Zobrazeno 1 - 10
of 264
pro vyhledávání: '"Ban‐Hock Toh"'
Autor:
Kurt Brassington, Peter Kanellakis, Anh Cao, Ban-Hock Toh, Karlheinz Peter, Alex Bobik, Tin Kyaw
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Graphical AbstractCardiac fibrosis developed from fibrotic remodelling due to hypertension leads to heart failure. Immune cells are abundantly accumulated in fibrotic regions, but exact mechanisms how they contributed to cardiac fibrosis are not clea
Externí odkaz:
https://doaj.org/article/edd23d1ce87f4ca1a269d46a10cf595f
Autor:
Christopher Tay, Peter Kanellakis, Hamid Hosseini, Anh Cao, Ban-Hock Toh, Alex Bobik, Tin Kyaw
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Interaction between B and CD4 T cells is crucial for their optimal responses in adaptive immunity. Immune responses augmented by their partnership promote chronic inflammation. Here we report that interaction between B and CD4 T cells augments their
Externí odkaz:
https://doaj.org/article/4b82664215c64f1c8f01023c27847cad
Publikováno v:
Autoimmunity, Vol 50, Iss 1, Pp 52-56 (2017)
Atherosclerosis is initiated by cholesterol entry into arteries that triggers chronic immune-inflammatory lesions in the vessels. Early lesions are clinically insignificant but advanced complex lesions and vulnerable rupture prone lesions impact on q
Externí odkaz:
https://doaj.org/article/9f5e4eee642640c097d9da28647c344f
Autor:
Hamid Hosseini, Li Yi, Peter Kanellakis, Anh Cao, Christopher Tay, Karlheinz Peter, Alex Bobik, Ban‐Hock Toh, Tin Kyaw
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 13 (2018)
Background Peritoneal B1a cells attenuate atherosclerosis by secreting natural polyclonal immunoglobulin M (IgM). Regulatory B cells expressing T‐cell immunoglobulin mucin domain‐1 (TIM‐1) expanded through TIM‐1 ligation by anti‐TIM‐1 mon
Externí odkaz:
https://doaj.org/article/e30aedb2fc494a77b456e36737856c79
Autor:
Hamid Hosseini, Yi Li, Peter Kanellakis, Christopher Tay, Anh Cao, Edgar Liu, Karlheinz Peter, Peter Tipping, Ban‐Hock Toh, Alex Bobik, Tin Kyaw
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 11 (2016)
BackgroundWe previously identified peritoneal B1a cells that secrete natural IgM as a key atheroprotective B cell subset. However, the molecules that activate atheroprotective B1a cells are unknown. Here, we investigated whether Toll‐like receptors
Externí odkaz:
https://doaj.org/article/3d1b77b9100748849b08e0c5a5632051
Autor:
Tin Kyaw, Peng Cui, Christopher Tay, Peter Kanellakis, Hamid Hosseini, Edgar Liu, Antonius G Rolink, Peter Tipping, Alex Bobik, Ban-Hock Toh
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60430 (2013)
AIMS: Option to attenuate atherosclerosis by depleting B2 cells is currently limited to anti-CD20 antibodies which deplete all B-cell subtypes. In the present study we evaluated the capacity of a monoclonal antibody to B cell activating factor-recept
Externí odkaz:
https://doaj.org/article/24662418a8794762a7d1e6f34cf09439
Autor:
Tin Kyaw, Christopher Tay, Hamid Hosseini, Peter Kanellakis, Tahlia Gadowski, Fabeinne MacKay, Peter Tipping, Alex Bobik, Ban-Hock Toh
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29371 (2012)
We have recently identified conventional B2 cells as atherogenic and B1a cells as atheroprotective in hypercholesterolemic ApoE(-/-) mice. Here, we examined the development of atherosclerosis in BAFF-R deficient ApoE(-/-) mice because B2 cells but no
Externí odkaz:
https://doaj.org/article/da712721b2494c80a384d6a1169e4e95
Autor:
Yu Han Liu, Vijesh Vaghjiani, Jing Yang Tee, Kelly To, Peng Cui, Ding Yuan Oh, Ursula Manuelpillai, Ban-Hock Toh, James Chan
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35758 (2012)
Human amniotic epithelial cells (hAEC) have stem cell-like features and immunomodulatory properties. Here we show that hAEC significantly suppressed splenocyte proliferation in vitro and potently attenuated a mouse model of multiple sclerosis (MS). C
Externí odkaz:
https://doaj.org/article/6e3a963e955e4e66ab94f88a15e7d859
Autor:
Karlheinz Peter, Alex L. Huang, Axel Kallies, Paula Loveland, Alex Bobik, Anh Cao, Peter Kanellakis, Tin Kyaw, Ban-Hock Toh
Publikováno v:
European Heart Journal. 42:938-947
Aims Myocardial infarction (MI) accelerates atherosclerosis and greatly increases the risk of recurrent cardiovascular events for many years, in particular, strokes and MIs. Because B cell-derived autoantibodies produced in response to MI also persis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379f39c9a0ff50a5876a51cf803b95cf
https://doi.org/10.1093/eurheartj/ehaa995
https://doi.org/10.1093/eurheartj/ehaa995
Autor:
Brassington, Kurt, Kanellakis, Peter, Anh Cao, Ban-Hock Toh, Peter, Karlheinz, Bobik, Alex, Tin Kyaw
Publikováno v:
Frontiers in Immunology; 11/22/2022, Vol. 13, p01-19, 19p