Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bang Jian Gong"'
Autor:
Karl J. M. Hanf, Joseph W. Arndt, YuTing Liu, Bang Jian Gong, Mia Rushe, Richelle Sopko, Ramiro Massol, Benjamin Smith, Yan Gao, Isin Dalkilic-Liddle, Xinhua Lee, Shanell Mojta, Zhaohui Shao, Sha Mi, R. Blake Pepinsky
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
LINGO-1 is a membrane protein of the central nervous system (CNS) that suppresses myelination of axons. Preclinical studies have revealed that blockade of LINGO-1 function leads to CNS repair in demyelinating animal models. The anti-LINGO-1 antibody
Externí odkaz:
https://doaj.org/article/90b48837c1134c3892cafeda6316ee68
Autor:
Shanell Mojta, Xinhua Lee, Yan Gao, Bang Jian Gong, Isin Dalkilic-Liddle, Ramiro H. Massol, YuTing Liu, Sha Mi, Karl J. M. Hanf, Benjamin Smith, Joseph Arndt, Zhaohui Shao, Richelle Sopko, R. Blake Pepinsky, Mia Rushe
Publikováno v:
mAbs
LINGO-1 is a membrane protein of the central nervous system (CNS) that suppresses myelination of axons. Preclinical studies have revealed that blockade of LINGO-1 function leads to CNS repair in demyelinating animal models. The anti-LINGO-1 antibody
Autor:
Dingyi Wen, Jana Dolnikova, R. Blake Pepinsky, Malgorzata M. Vecchi, Yongsheng Xiao, Bang Jian Gong
Publikováno v:
Analytical Chemistry. 89:4021-4030
Meteorin and Cometin (Meteorin-like) are secreted proteins belonging to a newly discovered growth factor family. Both proteins play important roles in neural development and may have potential as therapeutic targets or agents. Meteorin and Cometin ar
Autor:
Andreas Lehmann, Thomas Cameron, Yan Gao, Bang-Jian Gong, Dingyi Wen, Thomas Walz, Joseph Amatucci, Pepinsky R Blake, Martin Bush, Nels E. Pederson, Yaping Sun, Janine Ferrant
Publikováno v:
Biochemistry. 56(33)
Growth differentiation factor 11 (GDF11), a member of the transforming growth factor β (TGF-β) family, plays diverse roles in mammalian development. It is synthesized as a large, inactive precursor protein containing a prodomain, pro-GDF11, and exi
Autor:
Carol Huang, Jing-Xia Hao, H. Moore Arnold, Teit E. Johansen, Jesper Roland Jørgensen, Xiao-Jun Xu, Zsuzsanna Wiesenfeld-Hallin, Bang Jian Gong, Gordon Munro, Pepinsky R Blake, Lars Wahlberg
Publikováno v:
Experimental neurology. 237(2)
Neuropathic pain is caused by a lesion or disease to the somatosensory nervous system and current treatment merely reduces symptoms. Here, we investigate the potential therapeutic effect of the neurotrophic factor Meteorin on multiple signs of neurop
Publikováno v:
Biophysical Journal. 66(6):2062-2065
Various thio-reactive bifunctional crosslinkers as well as 5,5'-dithiobis(2-nitrobenzoate)-mediated disulfide bond formation were used to crosslink troponin-C and troponin-I, the Ca(2+)-binding and inhibitory subunits of troponin, respectively. In al
Publikováno v:
The Journal of Biochemistry. 114:453-456
Calponin is a thin filament-associated protein that is implicated in the regulation and maintenance of smooth muscle contraction. Molecular cloning of chicken gizzard calponin indicated the presence of two isoforms, alpha and beta, the expression of
Autor:
Lee Walus, Yinghui Hu, R. Blake Pepinsky, Guanrong Huang, Zhaohui Shao, Xinhua Lee, Bang Jian Gong, Robert H. Miller, Sha Mi, Benxiu Ji, Weixing Yang, Kenneth J. Rhodes
Publikováno v:
Nature medicine. 17(7)
Survival and differentiation of oligodendrocytes are important for the myelination of central nervous system (CNS) axons during development and crucial for myelin repair in CNS demyelinating diseases such as multiple sclerosis. Here we show that deat
Autor:
Borjack-Sjodin Paula Ann, Laura Silvian, Anthony Rossomando, P. Jin, Bang Jian Gong, C. Pelletier, Dinah W. Y. Sah, Pepinsky R Blake, Mia Rushe, Paul Carmillo
Publikováno v:
Biochemistry. 45(22)
Artemin (ART) promotes the growth of developing peripheral neurons by signaling through a multicomponent receptor complex comprised of a transmembrane tyrosine kinase receptor (cRET) and a specific glycosylphosphatidylinositol-linked co-receptor (GFR
Autor:
Pepinsky, Blake, Bang-Jian Gong, Yan Gao, Lehmann, Andreas, Ferrant, Janine, Amatucci, Joseph, Yaping Sun, Bush, Martin, Walz, Thomas, Pederson, Nels, Cameron, Thomas, Dingyi Wen
Publikováno v:
Biochemistry; 8/22/2017, Vol. 56 Issue 33, p4405-4418, 14p