Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Bang-Chi Chen"'
Publikováno v:
ARKIVOC, Vol 2010, Iss 6, Pp 47-52 (2009)
Externí odkaz:
https://doaj.org/article/c18db02803614639a9bea6801db70f8c
Autor:
Rulin Zhao, Bei Wang, Hong Wu, John Hynes Jr., Katerina Leftheris, Balu Balasubramanian, Joel C. Barrish, Bang-Chi Chen
Publikováno v:
ARKIVOC, Vol 2010, Iss 6, Pp 89-95 (2009)
Externí odkaz:
https://doaj.org/article/e40aa32667fe46bb9ff06964b30a6eda
Autor:
Bang-Chi Chen, Rulin Zhao, Bei Wang, Roberto Droghini, Jean Lajeunesse, Pierre Sirard, Masaki Endo, Balu Balasubramanian, Joel C. Barrish
Publikováno v:
ARKIVOC, Vol 2010, Iss 6, Pp 32-38 (2009)
Externí odkaz:
https://doaj.org/article/dc04e1d3755b439780d1f227813f7778
Autor:
Rulin Zhao, Bang-Chi Chen, Mark S. Bednarz, Bei Wang, Amanda P. Skoumbourdis, Joseph E. Sundeen, T. G. Murali Dhar, Edwin J. Iwanowicz, Balu Balasubramanian, Joel C. Barrish
Publikováno v:
ARKIVOC, Vol 2007, Iss 12, Pp 36-42 (2007)
Externí odkaz:
https://doaj.org/article/7f97fd4f318845b9a3aed9278b8d475c
Autor:
Yan Shi, Ying Wang, Wei Meng, Robert P. Brigance, Denis E. Ryono, Scott Bolton, Hao Zhang, Sean Chen, Rebecca Smirk, Shiwei Tao, Joseph A. Tino, Kristin N. Williams, Richard Sulsky, Laura Nielsen, Bruce Ellsworth, Michael K. Y. Wong, Jung-Hui Sun, Leslie W. Leith, Dawn Sun, Dauh-Rurng Wu, Anuradha Gupta, Richard Rampulla, Arvind Mathur, Bang-Chi Chen, Aiying Wang, Helen G. Fuentes-Catanio, Lori Kunselman, Michael Cap, Jacob Zalaznick, Xiaohui Ma, Heng Liu, Joseph R. Taylor, Rachel Zebo, Beverly Jones, Stephen Kalinowski, Joann Swartz, Ada Staal, Kevin O’Malley, Lisa Kopcho, Jodi K. Muckelbauer, Stanley R. Krystek, Steven A. Spronk, Jovita Marcinkeviciene, Gerry Everlof, Xue-Qing Chen, Carrie Xu, Yi-Xin Li, Robert A. Langish, Yanou Yang, Qi Wang, Kamelia Behnia, Aberra Fura, Evan B. Janovitz, Nicola Pannacciulli, Steven Griffen, Bradley A. Zinker, John Krupinski, Mark Kirby, Jean Whaley, Robert Zahler, Joel C. Barrish, Jeffrey A. Robl, Peter T. W. Cheng
Publikováno v:
Journal of Medicinal Chemistry. 65:4291-4317
Autor:
Alaric J. Dyckman, Bang-Chi Chen, Percy H. Carter, Zhiwei Guo, Amarjit Singh, John L. Gilmore, James E. Sheppeck, Animesh Goswami, Huiping Zhang, Xiaoping Hou, Arvind Mathur
Publikováno v:
Organic Process Research & Development. 21:200-207
This article presents a stereospecific scale-up synthesis of (S)-1-((S)-2-hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid (BMS-960), a potent and selective isoxazole-containin
Autor:
Bang-Chi Chen, Percy H. Carter, Alaric J. Dyckman, William J. Pitts, Juliang Zhu, Huiping Zhang, Arvind Mathur, Scott H. Watterson, Xiaoping Hou
Publikováno v:
Organic Process Research & Development. 20:989-995
This article reports an efficient scale-up synthesis of 1-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylic acid (BMS-520), a potent and selective isoxazole-containing S1P1 receptor agonist. This pro
Autor:
Yuh-Lin Yang, Min Hu, Shuang Liu, Brandon Miles, Bingidimi I. Mobele, Wenge Cui, Richard E. Olson, Rulin Zhao, Kassoum Nacro, Matthew Isherwood, Bei Wang, Paul C. Lobben, Rasidul Amin, Bang-Chi Chen
Publikováno v:
Organic Process Research & Development. 20:44-50
Herein, we describe the enabling synthesis of (+)-BMS-820836, a 4,7-disubstituted tetrahydroisoquinoline which was developed as a treatment for a range of neurological diseases, including depression and neurophatic pain. In order to advance the drug
Autor:
Hong Wu, Gary L. Schieven, Joel C. Barrish, Bei Wang, Bang Chi Chen, Sam T. Chao, Gerry Everlof, Jung Hui Sun, Chunjian Liu, John H. Dodd, Murray McKinnon, Kathleen M. Gillooly, Katerina Leftheris, John Hynes, Tracy L. Taylor, Vivekananda M. Vrudhula, T. G. Murali Dhar, Stephen T. Wrobleski, Hongjian Zhang, David J. Shuster, Shuqun Lin, Kim W. McIntyre, Rulin Zhao, Christoph Gesenberg, James Lin, Punit Marathe
Publikováno v:
Journal of Medicinal Chemistry. 58:7775-7784
In search for prodrugs to address the issue of pH-dependent solubility and exposure associated with 1 (BMS-582949), a previously disclosed phase II clinical p38α MAP kinase inhibitor, a structurally novel clinical prodrug, 2 (BMS-751324), featuring