Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Baluapuri A"'
Autor:
Christoph Otto, Carolin Kastner, Stefanie Schmidt, Konstantin Uttinger, Apoorva Baluapuri, Sarah Denk, Mathias T. Rosenfeldt, Andreas Rosenwald, Florian Roehrig, Carsten P. Ade, Christina Schuelein‐Voelk, Markus E. Diefenbacher, Christoph‐Thomas Germer, Elmar Wolf, Martin Eilers, Armin Wiegering
Publikováno v:
Molecular Oncology, Vol 16, Iss 15, Pp 2788-2809 (2022)
Ribosomal biogenesis and protein synthesis are deregulated in most cancers, suggesting that interfering with translation machinery may hold significant therapeutic potential. Here, we show that loss of the tumor suppressor adenomatous polyposis coli
Externí odkaz:
https://doaj.org/article/86ca5923c6f34dcb85b7467dac7cbb83
Autor:
Thomas Fischer, Oliver Hartmann, Michaela Reissland, Cristian Prieto-Garcia, Kevin Klann, Nikolett Pahor, Christina Schülein-Völk, Apoorva Baluapuri, Bülent Polat, Arya Abazari, Elena Gerhard-Hartmann, Hans-Georg Kopp, Frank Essmann, Mathias Rosenfeldt, Christian Münch, Michael Flentje, Markus E. Diefenbacher
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-22 (2022)
Abstract Background Despite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN. These tumors are supposed t
Externí odkaz:
https://doaj.org/article/6e2b77747e884b2d9b01fa05018ce46e
Autor:
Markus Schick, Le Zhang, Sabine Maurer, Hans Carlo Maurer, Konstandina Isaakaidis, Lara Schneider, Upayan Patra, Kathrin Schunck, Elena Rohleder, Julia Hofstetter, Apoorva Baluapuri, Anna Katharina Scherger, Julia Slotta-Huspenina, Franziska Hettler, Julia Weber, Thomas Engleitner, Roman Maresch, Jolanta Slawska, Richard Lewis, Rouzanna Istvanffy, Stefan Habringer, Katja Steiger, Armin Baiker, Robert A. J. Oostendorp, Cornelius Miething, Hans-Peter Lenhof, Florian Bassermann, Björn Chapuy, Matthias Wirth, Elmar Wolf, Roland Rad, Stefan Müller, Ulrich Keller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
SUMOylation is a post-translational modification that has been shown to be altered in cancer. Here, the authors show that loss of the SUMO isopeptidase SENP6 leads to unrestricted SUMOylation and genomic instability promoting lymphomagenesis and gene
Externí odkaz:
https://doaj.org/article/ba5bc46837534430996429dd0c309256
Akademický článek
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Autor:
Oliver Hartmann, Michaela Reissland, Carina R. Maier, Thomas Fischer, Cristian Prieto-Garcia, Apoorva Baluapuri, Jessica Schwarz, Werner Schmitz, Martin Garrido-Rodriguez, Nikolett Pahor, Clare C. Davies, Florian Bassermann, Amir Orian, Elmar Wolf, Almut Schulze, Marco A. Calzado, Mathias T. Rosenfeldt, Markus E. Diefenbacher
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Lung cancer is the most common cancer worldwide and the leading cause of cancer-related deaths in both men and women. Despite the development of novel therapeutic interventions, the 5-year survival rate for non-small cell lung cancer (NSCLC) patients
Externí odkaz:
https://doaj.org/article/25bb6c9a9e3b4539a37791d85b52657e
Autor:
Gerlach, Jennifer M., Furrer, Michael, Gallant, Maria, Birkel, Dirk, Baluapuri, Apoorva, Wolf, Elmar, Gallant, Peter
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct . 114(44), E9224-E9232.
Externí odkaz:
https://www.jstor.org/stable/26488876
Autor:
Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, Olga Sumara, Julia Hofstetter, Steffi Herold, Jacqueline Kalb, Apoorva Baluapuri, Evon Poon, Colin Kwok, Louis Chesler, Hans Michael Maric, David S. Rickman, Elmar Wolf, Richard Bayliss, Susanne Walz, Martin Eilers
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3483-3497 (2017)
Summary: MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma
Externí odkaz:
https://doaj.org/article/09207f0506bb47e089f8a4b47d59ee99
Autor:
Daniel Solvie, Apoorva Baluapuri, Leonie Uhl, Daniel Fleischhauer, Theresa Endres, Dimitrios Papadopoulos, Amel Aziba, Abdallah Gaballa, Ivan Mikicic, Ekaterina Isaakova, Celeste Giansanti, Jennifer Jansen, Marvin Jungblut, Teresa Klein, Christina Schülein-Völk, Hans Maric, Sören Doose, Markus Sauer, Petra Beli, Andreas Rosenwald, Matthias Dobbelstein, Elmar Wolf, Martin Eilers
Publikováno v:
Nature. 612:148-155
Oncoproteins of the MYC family drive the development of numerous human tumours
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7ed7ca17b0ff6d2e1e4c473ef0801a
https://doi.org/10.1038/s41586-022-05469-4
https://doi.org/10.1038/s41586-022-05469-4
Autor:
Christoph Otto, Carolin Kastner, Stefanie Schmidt, Konstantin Uttinger, Apoorva Baluapuri, Sarah Denk, Mathias T. Rosenfeldt, Andreas Rosenwald, Florian Roehrig, Carsten P. Ade, Christina Schuelein‐Voelk, Markus E. Diefenbacher, Christoph‐Thomas Germer, Elmar Wolf, Martin Eilers, Armin Wiegering
Publikováno v:
Molecular Oncology. 16:2788-2809
Ribosomal biogenesis and protein synthesis are deregulated in most cancers, suggesting that interfering with translation machinery may hold significant therapeutic potential. Here, we show that loss of the tumor suppressor adenomatous polyposis coli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dbeee680a8e5e23f2242fcdfafeab88
https://doi.org/10.1002/1878-0261.13265
https://doi.org/10.1002/1878-0261.13265
Autor:
Grit Pattschull, Susanne Walz, Marco Gründl, Melissa Schwab, Eva Rühl, Apoorva Baluapuri, Anita Cindric-Vranesic, Susanne Kneitz, Elmar Wolf, Carsten P. Ade, Andreas Rosenwald, Björn von Eyss, Stefan Gaubatz
Publikováno v:
Cell Reports, Vol 27, Iss 12, Pp 3533-3546.e7 (2019)
Summary: YAP and TAZ, downstream effectors of the Hippo pathway, are important regulators of proliferation. Here, we show that the ability of YAP to activate mitotic gene expression is dependent on the Myb-MuvB (MMB) complex, a master regulator of ge
Externí odkaz:
https://doaj.org/article/c8b9040b38cd47f79ad6523a968695d8