Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye

Autor: Michael, IP, Westenskow, PD, Hacibekiroglu, S, Greenwald, AC, Ballios, BG, Kurihara, T, Li, Z, Warren, CM, Zhang, P, Aguilar, E, Donaldson, L, Marchetti, V, Baba, T, Hussein, SM, Sung, HK, Iruela-Arispe, ML, Rini, JM, Van der Kooy, D, Friedlander, M, Nagy, A

Publikováno v: EMBO molecular medicine, vol 6, iss 5
Michael, IP; Westenskow, PD; Hacibekiroglu, S; Greenwald, AC; Ballios, BG; Kurihara, T; et al.(2014). Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye. EMBO Molecular Medicine, 6(5), 604-623. doi: 10.1002/emmm.201303708. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/91w0c420

Current therapeutic antiangiogenic biologics used for the treatment of pathological ocular angiogenesis could have serious side effects due to their interference with normal blood vessel physiology. Here, we report the generation of novel antivascula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::23b857021c443628686d9d8d8bb7ebbf
https://escholarship.org/uc/item/91w0c420

Vitamin A deficiency retinopathy in the setting of celiac disease and liver fibrosis.

Autor: Pereira A; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada., Wright T; Kensington Vision and Research Center, University of Toronto, Toronto, ON, Canada., Weisbrod D; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada., Ballios BG; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada. brian.ballios@mail.utoronto.ca.; Kensington Vision and Research Center, University of Toronto, Toronto, ON, Canada. brian.ballios@mail.utoronto.ca.; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada. brian.ballios@mail.utoronto.ca.; Department of Ophthalmology, Krembil Research Institute, University Health Network, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada. brian.ballios@mail.utoronto.ca.

Publikováno v: Documenta ophthalmologica. Advances in ophthalmology [Doc Ophthalmol] 2024 Oct; Vol. 149 (2), pp. 125-131. Date of Electronic Publication: 2024 Jun 03.

X-linked cone dystrophy with an uncommon tapetal-like sheen caused by a novel RPGR variant.

Autor: Zhai Y; Hospital for Sick Children, University of Toronto, Toronto, ON., Wright T; University of Toronto, Toronto, ON; Kensington Vision and Research Centre, Toronto, ON., Ballios BG; University of Toronto, Toronto, ON; Kensington Vision and Research Centre, Toronto, ON; University Health Network, Toronto, ON; Krembil Research Institute, University Health Network, Toronto, ON. Electronic address: brian.ballios@mail.utoronto.ca.

Publikováno v: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie [Can J Ophthalmol] 2024 Jun; Vol. 59 (3), pp. e289-e293. Date of Electronic Publication: 2023 Dec 18.

Ensemble of deep convolutional neural networks is more accurate and reliable than board-certified ophthalmologists at detecting multiple diseases in retinal fundus photographs.

Autor: Pandey PU; School of Biomedical Engineering, The University of British Columbia, Vancouver, British Columbia, Canada., Ballios BG; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Kensington Vision and Research Centre and Kensington Research Institute, Toronto, Ontario, Canada., Christakis PG; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Kensington Vision and Research Centre and Kensington Research Institute, Toronto, Ontario, Canada., Kaplan AJ; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada., Mathew DJ; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Kensington Vision and Research Centre and Kensington Research Institute, Toronto, Ontario, Canada., Ong Tone S; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Sunnybrook Research Institute, Toronto, Ontario, Canada., Wan MJ; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada., Micieli JA; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.; Kensington Vision and Research Centre and Kensington Research Institute, Toronto, Ontario, Canada.; Department of Ophthalmology, St. Michael's Hospital, Unity Health, Toronto, Ontario, Canada., Wong JCY; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada jovi.wong@mail.utoronto.ca.

Publikováno v: The British journal of ophthalmology [Br J Ophthalmol] 2024 Feb 21; Vol. 108 (3), pp. 417-423. Date of Electronic Publication: 2024 Feb 21.

Deep phenotypic characterization of the retinal dystrophy in patients with RNU4ATAC-associated Roifman syndrome.

Autor: Ballios BG; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada., Mandola A; Division of Immunology and Allergy, The Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada., Tayyib A; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Tumber A; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Garkaby J; Division of Immunology and Allergy, The Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada., Vong L; The Canadian Centre for Primary Immunodeficiency and The Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, The Hospital for Sick Children, Toronto, ON, Canada., Heon E; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada., Roifman CM; Division of Immunology and Allergy, The Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada.; The Canadian Centre for Primary Immunodeficiency and The Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, The Hospital for Sick Children, Toronto, ON, Canada., Vincent A; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada. ajoy.vincent@sickkids.ca.; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, ON, Canada. ajoy.vincent@sickkids.ca.

Publikováno v: Eye (London, England) [Eye (Lond)] 2023 Dec; Vol. 37 (18), pp. 3734-3742. Date of Electronic Publication: 2023 May 24.