Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Balgi AD"'
Autor:
Baradaran-Heravi, A, Bauer, CC, Pickles, IB, Hosseini-Farahabadi, S, Balgi, AD, Choi, K, Linley, DM, Beech, DJ, Roberge, M, Bon, RS
Publikováno v:
Journal of Biological Chemistry. 298:101546
Nonsense mutations, which occur in ∼11% of patients with genetic disorders, introduce premature termination codons (PTCs) that lead to truncated proteins and promote nonsense-mediated mRNA decay. Aminoglycosides such as G418 permit PTC readthrough,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0544fa96a3992234d8b9eb9f33eb293f
https://doi.org/10.1016/j.jbc.2021.101546
https://doi.org/10.1016/j.jbc.2021.101546
Autor:
Persaud R; Departments of Chemistry and Earth Ocean & Atmospheric Sciences, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada., Li SC; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada; RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, Japan., Chao JD; Division of Infectious Disease, Departments of Medicine and Microbiology and immunology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Forestieri R; Departments of Chemistry and Earth Ocean & Atmospheric Sciences, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada., Donohue E; Deptartment of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Balgi AD; Deptartment of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Zheng X; Division of Infectious Disease, Departments of Medicine and Microbiology and immunology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Chao JT; Department of Cellular and Physiological Sciences, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Yashiroda Y; RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, Japan., Yoshimura M; RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, Japan., Loewen CJR; Department of Cellular and Physiological Sciences, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada., Gingras AC; Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada., Boone C; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada; Department of Molecular Genetics, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada; RIKEN Center for Sustainable Resource Science, 2-1 Hirosawa, Wako, Saitama, Japan. Electronic address: charlie.boone@utoronto.ca., Av-Gay Y; Division of Infectious Disease, Departments of Medicine and Microbiology and immunology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address: yossi@mail.ubc.ca., Roberge M; Deptartment of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address: michelr@mail.ubc.ca., Andersen RJ; Departments of Chemistry and Earth Ocean & Atmospheric Sciences, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada. Electronic address: raymond.andersen@ubc.ca.
Publikováno v:
Cell chemical biology [Cell Chem Biol] 2022 May 19; Vol. 29 (5), pp. 870-882.e11. Date of Electronic Publication: 2021 Sep 13.
Autor:
Gerak CAN; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Zhang SM; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Sadowski IJ; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Sessions RB; School of Biochemistry, University of Bristol, Bristol, UK., McIntosh LP; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.; Department of Chemistry, University of British Columbia, Vancouver, BC, Canada., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.
Publikováno v:
SLAS discovery : advancing life sciences R & D [SLAS Discov] 2021 Jun; Vol. 26 (5), pp. 698-711. Date of Electronic Publication: 2020 Dec 21.
Autor:
Baradaran-Heravi A; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Hosseini-Farahabadi S; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Choi K; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Has C; Department of Dermatology, Medical Center-University of Freiburg, Faculty of Medicine, Freiburg, Germany., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2021 Apr 19; Vol. 49 (7), pp. 3692-3708.
Autor:
Attwood KM; Department of Surgery, Dalhousie University, Halifax, NS, Canada., Robichaud A; Department of Medical Neuroscience, Dalhousie University, Halifax, NS, Canada.; Division of Neurosurgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada., Westhaver LP; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Castle EL; Department of Microbiology & Immunology, Dalhousie University, Halifax, NS, Canada., Brandman DM; Division of Neurosurgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada., Balgi AD; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Roberge M; Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Colp P; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Croul S; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Kim I; Department of Medicine, Dalhousie University, Halifax, NS, Canada., McCormick C; Department of Microbiology & Immunology, Dalhousie University, Halifax, NS, Canada., Corcoran JA; Department of Microbiology, Immunology and Infectious Disease, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada., Weeks A; Department of Surgery, Dalhousie University, Halifax, NS, Canada. a.weeks@dal.ca.; Department of Medical Neuroscience, Dalhousie University, Halifax, NS, Canada. a.weeks@dal.ca.; Division of Neurosurgery, Department of Surgery, Dalhousie University, Halifax, NS, Canada. a.weeks@dal.ca.
Publikováno v:
Cell death & disease [Cell Death Dis] 2020 Nov 17; Vol. 11 (11), pp. 989. Date of Electronic Publication: 2020 Nov 17.
Autor:
Duncan MC; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada., Onguéné PA; Department of Chemistry, University Institute of Wood Technology Mbalmayo, University of Yaoundé I, Mbalmayo, Cameroon., Kihara I; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada., Nebangwa DN; Department of Biochemistry and Molecular Biology, University of Buea, CM-00237 Buea, Cameroon., Naidu ME; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada., Williams DE; Departments of Chemistry and Earth, Ocean & Atmospheric Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Andrae-Marobela K; Department of Biological Sciences, University of Botswana, Gaborone, Botswana., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada., Andersen RJ; Departments of Chemistry and Earth, Ocean & Atmospheric Sciences, University of British Columbia, Vancouver, BC V6T 1Z4, Canada., Niikura M; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada., Ntie-Kang F; Department of Chemistry, University of Buea, CM-00237 Buea, Cameroon.; Institute of Pharmacy, Martin-Luther University Halle-Wittenberg, 06120 Halle, Germany.; Institute of Botany, Technical University of Dresden, 01217 Dresden, Germany., Tietjen I; Faculty of Health Sciences, Simon Fraser University, Burnaby, BC V5A 1S6, Canada.; The Wistar Institute, Philadelphia, PA 19104, USA.
Publikováno v:
Molecules (Basel, Switzerland) [Molecules] 2020 Jun 24; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 24.
Autor:
Frew J; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada., Baradaran-Heravi A; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada., Wu X; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada., Yan TD; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada., Arns S; adMare BioInnovations, Vancouver, British Columbia, Canada., Shidmoossavee FS; adMare BioInnovations, Vancouver, British Columbia, Canada., Tan J; adMare BioInnovations, Vancouver, British Columbia, Canada., Jaquith JB; JAQJAM Consulting, Cobourg, Ontario, Canada., Jansen-West KR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lynn FC; Department of Surgery, University of British Columbia, Faculty of Medicine, Vancouver, British Columbia, Canada., Gao FB; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Petrucelli L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Feldman HH; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada.; Department of Neurosciences, University of California, San Diego, San Diego, CA, USA., Mackenzie IR; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada., Nygaard HB; Division of Neurology, University of British Columbia, Vancouver, British Columbia, Canada. haakon.nygaard@ubc.ca.
Publikováno v:
Molecular neurodegeneration [Mol Neurodegener] 2020 Mar 16; Vol. 15 (1), pp. 21. Date of Electronic Publication: 2020 Mar 16.
Autor:
Rabea SM; Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, British Columbia V6T 1Z3, Canada., Baradaran-Heravi A; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada., Krause A; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada., Hosseini Farahabadi S; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada., Grierson DS; Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall, Vancouver, British Columbia V6T 1Z3, Canada.
Publikováno v:
ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Apr 09; Vol. 10 (5), pp. 726-731. Date of Electronic Publication: 2019 Apr 09 (Print Publication: 2019).
Autor:
Baradaran-Heravi A; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Niesser J; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Choi K; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Zimmerman C; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., South AP; Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, PA 19107., Anderson HJ; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Strynadka NC; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3., Bally MB; Department of Experimental Therapeutics, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 1L3., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3; michelr@mail.ubc.ca.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2017 Mar 28; Vol. 114 (13), pp. 3479-3484. Date of Electronic Publication: 2017 Mar 13.
Autor:
Arns S; The Centre for Drug Research and Development, Vancouver, BC, Canada., Balgi AD; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada., Shimizu Y; The Centre for Drug Research and Development, Vancouver, BC, Canada., Pfeifer TA; The Centre for Drug Research and Development, Vancouver, BC, Canada., Kumar N; The Centre for Drug Research and Development, Vancouver, BC, Canada., Shidmoossavee FS; The Centre for Drug Research and Development, Vancouver, BC, Canada., Sun S; The Centre for Drug Research and Development, Vancouver, BC, Canada., Tai SS; Faculty of Heath Sciences, Simon Fraser University, Burnaby, BC, Canada., Agafitei O; Faculty of Heath Sciences, Simon Fraser University, Burnaby, BC, Canada., Jaquith JB; The Centre for Drug Research and Development, Vancouver, BC, Canada., Bourque E; The Centre for Drug Research and Development, Vancouver, BC, Canada., Niikura M; Faculty of Heath Sciences, Simon Fraser University, Burnaby, BC, Canada., Roberge M; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada. Electronic address: michelr@mail.ubc.ca.
Publikováno v:
European journal of medicinal chemistry [Eur J Med Chem] 2016 Sep 14; Vol. 120, pp. 64-73. Date of Electronic Publication: 2016 May 07.