Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms

Autor: Ochala J, Gustafson AM, Llano-Diez M, Renaud G, Li M, Aare S, Qaisar R, Banduseela VC, Hedström Y, Tang X, Dworkin B, Ford GC, Nair KS, Perera S, Gautel M, Larsson L

Publikováno v: JOURNAL OF PHYSIOLOGY-LONDON
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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The muscle wasting and impaired muscle function in critically ill intensive care unit (ICU) patients delay recovery from the primary disease, and have debilitating consequences that can persist for years after hospital discharge. It is likely that, i

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http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=8716

Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism.

Autor: Rigby MJ; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Lawton AJ; Department of Biomolecular Chemistry and the Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA., Kaur G; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA., Banduseela VC; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Pharmacology, University of Michigan, Ann Arbor, MI, USA., Kamm WE; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA., Lakkaraju A; Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, WI, USA.; Department of Ophthalmology and Anatomy, University of California, San Francisco, CA, USA., Denu JM; Department of Biomolecular Chemistry and the Wisconsin Institute for Discovery, University of Wisconsin-Madison, Madison, WI, USA., Puglielli L; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Waisman Center, University of Wisconsin-Madison, Madison, WI, USA. lp1@medicine.wisc.edu.; Geriatric Research Education Clinical Center, Veterans Affairs Medical Center, Madison, WI, USA. lp1@medicine.wisc.edu.

Publikováno v: Communications biology [Commun Biol] 2021 Apr 12; Vol. 4 (1), pp. 454. Date of Electronic Publication: 2021 Apr 12.

Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor.

Autor: Eftekharzadeh B; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., Banduseela VC; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Chiesa G; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., Martínez-Cristóbal P; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., Rauch JN; University of California at San Francisco, Department of Pharmaceutical Chemistry, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA., Nath SR; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Schwarz DMC; University of California at San Francisco, Department of Pharmaceutical Chemistry, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA., Shao H; University of California at San Francisco, Department of Pharmaceutical Chemistry, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA., Marin-Argany M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., Di Sanza C; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., Giorgetti E; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Yu Z; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA., Pierattelli R; CERM and Department of Chemistry 'Ugo Schiff', University of Florence, Via Luigi Sacconi 6, 50019, Sesto Fiorentino, Florence, Italy., Felli IC; CERM and Department of Chemistry 'Ugo Schiff', University of Florence, Via Luigi Sacconi 6, 50019, Sesto Fiorentino, Florence, Italy., Brun-Heath I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain., García J; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain., Nebreda ÁR; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain.; ICREA, Passeig Lluís Companys 23, 08010, Barcelona, Spain., Gestwicki JE; University of California at San Francisco, Department of Pharmaceutical Chemistry, 675 Nelson Rising Lane, San Francisco, CA, 94158, USA. jason.gestwicki@ucsf.edu., Lieberman AP; Department of Pathology, University of Michigan, Ann Arbor, MI, 48109, USA. liebermn@umich.edu., Salvatella X; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, 08028, Barcelona, Spain. xavier.salvatella@irbbarcelona.org.; Joint BSC-IRB Research Programme in Computational Biology, Baldiri Reixac 10, 08028, Barcelona, Spain. xavier.salvatella@irbbarcelona.org.; ICREA, Passeig Lluís Companys 23, 08010, Barcelona, Spain. xavier.salvatella@irbbarcelona.org.

Publikováno v: Nature communications [Nat Commun] 2019 Aug 08; Vol. 10 (1), pp. 3562. Date of Electronic Publication: 2019 Aug 08.

Differential effects of delayed aging on phenotype and striatal pathology in a murine model of Huntington disease.

Autor: Tallaksen-Greene SJ; Departments of Neurology., Sadagurski M; Internal Medicine., Zeng L; Departments of Neurology., Mauch R; Departments of Neurology., Perkins M; Departments of Neurology., Banduseela VC; Pathology and Geriatrics Center, University of Michigan, Ann Arbor, Michigan 48109., Lieberman AP; Pathology and Geriatrics Center, University of Michigan, Ann Arbor, Michigan 48109., Miller RA; Pathology and Geriatrics Center, University of Michigan, Ann Arbor, Michigan 48109., Paulson HL; Departments of Neurology, Michigan Alzheimer Disease Center, Ann Arbor, Michigan 48105, and., Albin RL; Departments of Neurology, Michigan Alzheimer Disease Center, Ann Arbor, Michigan 48105, and Neurology Service and Geriatrics Research, Education, and Clinical Center, VAAAHS, Ann Arbor, Michigan 48105 ralbin@umich.edu.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2014 Nov 19; Vol. 34 (47), pp. 15658-68.

Gene expression and muscle fiber function in a porcine ICU model.

Autor: Banduseela VC; Department of Clinical Neurophysiology, Uppsala University Hospital, SE-751 85 Uppsala, Sweden., Ochala J, Chen YW, Göransson H, Norman H, Radell P, Eriksson LI, Hoffman EP, Larsson L

Publikováno v: Physiological genomics [Physiol Genomics] 2009 Nov 06; Vol. 39 (3), pp. 141-59. Date of Electronic Publication: 2009 Aug 25.