Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Baldev, Gautam"'
1
Triple reuptake inhibitor potentially ameliorates the chronic unpredictable stress induced comorbid depression and anxiety: A Behavioural based rodent test battery evaluation
Autor: Baldev Gautam, Shvetank Bhatt, Ankur Jindal, Dilip Kumar Pandey
Publikováno v: Indian Journal of Pharmaceutical Education and Research. 49:46-57
Depression and anxiety tend to be the most prevalent conditions among the multitude of neurobehavioural disorders which cause distress in chronic stress condition. The objective of the present investigation was to examine the effect of DOV-216303 (a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c3f4e4a8f8f7ae9afdfcff86c47b06f
https://doi.org/10.5530/ijper.49.1.7
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2
Antidepressant-like activity of 2-(4-phenylpiperazin-1-yl)-1, 8-naphthyridine-3-carboxylic acid (7a), a 5-HT3 receptor antagonist in behaviour based rodent models: Evidence for the involvement of serotonergic system
Autor: Baldev Gautam, Radhakrishnan Mahesh, Arghya Kusum Dhar, Ankur Jindal
Publikováno v: Pharmacology Biochemistry and Behavior. 109:91-97
The present study was designed to investigate the putative antidepressant-like activity of 7a, a 5-HT3 receptor antagonist, (although indirect evidence of 5-HT3 antagonism) with an optimal log P (3.35) and pA2 value (7.6) greater than ondansetron (pA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7267a7d46876691a5e89a6ec0760c534
https://doi.org/10.1016/j.pbb.2013.05.006
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3
Effect of combination of ketanserin and escitalopram on behavioral anomalies after olfactory bulbectomy: prediction of quick onset of antidepressant action
Autor: Dilip Kumar Pandey, Baldev Gautam, Ankur Jindal, Shvetank Bhatt
Publikováno v: Indian Journal of Pharmacology
Objectives: Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressant drugs. The addition of low dose of 5-hydroxytryptamine type 2A enhances the therapeutic effect of SSRIs. The purpose of the present studies wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785e5a8e8f171866a6d5b9be2d691f02
https://pubmed.ncbi.nlm.nih.gov/25538337
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4
Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n)
Autor: Thangaraj Devadoss, Radhakrishnan Mahesh, Dilip Kumar Pandey, Ankur Jindal, Shvetank Bhatt, Baldev Gautam
Publikováno v: Journal of Young Pharmacists : JYP
The present study was designed to evaluate the antidepressant potential of 5-HT3 receptor antagonist N-n-propyl-3-ethoxyquinoxaline-2-carboxamide (6n). The compound '6n' with optimum log P and pA 2 value identified from a series of compounds synthesi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758bd28e7e885a17e13044a82c55f07b
https://pubmed.ncbi.nlm.nih.gov/23493308
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5
Antidepressant-like effect of etazolate, a cyclic nucleotide phosphodiesterase 4 inhibitor--an approach using rodent behavioral antidepressant tests battery
Autor: Dilip Kumar Pandey, Shvetank Bhatt, Baldev Gautam, Radhakrishnan Mahesh, Ankur Jindal
Publikováno v: European journal of pharmacology. 689(1-3)
Etazolate, a pyrazolopyridine class derivative is selective inhibitor of type 4 phosphodiesterase (PDE4), an enzyme catalyzes the hydrolysis of cyclic nucleotide viz. cAMP & regulates cAMP signal transduction. Enhancing cAMP signal transduction by in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d321a87fe705198ed4a57d7b029bbda0
https://pubmed.ncbi.nlm.nih.gov/22698578
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6
Anti-depressant-like activity of a novel serotonin type-3 (5-HT3) receptor antagonist in rodent models of depression
Autor: Deepali, Gupta, Thangaraj, Devadoss, Shvetank, Bhatt, Baldev, Gautam, Ankur, Jindal, Dilip, Pandey, Radhakrishnan, Mahesh
Publikováno v: Indian journal of experimental biology. 49(8)
N-Cyclohexyl-3-methoxyquinoxalin-2-carboxamide (QCM-13), a novel 5-HT3 antagonist identified from a series of compounds with higher pA2 (7.6) and good log P (2.91) value was screened in rodent models of depression such as forced swim test (FST), tail
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8313aaff80eee32e4b67c5603caeb814
https://pubmed.ncbi.nlm.nih.gov/21870430
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7
Evaluation of anti-depressant-like activity of linezolid, an oxazolidinone class derivative - an investigation using behavioral tests battery of depression
Autor: Dilip Kumar Pandey, Baldev Gautam, Radhakrishnan Mahesh, Ankur Jindal, Shvetank Bhatt
Publikováno v: Biochemical and biophysical research communications. 409(4)
Linezolid, an oxazolidinone class derivative is a reversible and nonselective inhibitor of monoamine oxidase (MAO), predominantly for MAO-A type. MAO-A is a key enzyme regulating the catabolism of catecholamine neurotransmitters in the brain. It is w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e5cb585e359c18eac032126c52f233
https://pubmed.ncbi.nlm.nih.gov/21624345
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