Natural Killer Cells in Perinatally HIV-1-Infected Children Exhibit Less Degranulation Compared to HIV-1-Exposed Uninfected Children and Their Expression of KIR2DL3, NKG2C, and NKp46 Correlates with Disease Severity1

Autor: Ballan, Wassim M., Vu, Bien-Aimee N., Long, Brian R., Loo, Christopher P., Michaëlsson, Jakob, Barbour, Jason D., Lanier, Lewis L., Wiznia, Andrew A., Abadi, Jacobo, Fennelly, Glenn J., Rosenberg, Michael G., Nixon, Douglas F.

NK cells play an integral role in the innate immune response by targeting virally infected and transformed cells with direct killing and providing help to adaptive responses through cytokine secretion. Whereas recent studies have focused on NK cells

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https://europepmc.org/articles/PMC4271645/

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Natural killer cells in perinatally HIV-1-infected children exhibit less degranulation compared to HIV-1-exposed uninfected children and their expression of KIR2DL3, NKG2C, and NKp46 correlates with disease severity.

Autor: Ballan WM; Division of Experimental Medicine, Department of Medicine, University of California-San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA. wassimballan@gmail.com, Vu BA, Long BR, Loo CP, Michaëlsson J, Barbour JD, Lanier LL, Wiznia AA, Abadi J, Fennelly GJ, Rosenberg MG, Nixon DF

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2007 Sep 01; Vol. 179 (5), pp. 3362-70.