Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Bamaprasad Dutta"'
Autor:
Shining Loo, Antony Kam, Bamaprasad Dutta, Xiaohong Zhang, Nan Feng, Siu Kwan Sze, Chuan-Fa Liu, Xiaoliang Wang, James P. Tam
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 653-666 (2024)
Stress and illness connection is complex and involves multiple physiological systems. Panax ginsengs, reputed for their broad-spectrum “cure-all” effect, are widely prescribed to treat stress and related illnesses. However, the identity of ginsen
Externí odkaz:
https://doaj.org/article/2d32b34c63674ff9b48d2c7783da2f7e
Publikováno v:
Cells, Vol 12, Iss 10, p 1401 (2023)
Hypoxia-induced vascular endothelial dysfunction (VED) is a significant contributor to several severe human diseases, including heart disease, stroke, dementia, and cancer. However, current treatment options for VED are limited due to the lack of und
Externí odkaz:
https://doaj.org/article/ba0a05736fd448119c5de55372e432fe
Autor:
Meng Shi, Bing Chen, Divyanshu Mahajan, Boon Kim Boh, Yan Zhou, Bamaprasad Dutta, Hieng Chiong Tie, Siu Kwan Sze, Geng Wu, Lei Lu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Amino acid levels are known to regulate anabolic and catabolic pathways. Here, the authors report that amino acids also affect membrane trafficking by stimulating endosome-to-Golgi retrograde trafficking and regulating cell surface localization of ce
Externí odkaz:
https://doaj.org/article/bdf4ba7aecf941509eabf74712806aed
Autor:
Bamaprasad Dutta, Jung Eun Park, Subodh Kumar, Piliang Hao, Xavier Gallart-Palau, Aida Serra, Yan Ren, Vitaly Sorokin, Chuen Neng Lee, Hee Hwa Ho, Dominique de Kleijn, Siu Kwan Sze
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Atherosclerosis arises from leukocyte infiltration and thickening of the artery walls and constitutes a major component of vascular disease pathology, but the molecular events underpinning this process are not fully understood. Proteins cont
Externí odkaz:
https://doaj.org/article/c8ed2a39083f4ac783ecce40423ac6b2
Autor:
Chee Fan Tan, Hui San Teo, Jung Eun Park, Bamaprasad Dutta, Shun Wilford Tse, Melvin Khee-Shing Leow, Walter Wahli, Siu Kwan Sze
Publikováno v:
Cells, Vol 9, Iss 5, p 1320 (2020)
Studies have shown that the process of extracellular vesicles (EVs) secretion and lysosome status are linked. When the lysosome is under stress, the cells would secrete more EVs to maintain cellular homeostasis. However, the process that governs lyso
Externí odkaz:
https://doaj.org/article/59c6442a021c414f9d523c7c43b639d5
Publikováno v:
Molecules, Vol 24, Iss 13, p 2417 (2019)
Grafting a bioactive peptide onto a disulfide-rich scaffold is a promising approach to improve its structure and metabolic stability. The ginkgo plant-derived β-ginkgotide β-gB1 is a highly unusual molecule: Small, hyperdisulfide, and found only in
Externí odkaz:
https://doaj.org/article/558df13d3e0c4ec2ae10f89f21dd41e8
Autor:
Alexandre Chojnowski, Peh Fern Ong, Esther SM Wong, John SY Lim, Rafidah A Mutalif, Raju Navasankari, Bamaprasad Dutta, Henry Yang, Yi Y Liow, Siu K Sze, Thomas Boudier, Graham D Wright, Alan Colman, Brian Burke, Colin L Stewart, Oliver Dreesen
Publikováno v:
eLife, Vol 4 (2015)
Hutchinson-Gilford progeria (HGPS) is a premature ageing syndrome caused by a mutation in LMNA, resulting in a truncated form of lamin A called progerin. Progerin triggers loss of the heterochromatic marker H3K27me3, and premature senescence, which i
Externí odkaz:
https://doaj.org/article/7048e43aee15493aa8dd8effd02435c3
Autor:
Shining Loo, Antony Kam, Bamaprasad Dutta, Xiaohong Zhang, Nan Feng, Siu Kwan Sze, Chuan-Fa Liu, Xiaoliang Wang, James P. Tam
Ginseng has been known as a “cure-all” traditional medicine to treat various illnesses and as an adaptogen to relieve stress. However, the known active compounds of ginseng are small-molecule metabolites. Here we report ginsentides, which are dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38875b74c1ba0e1d77f732ba7d34e52d
https://doi.org/10.1101/2023.04.05.535784
https://doi.org/10.1101/2023.04.05.535784
Autor:
Bamaprasad Dutta, Shun Wilford Tse, James P. Tam, Kheng Wei Yeoh, Jee Keem Low, Oi Lian Kon, Siu Kwan Sze, Jung Eun Park, Nikhil Gupta, Chee Fan Tan
Publikováno v:
Oncogene. 38:5158-5173
Developing tumors rapidly outgrow their oxygen supply and are subject to hypoxia, which stimulates hypersecretion of tumor-derived exosomes that promote angiogenesis, metastasis, and immunosuppression, but the molecular mediators of these pathologica
Autor:
Geng Wu, Lei Lu, Hieng Chiong Tie, Divyanshu Mahajan, Siu Kwan Sze, Bing Chen, Boon Kim Boh, Meng Shi, Yan Zhou, Bamaprasad Dutta
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
The endosome-to-Golgi or endocytic retrograde trafficking pathway is an important post-Golgi recycling route. Here we show that amino acids (AAs) can stimulate the retrograde trafficking and regulate the cell surface localization of certain Golgi mem