb26afbe2d059e0dd7bb5d5f70
https://doi.org/10.1002/chem.202003600
https://doi.org/10.1002/chem.202003600
Autor:
Satyanarayan Bhat, Bangwei Ding, Qunying Guan, Chunhong Li, P. Savage, U. Taotafa, Stephen M. Milner
Publikováno v:
Wound Repair and Regeneration. 13:A28-A48
Sepsis remains the single most important cause for multiple organ failure and death following burn injury for which no effective treatment is currently available. Burn injury is associated with immunosuppression which promotes sepsis. Studies from ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68bbac669cc7d53b632e08c988840cf8
https://doi.org/10.1111/j.1067-1927.2005.130216aq.x
https://doi.org/10.1111/j.1067-1927.2005.130216aq.x
Autor:
Yang Liu, Jaime Cardenas-Garcia, Paul B. Savage, Mingjin Fan, Richard Evanson, Ning Yin, Thomas W. Orsak, Gracija Turin, Bangwei Ding
Publikováno v:
Journal of the American Chemical Society. 126:13642-13648
A key factor in the potential clinical utility of membrane-active antibiotics is their cell selectivity (i.e., prokaryote over eukaryote). Cationic steroid antibiotics were developed to mimic the lipid A binding character of polymyxin B and are shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47690d5b475462569a0b3def9a511de5
https://doi.org/10.1021/ja046909p
https://doi.org/10.1021/ja046909p
Publikováno v:
FEMS Microbiology Letters. 217:1-7
Cationic steroid antibiotics have been developed that display broad-spectrum antibacterial activity. These compounds are comprised of steroids appended with amine groups arranged to yield facially amphiphilic morphology. Examples of these antibiotics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff3cebb48310d73734d744e797dca33
https://doi.org/10.1111/j.1574-6968.2002.tb11448.x
https://doi.org/10.1111/j.1574-6968.2002.tb11448.x
Publikováno v:
ChemInform. 30
A shift from the computational to the synthetic side has taken place in the quest for compounds containing planar-tetracoordinate silicon: The first tetraazasilaspiro[4.4]nonane with two alkylene bridges has been prepared [Eq. (1)]. According to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::001a34b07dcb0b2e440e82203d0bd690
https://doi.org/10.1002/chin.199924174
https://doi.org/10.1002/chin.199924174
Publikováno v:
Journal of chromatography. A. 992(1-2)
A solid-phase microextraction (SPME) and gas chromatography–mass spectrometry (GC–MS) sampling and analysis method was developed for bis(diisopropylaminoethyl)disulfide (a degradation product of the nerve agent VX) in soil. A 30-min sampling time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13889a7e2d5cd497b96510a1cae73e47
https://pubmed.ncbi.nlm.nih.gov/12735457
https://pubmed.ncbi.nlm.nih.gov/12735457
Publikováno v:
ChemInform. 34
The Bu(3)Sn radical-induced reaction of o-iodobenzylvinylsilanes and o-iodoallylsilanes leads to cyclic products in yields of 40-60%. These regioselective cyclizations occur with high preference for a 5-exo and a 7-endo mode with a 6-exo mode being a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b78105d7e22f1748fb9c69498e0967
https://doi.org/10.1002/chin.200317148
https://doi.org/10.1002/chin.200317148
Autor:
Wesley G. Bentrude, Bangwei Ding
Publikováno v:
Journal of the American Chemical Society. 125(11)
Trimethyl phosphite, (MeO)(3)P, is introduced as an efficient and selective trap in oxiranylcarbinyl radical (2) systems, formed from haloepoxides 8-13 under thermal AIBN/n-Bu(3)SnH conditions at about 80 degrees C. Initially, the transformations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23231b54c3db7c74a1bac35403335c3a
https://pubmed.ncbi.nlm.nih.gov/12630880
https://pubmed.ncbi.nlm.nih.gov/12630880