Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Bambos M. Charalambous"'
Publikováno v:
Future Microbiology. 9:189-201
ABSTRACT: An estimated 498 million new cases of curable sexually transmitted infections occur worldwide annually. Of these, 106 million are gonococcal infections, rendering gonorrhea the second most prevalent bacterial sexually transmitted infection
Autor:
Bruno Pichon, Stephen H. Gillespie, Marcus H. Y. Leung, Kathrin Freystatter, Kevin Bryson, Bambos M. Charalambous, Giles Edwards
Publikováno v:
Journal of Clinical Microbiology. 50:2419-2427
The introduction of pneumococcal conjugate vaccines necessitates continued monitoring of circulating strains to assess vaccine efficacy and replacement serotypes. Conventional serological methods are costly, labor-intensive, and prone to misidentific
Publikováno v:
Reviews in Medical Microbiology. 23:45-51
Autor:
Darlington Mwenya, James Mwansa, Stephen H. Gillespie, Sarah Walker, Patrick P. J. Phillips, Sarah L. Batt, Andrew J. Nunn, Diana M. Gibb, Bambos M. Charalambous
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:3756-3762
This is a substudy of a larger randomized controlled trial on HIV-infected Zambian children, which revealed that cotrimoxazole prophylaxis reduced morbidity and mortality despite a background of high cotrimoxazole resistance. The impact of cotrimoxaz
Autor:
Bambos M. Charalambous
Publikováno v:
Reviews in Medical Microbiology. 18:73-78
Despite the availability of antibiotics Streptococcus pneumoniae (the pneumococcus) is still a leading cause of invasive disease, with over a million children dying world-wide, particularly from pneumonia. The rising tide of resistance is reducing an
Publikováno v:
Shock. 28:15-23
Proinflammatory cytokines are now thought to play a key role in the pathophysiology of chronic heart failure, driving both symptomatic presentation and disease progression. We propose that this proinflammatory state, in turn, may be sustained through
Publikováno v:
Scandinavian Journal of Immunology. 62:385-392
Life-threatening meningitis and septicaemia caused by Neisseria meningitidis are a public health priority, and their prevention by vaccination is a major objective. Meningococcal capsular polysaccharide-based vaccines are effective against the major
Autor:
Noel E. Sam, Sarah L. Batt, A. C. Peek, Stephen H. Gillespie, Bambos M. Charalambous, H. Mwerinde
Publikováno v:
Journal of Clinical Microbiology. 41:5551-5556
The need to design effective Streptococcus pneumoniae vaccines and to monitor resistance means that it is essential to have efficient methods to determine carriage rates. Two liquid media, consisting of skim milk, glycerol, glucose, and tryptone soya
Autor:
Anthony W. Solomon, Patrick Massae, Bambos M. Charalambous, Charles Knirsch, Noel E. Sam, Dean Everett, Stephen H. Gillespie, David Mabey, Sarah L. Batt, Salesia Safari
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:2765-2769
Community distribution of azithromycin has an important role to play in trachoma control. Previous studies have suggested that this may increase the prevalence of macrolide-resistant Streptococcus pneumoniae. S. pneumoniae was isolated from children
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 166:31-35
Studies of early bactericidal activity (EBA) are important in the rapid evaluation of new antituberculosis drugs. Historically, these have concentrated on the log fall in the viable count in sputum during the first 48 hours of therapy. In this paper,