Molecular switch role of Akt in Polygonatum odoratum lectin-induced apoptosis and autophagy in human non-small cell lung cancer A549 cells.

Autor: Chunyang Li, Jie Chen, Bangmin Lu, Zheng Shi, Hailian Wang, Bin Zhang, Kailiang Zhao, Wei Qi, Jinku Bao, Yi Wang

Publikováno v: PLoS ONE, Vol 9, Iss 7, p e101526 (2014)

Polygonatum odoratum lectin (POL), isolated from traditional Chinese medicine herb (Mill.) Druce, has drawn rising attention due to its wide biological activities. In the present study, anti-tumor effects, including apoptosis- and autophagy-inducing

Externí odkaz: https://doaj.org/article/150b6feb78d742df9edf5190f491a930

Mangiferin Facilitates Islet Regeneration and β-Cell Proliferation through Upregulation of Cell Cycle and β-Cell Regeneration Regulators

Autor: Yi Wang, Chunyang Li, Jinku Bao, Na An, Jing-Jing Zhang, Bin Zhang, Yuande Liu, Hailian Wang, Liang-Kai Zhao, Zheng Shi, Bangmin Lu

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 15; Issue 5; Pages: 9016-9035
International Journal of Molecular Sciences, Vol 15, Iss 5, Pp 9016-9035 (2014)

Mangiferin, a xanthonoid found in plants including mangoes and iris unguicularis, was suggested in previous studies to have anti-hyperglycemic function, though the underlying mechanisms are largely unknown. This study was designed to determine the th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e315e1d7885e28252c753c13aaafae9d
https://doi.org/10.3390/ijms15059016

Conformational study reveals amino acid residues essential for hemagglutinating and anti-proliferative activities of Clematis montana lectin

Autor: Bangmin, Lu, Bin, Zhang, Wei, Qi, Yanan, Zhu, Yan, Zhao, Nan, Zhou, Rong, Sun, Jinku, Bao, Chuanfang, Wu

Publikováno v: Acta biochimica et biophysica Sinica. 46(11)

Clematis montana lectin (CML), a novel mannose-binding lectin purified from C. montana Buch.-Ham stem (Ranunculaceae), has been proved to have hemagglutinating activity in rabbit erythrocytes and apoptosis-inducing activity in tumor cells. However, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71572b306716e2f5da07e68889a32424
https://pubmed.ncbi.nlm.nih.gov/25239139

Identification of novel kinase inhibitors by targeting a kinase‐related apoptotic protein–protein interaction network in HeLa cells

Autor: Bowen Zhang, Na An, Zi-jie Wang, Nan Zhou, S. L. Yang, F. Wang, Jin-ku Bao, Bangmin Lu, Chuan-fang Wu, Chun-yang Li, Ziyan Shi

Objectives Protein kinases orchestrate activation of signalling cascades in response to extra- and intracellular stimuli for regulation of cell proliferation. They are directly involved in a variety of diseases, particularly cancers. Systems biology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1880c80ecd8c33253f17a9a1aeabf1
https://europepmc.org/articles/PMC6496802/

Yak introgression into Tibetan Yellow cattle: evidences from mitochondrial DNA D-loop sequence analysis and β-lactoglobulin genetic variants.

Autor: ZHENGXIN LIU, BANGMIN LU, YONGJIANG MAO, YUPING LI, SUYU JIN, YUCAI ZHENG

Publikováno v: Indian Journal of Animal Sciences; Sep2012, Vol. 82 Issue 9, p1012-1015, 4p