Polimorfismo +49 A/G del gen del antígeno 4 del linfocito T citotóxico (CTLA-4) en la diabetes tipo 1: Asociación con el perfil de anticuerpos y citoquinas

Autor: Pérez B, Francisco, Codner D, Ethel, Ángel B, Bárbara, Balic N, Iván, Carrasco P, Elena

Publikováno v: Revista médica de Chile, Volume: 137, Issue: 3, Pages: 321-328, Published: MAR 2009

Background: Cytotoxic T lymphocyte associated antigen 4 (CTLA-4) has been one ofthe non HLA genes more commonly studied in type 1 diabetes mellitus (TID). CTLA-4 is a co-stimulation protein that has a key role in the negative regulation ofT cells and

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872009000300001&lng=en&tlng=en

[+49 A/G genetic polymorphism of cytotoxic T lymphocyte associated antigen 4 (CTLA-4) in type 7 diabetes: association with autoantibodies and cytokines].

Autor: Pérez B F; Laboratorio de Epidemiología Nutricional, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile, Santiago, Chile. fperez@inta.cl, Codner D E, Angel B B, Balic N I, Carrasco P E

Publikováno v: Revista medica de Chile [Rev Med Chil] 2009 Mar; Vol. 137 (3), pp. 321-8. Date of Electronic Publication: 2009 Jun 15.