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pro vyhledávání: '"Banala Ashwini Kumar"'
Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents
Autor:
Adla Mallareddy, Pranjal Sarma, Banala Ashwini Kumar, Ahmed Kamal, P. Raju, A. Lavanya, Manika Pal-Bhadra, S.N.C.V.L. Pushpavalli, J. Vinay Gopal, M. Janaki Ramaiah, Paidakula Suresh
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:4589-4600
A series of new 4β-acrylamidopodophyllotoxin derivatives ( 13a – o ) were synthesized by coupling of substituted acrylic acids ( 10a – l and 11m – o ) to the 4β-aminopodophyllotoxin. The synthesized derivatives 13a – o were evaluated for th
Autor:
Paidakula Suresh, Adla Mallareddy, Nishant Jain, Papagari Venkat Reddy, Thokhir Basha Shaik, Jaki R. Tamboli, Ahmed Kamal, Banala Ashwini Kumar, Shasi V. Kalivendi, P. Raju
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2349-2358
A series of novel conjugates of 4-aza-2,3-didehydropodophyllotoxins ( 11a – w ) were synthesized by a straightforward one-step multicomponent synthesis that demonstrated cytotoxicity against five human cancer cell lines (breast, oral, colon, lung a