Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Bangfu, Zhu"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-15 (2024)
Abstract Tauopathies are characterised by the pathological accumulation of misfolded tau. The emerging view is that toxic tau species drive synaptic dysfunction and potentially tau propagation before measurable neurodegeneration is evident, but the u
Externí odkaz:
https://doaj.org/article/b84b2ce52d414462b8e67e2f70fbe8f0
Autor:
Bangfu Zhu, Tom Parsons, Christopher Foley, Yeng Shaw, Travis Dunckley, Christopher Hulme, James J. L. Hodge
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Alzheimer’s disease (AD) involves pathological processing of amyloid precursor protein (APP) into amyloid-β and microtubule associated protein Tau (MAPT) into hyperphosphorylated Tau tangles leading to neurodegeneration. Only 5% of AD cas
Externí odkaz:
https://doaj.org/article/423c5c327b354518a7f745c5c9e8f33b
Autor:
Luis Solabre Valois, Vanilla (Hua) Shi, Paul Bishop, Bangfu Zhu, Yasuko Nakamura, Kevin A. Wilkinson, Jeremy M. Henley
Publikováno v:
IBRO Neuroscience Reports, Vol 10, Iss , Pp 196-207 (2021)
Botulinum neurotoxins (BoNTs) are extremely potent naturally occurring poisons that act by silencing neurotransmission. Intriguingly, in addition to preventing presynaptic vesicle fusion, BoNT serotype A (BoNT/A) can also promote axonal regeneration
Externí odkaz:
https://doaj.org/article/88b4e1fe21294079ad01e8ad984e48da
Autor:
Edgar Buhl, Yoon A. Kim, Tom Parsons, Bangfu Zhu, Ismael Santa-Maria, Roger Lefort, James J.L. Hodge
Publikováno v:
Neurobiology of Disease, Vol 170, Iss , Pp 105752- (2022)
Alzheimer's disease (AD) is the most prevalent neurodegenerative disease placing a great burden on people living with it, carers and society. Yet, the underlying patho-mechanisms remain unknown and treatments limited. To better understand the molecul
Externí odkaz:
https://doaj.org/article/fd2be2bb18ac40dd95bf0d2f58dcc521
Autor:
Bangfu Zhu, Tom Parsons, Wenche Stensen, John S. Mjøen Svendsen, Anders Fugelli, James J. L. Hodge
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alzheimer’s disease (AD) is the most common neurodegenerative disease which is becoming increasingly prevalent due to ageing populations resulting in huge social, economic, and health costs to the community. Despite the pathological processing of g
Externí odkaz:
https://doaj.org/article/ef83e297b25c4058a94e4f8340a74a31
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Globally, neonicotinoids are the most used insecticides, despite their well-documented sub-lethal effects on beneficial insects. Neonicotinoids are nicotinic acetylcholine receptor agonists. Memory, circadian rhythmicity and sleep are essent
Externí odkaz:
https://doaj.org/article/cddb73eff2564c4b9fb52c8cbfc10153
Autor:
Elaine L. Ferguson, Sameza Naseer, Lydia C. Powell, Joseph Hardwicke, Fraser I. Young, Bangfu Zhu, Qian Liu, Bing Song, David W. Thomas
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 69-78 (2018)
An essential aspect of stem cell in vitro culture and in vivo therapy is achieving sustained levels of growth factors to support stem cell survival and expansion, while maintaining their multipotency and differentiation potential. This study investig
Externí odkaz:
https://doaj.org/article/d0ba3d37481549e3969e6314d7acd88f
Autor:
Silvia Beatriz Sanchez Marco, Edgar Buhl, Rose Firth, Bangfu Zhu, Mary Gainsborough, Ana Beleza‐Meireles, Sandra Moore, Richard Caswell, Karen Stals, Sian Ellard, Cameron Kennedy, James J. L. Hodge, Anirban Majumdar
Publikováno v:
Clinical Genetics. 102:494-502
Cerebral palsy (CP) causes neurological disability in early childhood. Hypoxic-ischaemic injury plays a major role in its aetiology, nevertheless, genetic and epigenetic factors may contribute to the clinical presentation. Mutations in ADD3 (encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e09c9abdbf9b1a05ea294eec0fbec4c
https://doi.org/10.1111/cge.14220
https://doi.org/10.1111/cge.14220
Autor:
Wenkai Jiang, Diya Wang, Amr Alraies, Qian Liu, Bangfu Zhu, Alastair J. Sloan, Longxing Ni, Bing Song
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Smooth muscle cell- (SMC-) based tissue engineering provides a promising therapeutic strategy for SMC-related disorders. It has been demonstrated that human dental pulp stem cells (DPSCs) possess the potential to differentiate into mature bladder SMC
Externí odkaz:
https://doaj.org/article/2faf80471e174b06b2fef05955cfa38f
Autor:
Suzana Ulian-Benitez, Simon Bishop, Istvan Foldi, Jill Wentzell, Chinenye Okenwa, Manuel G Forero, Bangfu Zhu, Marta Moreira, Mark Phizacklea, Graham McIlroy, Guiyi Li, Nicholas J Gay, Alicia Hidalgo
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006968 (2017)
Neurotrophism, structural plasticity, learning and long-term memory in mammals critically depend on neurotrophins binding Trk receptors to activate tyrosine kinase (TyrK) signaling, but Drosophila lacks full-length Trks, raising the question of how t
Externí odkaz:
https://doaj.org/article/4511e4687c7c44eb8c7566d4706489f1