Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Balint, Otvos"'
Autor:
Tyler J. Alban, Matthew M. Grabowski, Balint Otvos, Defne Bayik, Wesley Wang, Ajay Zalavadia, Vlad Makarov, Katie Troike, Mary McGraw, Anja Rabljenovic, Adam Lauko, Chase Neumann, Gustavo Roversi, Kristin A. Waite, Gino Cioffi, Nirav Patil, Thuy T. Tran, Kathleen McCortney, Alicia Steffens, C. Marcela Diaz, J. Mark Brown, Kathleen M. Egan, Craig M. Horbinski, Jill S. Barnholtz-Sloan, Prajwal Rajappa, Michael A. Vogelbaum, Richard Bucala, Timothy A. Chan, Manmeet S. Ahluwalia, Justin D. Lathia
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Intratumoral heterogeneity is a defining hallmark of glioblastoma, driving drug resistance and ultimately recurrence. Many somatic drivers of microenvironmental change have been shown to affect this heterogeneity and, ultimately, the treatment respon
Externí odkaz:
https://doaj.org/article/235cfdd3465841ec8a0ca9c96d6c14cb
Autor:
Tyler J. Alban, Defne Bayik, Balint Otvos, Anja Rabljenovic, Lin Leng, Leu Jia-Shiun, Gustavo Roversi, Adam Lauko, Arbaz A. Momin, Alireza M. Mohammadi, David M. Peereboom, Manmeet S. Ahluwalia, Kazuko Matsuda, Kyuson Yun, Richard Bucala, Michael A. Vogelbaum, Justin D. Lathia
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The application of tumor immunotherapy to glioblastoma (GBM) is limited by an unprecedented degree of immune suppression due to factors that include high numbers of immune suppressive myeloid cells, the blood brain barrier, and T cell sequestration t
Externí odkaz:
https://doaj.org/article/b0517335ef4c4e3faf3230da1829efe0
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fc2be5baaa02c29a761e36a940bdd0
https://doi.org/10.1158/2159-8290.22535263
https://doi.org/10.1158/2159-8290.22535263
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Gene list for network medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f8cc337b4422599431580de88f85dd
https://doi.org/10.1158/2159-8290.22535260.v1
https://doi.org/10.1158/2159-8290.22535260.v1
Data from Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner
Autor:
Justin D. Lathia, Feixiong Cheng, Manmeet S. Ahluwalia, Tae Hyun Hwang, Ahmad M. Khalil, Bjarne Winther Kristensen, Craig Horbinski, Michael A. Vogelbaum, Balint Otvos, Matthew M. Grabowski, Mia Sorensen, Mary McGraw, Tyler J. Alban, Alice Lo, Dionysios C. Watson, Gustavo Roversi, Adam Lauko, Daniel J. Silver, Daniel Vail, Changjin Hong, Chihyun Park, Yadi Zhou, Defne Bayik
Myeloid-derived suppressor cells (MDSC) that block antitumor immunity are elevated in glioblastoma (GBM) patient blood and tumors. However, the distinct contributions of monocytic (mMDSC) versus granulocytic (gMDSC) subsets have yet to be determined.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e0a630646e5b7b2422e3f94b7612de
https://doi.org/10.1158/2159-8290.c.6547804.v1
https://doi.org/10.1158/2159-8290.c.6547804.v1
Autor:
Justin D. Lathia, Peter E. Fecci, Michael A. Vogelbaum, Manmeet S. Ahluwalia, Gene H. Barnett, Alireza M. Mohammadi, Charlie Androjna, Sarah Johnson, Anja Rabljenovic, Tomas Radivoyevitch, Erin E. Mulkearns-Hubert, Defne Bayik, Matthew M. Grabowski, Tyler J. Alban, Balint Otvos
Purpose:Glioblastoma (GBM) immunotherapy clinical trials are generally initiated after standard-of-care treatment—including surgical resection, perioperative high-dose steroid therapy, chemotherapy, and radiation treatment—has either begun or fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c754b628c0a8f6914a50a0502301a1
https://doi.org/10.1158/1078-0432.c.6530484.v1
https://doi.org/10.1158/1078-0432.c.6530484.v1
Autor:
Justin D. Lathia, Peter E. Fecci, Michael A. Vogelbaum, Manmeet S. Ahluwalia, Gene H. Barnett, Alireza M. Mohammadi, Charlie Androjna, Sarah Johnson, Anja Rabljenovic, Tomas Radivoyevitch, Erin E. Mulkearns-Hubert, Defne Bayik, Matthew M. Grabowski, Tyler J. Alban, Balint Otvos
Supplementary Figures 1-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79db2696cb399dbd733477034c5e2e5b
https://doi.org/10.1158/1078-0432.22480611
https://doi.org/10.1158/1078-0432.22480611
Autor:
Masahiro Hitomi, Loic P. Deleyrolle, Erin E. Mulkearns-Hubert, Awad Jarrar, Meizhang Li, Maksim Sinyuk, Balint Otvos, Sylvain Brunet, William A. Flavahan, Christopher G. Hubert, Winston Goan, James S. Hale, Alvaro G. Alvarado, Ao Zhang, Mark Rohaus, Muna Oli, Vinata Vedam-Mai, Jeff M. Fortin, Hunter S. Futch, Benjamin Griffith, Qiulian Wu, Chun-hong Xia, Xiaohua Gong, Manmeet S. Ahluwalia, Jeremy N. Rich, Brent A. Reynolds, Justin D. Lathia
Publikováno v:
Cell Reports, Vol 11, Iss 7, Pp 1031-1042 (2015)
The coordination of complex tumor processes requires cells to rapidly modify their phenotype and is achieved by direct cell-cell communication through gap junction channels composed of connexins. Previous reports have suggested that gap junctions are
Externí odkaz:
https://doaj.org/article/494a4a229a984f468e7f3e93cceb546e
Autor:
Matthew M Grabowski, Ethan S Srinivasan, Eugene J Vaios, Eric W Sankey, Balint Otvos, Daria Krivosheya, Alex Scott, Michael Olufawo, Jun Ma, Elena I Fomchenko, James E Herndon, Albert H Kim, Veronica L Chiang, Clark C Chen, Eric C Leuthardt, Gene H Barnett, John P Kirkpatrick, Alireza M Mohammadi, Peter E Fecci
Publikováno v:
Neuro-oncology advances. 4(1)
Background Improved survival for patients with brain metastases has been accompanied by a rise in tumor recurrence after stereotactic radiotherapy (SRT). Laser interstitial thermal therapy (LITT) has emerged as an effective treatment for SRT failures
Autor:
Manmeet S. Ahluwalia, Sarah Johnson, Tyler J. Alban, Charlie Androjna, Balint Otvos, Justin D. Lathia, Defne Bayik, Alireza M. Mohammadi, Erin E. Mulkearns-Hubert, Tomas Radivoyevitch, Matthew M. Grabowski, Michael A. Vogelbaum, Anja Rabljenovic, Peter E. Fecci, Gene H. Barnett
Publikováno v:
Clin Cancer Res
Purpose: Glioblastoma (GBM) immunotherapy clinical trials are generally initiated after standard-of-care treatment—including surgical resection, perioperative high-dose steroid therapy, chemotherapy, and radiation treatment—has either begun or fa